Changing Face of Microglia

Microglia: a sensor for pathological events in the CNS

1996 • 4,309 citations

The Classical Complement Cascade Mediates CNS Synapse Elimination

2007 • 2,812 citations

BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain

2005 • 1,836 citations

Resting Microglia Directly Monitor the Functional State of SynapsesIn Vivoand Determine the Fate of Ischemic Terminals

2009 • 1,469 citations

Hematopoietic Stem Cell Gene Therapy with a Lentiviral Vector in X-Linked Adrenoleukodystrophy

2009 • 1,439 citations

Bone Marrow-Derived Microglia Play a Critical Role in Restricting Senile Plaque Formation in Alzheimer's Disease

2006 • 1,191 citations

Macrophage polarization in tumour progression

2008 • 1,149 citations

Displacement of synaptic terminals from regenerating motoneurons by microglial cells

1968 • 845 citations

Wild-type microglia extend survival in PU.1 knockout mice with familial amyotrophic lateral sclerosis

2006 • 698 citations

Microglia: biology and pathology

2009 • 672 citations

Histopathologie des Nervensystems

1922 • 646 citations

Dystrophic (senescent) rather than activated microglial cells are associated with tau pathology and likely precede neurodegeneration in Alzheimer’s disease

2009 • 644 citations

HISTOPATHOLOGIE DES NERVENSYSTEMS

1923 • 542 citations

Immune Proteins in Brain Development and Synaptic Plasticity

2009 • 505 citations

Chronic stress alters the density and morphology of microglia in a subset of stress-responsive brain regions

2010 • 487 citations

Microglial control of neuronal death and synaptic properties

2006 • 433 citations

Hematopoietic Origin of Pathological Grooming in Hoxb8 Mutant Mice

2010 • 428 citations

Assessing Activation States in Microglia

2010 • 385 citations

Axotomy of the rat facial nerve leads to increased CR3 complement receptor expression by activated microglial cells

1988 • 368 citations

Developmental Neuronal Death in Hippocampus Requires the Microglial CD11b Integrin and DAP12 Immunoreceptor

2008 • 331 citations

Rett Syndrome Microglia Damage Dendrites and Synapses by the Elevated Release of Glutamate

2010 • 329 citations

Evidence for synaptic stripping by cortical microglia

2006 • 317 citations

Evidence for activation of microglia in patients with psychiatric illnesses

1999 • 315 citations

The Microglial Reaction in the Rat Dorsal Hippocampus following Transient Forebrain Ischemia

1991 • 301 citations

Massive gliosis induced by interleukin‐6 suppresses Aβ deposition in vivo: evidence against inflammation as a driving force for amyloid deposition

2009 • 297 citations

Bone-marrow-derived cells contribute to the recruitment of microglial cells in response to β-amyloid deposition in APP/PS1 double transgenic Alzheimer mice

2004 • 286 citations

Macrophage colony-stimulating factor induces the proliferation and survival of macrophages via a pathway involving DAP12 and β-catenin

2009 • 282 citations

Uniquely human evolution of sialic acid genetics and biology

2010 • 259 citations

Central nervous system perivascular cells are immunoregulatory cells that connect the CNS with the peripheral immune system

2001 • 238 citations

Region‐specific expression of immunoregulatory proteins on microglia in the healthy CNS

2008 • 236 citations

Microglia at brain stab wounds express connexin 43 andin vitroform functional gap junctions after treatment with interferon-γ and tumor necrosis factor-α

2001 • 218 citations

New expression of myelomonocytic antigens by microglia and perivascular cells following lethal motor neuron injury

1990 • 213 citations

Microglia activation in sepsis: a case-control study.

2007 • 201 citations

Life and Death of Microglia

2009 • 195 citations

Male Donor-derived Cells in the Brains of Female Sex-mismatched Bone Marrow Transplant Recipients

1993 • 184 citations

In vivo detection of microglial activation in frontotemporal dementia

2004 • 181 citations

Transformation of donor‐derived bone marrow precursors into host microglia during autoimmune CNS inflammation and during the retrograde response to axotomy

2001 • 155 citations

Bone-marrow-derived microglia: myth or reality?

2008 • 135 citations

A Human-Specific Gene in Microglia

2005 • 125 citations

Glutamate induces directed chemotaxis of microglia

2009 • 112 citations

Synaptic stripping in the human facial nucleus

1993 • 111 citations

Involvement of microglial P2X7 receptors and downstream signaling pathways in long-term potentiation of spinal nociceptive responses

2010 • 110 citations

Neural Cell Adhesion Molecule-Associated Polysialic Acid Regulates Synaptic Plasticity and Learning by Restraining the Signaling through GluN2B-Containing NMDA Receptors

2010 • 108 citations

Involvement of Spinal Microglial P2X7 Receptor in Generation of Tolerance to Morphine Analgesia in Rats

2010 • 101 citations

Developmental Regulation of TREM2 and DAP12 Expression in the Murine CNS: Implications for Nasu-Hakola Disease

2008 • 98 citations

Degenerating Synaptic Boutons in Prion Disease

2009 • 97 citations

Microglia and the Development of Spongiform Change in Creutzfeldt-Jakob Disease

1998 • 90 citations

Microglia activation in the hypothalamic PVN following myocardial infarction

2010 • 87 citations

Fusion of Microglia with Pyramidal Neurons after Retroviral Infection

2006 • 75 citations

Siglec receptors and hiding plaques in Alzheimer's disease

2009 • 72 citations

Activated Microglia in Nociception

2010 • 61 citations

Nasu‐Hakola disease: The first case reported by Nasu and review

2010 • 60 citations

Is Schizophrenia the Price of Human Central Nervous System Complexity?

2009 • 30 citations

Involvement of microglial activation in the brainstem in experimental dental injury and inflammation

2010 • 14 citations