Dietary carotenoids inhibit neoplastic transformation and modulate gene expression in mouse and human cells

The Steroid and Thyroid Hormone Receptor Superfamily

1988 • 7,590 citations

The Effect of Vitamin E and Beta Carotene on the Incidence of Lung Cancer and Other Cancers in Male Smokers

1994 • 4,626 citations

Can dietary beta-carotene materially reduce human cancer rates?

1981 • 1,575 citations

Lipid peroxides and human diseases

1987 • 1,358 citations

Connexin43: a protein from rat heart homologous to a gap junction protein from liver.

1987 • 1,111 citations

Antioxidant functions of carotenoids

1989 • 916 citations

Quantitative and qualitative studies of chemical transformation of cloned C3H mouse embryo cells sensitive to postconfluence inhibition of cell division.

1973 • 843 citations

Regulation of terminal differentiation of cultured human keratinocytes by vitamin A

1981 • 756 citations

Genetic and immunochemical analysis of mutant p53 in human breast cancer cell lines.

1990 • 607 citations

Hepatocyte gap junctions are permeable to the second messenger, inositol 1,4,5-trisphosphate, and to calcium ions.

1989 • 596 citations

Connexin family of gap junction proteins

1990 • 553 citations

Carotenoids enhance gap junctional communication and inhibit lipid peroxidation in C3H/10T1/2 cells: relationship to their cancer chemopreventive action

1991 • 518 citations

Vegetables, fruits, and carotenoids and the risk of cancer

1991 • 472 citations

Growth inhibition of transformed cells correlates with their junctional communication with normal cells

1986 • 416 citations

Comparison of Low-Dose Isotretinoin with Beta Carotene to Prevent Oral Carcinogenesis

1993 • 402 citations

Rationale and strategies for chemoprevention of cancer in humans.

1987 • 366 citations

Transfection of C6 glioma cells with connexin 43 cDNA: analysis of expression, intercellular coupling, and cell proliferation.

1991 • 366 citations

Provitamin A Function of Carotenoids: The Conversion of β-Carotene into Vitamin A

1989 • 355 citations

DNA lesions, inducible DNA repair, and cell division: three key factors in mutagenesis and carcinogenesis.

1993 • 334 citations

Carotenoids up-regulate connexin43 gene expression independent of their provitamin A or antioxidant properties.

1992 • 330 citations

The development and application of a carotenoid database for fruits, vegetables, and selected multicomponent foods

1993 • 262 citations

Diverse carotenoids protect against chemically induced neoplastic transformation

1991 • 257 citations

Involvement of gap junctions in tumorigenesis: transfection of tumor cells with connexin 32 cDNA retards growth in vivo.

1991 • 246 citations

Retinoic acid improves epidermal morphogenesis

1989 • 239 citations

A Retinoic Acid Receptor-Specific Element Controls the Retinoic Acid Receptor-β Promoter

1990 • 235 citations

Anticarcinogenic effect of common carotenoids.

1993 • 231 citations

Gap junctional communication and development

1989 • 215 citations

The cell-to-cell channel of gap junctions

1987 • 206 citations

Response of oral leukoplakia to beta-carotene.

1990 • 172 citations

Enhancement of gap junctional communication by retinoids correlates with their ability to inhibit neoplastic transformation

1989 • 154 citations

β-Carotene and canthaxanthin inhibit chemically- and physically- induced neoplastic transformation in 10T1/2 cells

1988 • 146 citations

Coordinate control by vitamin A of keratin gene expression in human keratinocytes.

1985 • 133 citations

Growth retardation in glioma cells cocultured with cells overexpressing a gap junction protein.

1992 • 131 citations

Regulation of type I (epidermal) transglutaminase mRNA levels during squamous differentiation: down regulation by retinoids.

1989 • 119 citations

Comparative Aspects of Carotenoids and Retinoids as Chemopreventive Agents for Cancer

1989 • 104 citations

Retinoid‐enhanced gap junctional communication is achieved by increased levels of connexin 43 mRNA and protein

1990 • 101 citations

Retinoid-mediated transcriptional regulation of keratin genes in human epidermal and squamous cell carcinoma cells.

1991 • 100 citations

Nuclear receptors for retinoic acid and thyroid hormone regulate transcription of keratin genes.

1990 • 96 citations

The toxicity of beta-carotene☆☆☆

1985 • 89 citations

Retinoid suppression of transglutaminase activity and envelope competence in cultured human epidermal carcinoma cells

1985 • 77 citations

The Molecular Biology of Skin

1976 • 75 citations

Filaggrin production by cultured human epidermal keratinocytes and its regulation by retinoic acid

1990 • 58 citations

Evaluation of the Preruminant Calf as a Model for the Study of Human Carotenoid Metabolism ,

1992 • 55 citations

Efficacy of All-trans-β-Carotene, Canthaxanthin, and All-trans, 9-cis-, and 4-Oxoretinoic Acids in Inducing Differentiation of an F9 Embryonal Carcinoma RARβ-lacZ Reporter Cell Line

1995 • 55 citations

[6] Solubilization, cellular uptake, and activity of β-carotene and other carotenoids as inhibitors of neoplastic transformation in cultured cells

1993 • 52 citations

Expression of loricrin is negatively controlled by retinoic acid in human epidermis reconstructed in vitro

1992 • 52 citations

Remission of oral precancerous lesions of tobacco/areca nut chewers following administration of beta-carotene or vitamin A, and maintenance of the protective effect.

1991 • 46 citations

Retinoids suppress proliferation, induce cell spreading, and up-regulate connexin43 expression only in postconfluent 10T1/2 cells: implications for the role of gap junctional communication.

1994 • 42 citations

Relationship between dietary, serum, and tissue levels of carotenoids

1991 • 26 citations

Role of Gap Junctional Cell/Cell Communication in the Control of Proliferation and Neoplastic Transformation

1990 • 26 citations

Effects of micronutrients and antioxidants on lipid peroxidation in human plasma and in cell culture

1994 • 25 citations

Receptor-Mediated Action Without Receptor Occupancy: A Function for Cell-Cell Communication in Ovarian Follicles

1987 • 23 citations

Development of in vitro systems for chemoprevention research

1989 • 13 citations

The protein kinase C pathway in tumor promotion.

1989 • 12 citations