Aberrant Macrophage and Neutrophil Population Dynamics and Impaired Th1 Response toListeria monocytogenesin Colony-Stimulating Factor 1-Deficient Mice

Development of T _H 1 CD4 ⁺ T Cells Through IL-12 Produced by Listeria -Induced Macrophages

1993 • 3,140 citations

Chemokines and leukocyte traffic

1998 • 2,755 citations

Cloning of a new cytokine that induces IFN-γ production by T cells

1995 • 2,584 citations

Xenogeneic Monoclonal Antibodies to Mouse Lymphoid Differentiation Antigens*

1979 • 1,989 citations

The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene

1990 • 1,763 citations

Multiple Defects of Immune Cell Function in Mice with Disrupted Interferon-γ Genes

1993 • 1,753 citations

Immune Response in Mice that Lack the Interferon-γ Receptor

1993 • 1,570 citations

Mac‐1: a macrophage differentiation antigen identified by monoclonal antibody

1979 • 1,144 citations

Immunity to Intracellular Bacteria

1993 • 1,085 citations

Total absence of colony-stimulating factor 1 in the macrophage-deficient osteopetrotic (op/op) mouse.

1990 • 1,012 citations

IL-12-Deficient Mice Are Defective in IFNγ Production and Type 1 Cytokine Responses

1996 • 991 citations

Interleukin‐8, a chemotactic and inflammatory cytokine

1992 • 941 citations

THE INFLUENCE OF IMMUNOLOGICALLY COMMITTED LYMPHOID CELLS ON MACROPHAGE ACTIVITY IN VIVO

1969 • 932 citations

Interleukin 12 and tumor necrosis factor alpha are costimulators of interferon gamma production by natural killer cells in severe combined immunodeficiency mice with listeriosis, and interleukin 10 is a physiologic antagonist.

1993 • 792 citations

Defects in Macrophage Recruitment and Host Defense in Mice Lacking the CCR2 Chemokine Receptor

1997 • 700 citations

An Eosinophil-Dependent Mechanism for the Antitumor Effect of Interleukin-4

1992 • 540 citations

Role of colony stimulating factor-1 in the establishment and regulation of tissue macrophages during postnatal development of the mouse

1994 • 538 citations

CSF‐1—A mononuclear phagocyte lineage‐specific hemopoietic growth factor

1983 • 536 citations

Constructing polycompetitor cDNAs for quantitative PCR

1993 • 323 citations

A rat anti-mouse T4 monoclonal antibody (H129.19) inhibits the proliferation of Ia-reactive T cell clones and delineates two phenotypically distinct (T4+, Lyt-2,3-, and T4-, Lyt-2,3+) subsets among anti-Ia cytolytic T cell clones.

1984 • 308 citations

Neutralization of IL-12 decreases resistance to Listeria in SCID and C.B-17 mice. Reversal by IFN-gamma.

1994 • 305 citations

Interleukin-6-deficient mice are highly susceptible to Listeria monocytogenes infection: correlation with inefficient neutrophilia

1995 • 300 citations

Role of Resident Peritoneal Macrophages and Mast Cells in Chemokine Production and Neutrophil Migration in Acute Inflammation: Evidence for an Inhibitory Loop Involving Endogenous IL-10

1999 • 300 citations

Studies in listeriosis show the strong symbiosis between the innate cellular system and the T‐cell response

1997 • 270 citations

Impaired Macrophage Function and Enhanced T Cell-Dependent Immune Response in Mice Lacking CCR5, the Mouse Homologue of the Major HIV-1 Coreceptor

1998 • 252 citations

Effector Cells of Both Nonhemopoietic and Hemopoietic Origin Are Required for Interferon (IFN)-γ– and Tumor Necrosis Factor (TNF)-α–dependent Host Resistance to the Intracellular Pathogen, Toxoplasma gondii

1999 • 244 citations

Identification of macrophages and dendritic cells in the osteopetrotic (op/op) mouse

1993 • 233 citations

Interleukin-6 Induces Monocyte Chemotactic Protein-1 in Peripheral Blood Mononuclear Cells and in the U937 Cell Line

1998 • 229 citations

Inter-relationship among macrophages, natural killer cells and neutrophils in early stages of Listeria resistance

1997 • 214 citations

Mononuclear phagocyte system of the mouse defined by immunohistochemical localization of antigen F4/80. Identification of resident macrophages in renal medullary and cortical interstitium and the juxtaglomerular complex

1983 • 189 citations

Direct observation and quantification of macrophage chemoattraction to the growth factor CSF-1

1996 • 177 citations

Abnormal differentiation of tissue macrophage populations in 'osteopetrosis' (op) mice defective in the production of macrophage colony-stimulating factor.

1991 • 166 citations

Mice Lacking Both Granulocyte Colony-Stimulating Factor (CSF) and Granulocyte-Macrophage CSF Have Impaired Reproductive Capacity, Perturbed Neonatal Granulopoiesis, Lung Disease, Amyloidosis, and Reduced Long-Term Survival

1997 • 161 citations

Three Phases of Phagocyte Contribution to Resistance against Listeria monocytogenes

1978 • 158 citations

Cytokine regulation of the macrophage (M phi) system studied using the colony stimulating factor-1-deficient op/op mouse

1996 • 148 citations

The M Cell as a Portal of Entry to the Lung for the Bacterial Pathogen Mycobacterium tuberculosis

1999 • 139 citations

Absence of Colony-Stimulating Factor-1 in Osteopetrotic (csfmoP/csfmOP) Mice Results in Male Fertility Defects1

1996 • 139 citations

Cutting Edge: Paradigm Revisited: Antibody Provides Resistance toListeriaInfection

1999 • 136 citations

Selective chemokine mRNA expression following brain injury

1998 • 115 citations

Regulation of macrophage Ia expression in mice with severe combined immunodeficiency: induction of Ia expression by a T cell-independent mechanism.

1986 • 110 citations

Pleiotropic Roles for CSF-1 in Development Defined by the Mouse Mutation Osteopetrotic

1996 • 109 citations

The role of Kupffer cells and regulation of neutrophil migration into the liver by macrophage inflammatory protein‐2 in primary listeriosis in mice

1999 • 98 citations

IL-12 is dispensable for innate and adaptive immunity against low doses of Listeria monocytogenes

1999 • 97 citations

Effector function of hepatocytes and Kupffer cells in the resolution of systemic bacterial infections

1992 • 97 citations

Production of Monocyte Chemotactic Protein‐1 By Rat Brain Macrophages

1996 • 95 citations

Role of IL-6 in activation of T cells for acquired cellular resistance to Listeria monocytogenes.

1994 • 67 citations

Selective Depletion of Liver and Splenic Macrophages Using Liposomes Encapsulating the Drug Dichloromethylene Diphosphonate: Effects on Antimicrobial Resistance

1991 • 64 citations

Roles of a Macrophage Receptor with Collagenous Structure(MARCO) in Host Defense and Heterogeneity of Splenic Marginal Zone Macrophages.

1999 • 64 citations

Disruption of the Cellular Inflammatory Response toListeria monocytogenesInfection in Mice with Disruptions in Targeted Genes

1998 • 61 citations

Differentiation of dendritic cell populations in macrophage colony-stimulating factor-deficient mice homozygous for the osteopetrosis (op) mutation

1993 • 61 citations

In vitro characterization of T cells from Mycobacterium w-vaccinated mice

1992 • 60 citations

IL-6 Produced by Kupffer Cells Induces STAT Protein Activation in Hepatocytes Early During the Course of Systemic Listerial Infections

1998 • 54 citations

Distinct in vivo functions of two macrophage subpopulations as evidenced by studies using macrophage‐deficient op/op mouse

1992 • 48 citations

Macrophage production during murine listeriosis: colony-stimulating factor 1 (CSF-1) and CSF-1-binding cells in genetically resistant and susceptible mice

1988 • 44 citations

Analysis of the Interrelationship between IL-12, TNF-α, and IFN-γ/Production during Murine Listeriosis

1995 • 42 citations

Elimination of resident macrophages from the livers and spleens of immune mice impairs acquired resistance against a secondary Listeria monocytogenes infection

1997 • 29 citations

Osteopetrotic (op/op) Mice Deficient in Macrophages Have the Ability to Mount a Normal T-Cell-Dependent Immune Response

1995 • 26 citations

NADPH diaphorase staining suggests a transient and localized contribution of nitric oxide to host defence against an intracellular pathogen in situ

1994 • 25 citations

Effects of macrophage colony-stimulating factor on reduction of viable bacteria and survival of mice during Listeria monocytogenes infection: characteristics of monocyte subpopulations

1991 • 22 citations

Colony-stimulating factor 1-dependent resident macrophages play a regulatory role in fighting Escherichia coli fecal peritonitis

1996 • 18 citations

Functional characterization of recombinant rat macrophage inflammatory protein-1 alpha and mRNA expression in pulmonary inflammation.

1998 • 18 citations

Delayed neutrophil apoptosis after total body irradiation in mice. The role of granulocyte-macrophage colony-stimulating factor in neutrophil function.

1998 • 4 citations