Synergistic effects of interferon γ and tumour necrosis factor α on T84 cell function

A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-downregulated with the receptor of tumor necrosis factor.

1989 • 1,436 citations

The Tumor Necrosis Factor Ligand and Receptor Families

1996 • 1,239 citations

A distinct array of proinflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasion.

1995 • 1,205 citations

Treatment of Crohn's disease with anti-tumor necrosis factor chimeric monoclonal antibody (cA2)

1995 • 1,103 citations

An enzyme-release assay for natural cytotoxicity

1983 • 1,063 citations

Gene induction by gamma-irradiation leads to DNA fragmentation in lymphocytes.

1987 • 923 citations

An Improved Method for Prenatal Diagnosis of Genetic Diseases by Analysis of Amplified DNA Sequences

1987 • 811 citations

Two tumour necrosis factor receptors: structure and function

1995 • 800 citations

Interferon-gamma directly affects barrier function of cultured intestinal epithelial monolayers.

1989 • 761 citations

Tumour necrosis factor-alpha and interferon-gamma production measured at the single cell level in normal and inflamed human intestine

1990 • 489 citations

Altered Th1/Th2 cytokine profiles in the intestinal mucosa of patients with inflammatory bowel disease as assessed by quantitative reversed transcribed polymerase chain reaction (RT-PCR)

1995 • 400 citations

Randomised controlled trial of CDP571 antibody to tumour necrosis factor-α in Crohn's disease

1997 • 400 citations

A human colonic tumor cell line that maintains vectorial electrolyte transport

1984 • 398 citations

Expression and characterization of the cystic fibrosis transmembrane conductance regulator

1990 • 340 citations

Induction of the synthesis of tumor necrosis factor receptors by interferon-gamma.

1986 • 328 citations

Interleukin-2- and interferon-gamma-secreting T cells in normal and diseased human intestinal mucosa.

1993 • 324 citations

A second tumor necrosis factor receptor gene product can shed a naturally occurring tumor necrosis factor inhibitor.

1990 • 292 citations

Interferon-γ Modulates a p53-independent Apoptotic Pathway and Apoptosis-related Gene Expression

1997 • 276 citations

Divergent induction of apoptosis and IL-8 secretion in HT-29 cells in response to TNF-alpha and ligation of Fas antigen.

1995 • 248 citations

IFN-gamma modulation of epithelial barrier function. Time course, reversibility, and site of cytokine binding.

1993 • 246 citations

Autocrine regulation of epithelial permeability by hypoxia: Role for polarized release of tumor necrosis factor α

1998 • 193 citations

IL-4 directly modulates function of a model human intestinal epithelium.

1994 • 181 citations

Cloning of human tumor necrosis factor (TNF) receptor cDNA and expression of recombinant soluble TNF-binding protein.

1990 • 141 citations

Interferon-gamma induces a cell surface phenotype switch on T84 intestinal epithelial cells

1994 • 138 citations

Interferon-gamma downregulates CFTR gene expression in epithelial cells

1994 • 102 citations

Assessment of inflammatory events in epithelial permeability: a rapid screening method using fluorescein dextrans.

1995 • 87 citations

T cell-monocyte interactions regulate epithelial physiology in a coculture model of inflammation

1996 • 84 citations

Inhibition of cAMP- and Ca-dependent Cl- secretion by phorbol esters: inhibition of basolateral K+ channels

1993 • 66 citations

Effect of tumor necrosis factor‐α and interferon‐γ on the growth of a human salivary gland cell line

1994 • 52 citations

Expression of mRNA for 55-kDa and 75-kDa tumor necrosis factor (TNF) receptors in mouse cerebrovascular endothelium: effects of interleukin-1β, Interferon-γ and TNF-α on cultured cells

1995 • 50 citations

Renal allograft rejection: expression and function of VCAM-1 on tubular epithelial cells

1993 • 43 citations

Cytokine expression in intestinal mucosal biopsies. In situ hybridisation of the mRNA for interleukin-1 beta, interleukin-6 and tumour necrosis factor-alpha in inflammatory bowel disease.

1994 • 41 citations

An Improved Method for Prenatal Diagnosis of Genetic Diseases by Analysis of Amplified DNA Sequences

1988 • 19 citations

Expression of type a and b tumor necrosis factor (TNF) receptors on melanoma cells can be regulated by dbc‐AMP and IFN‐γ

1995 • 17 citations

Cloning, sequencing and partial functional characterization of the 5' region of the human p75 tumor necrosis factor receptor-encoding gene (TNF-R)

1994 • 12 citations