Combinatorial Expression of TRPV Channel Proteins Defines Their Sensory Functions and Subcellular Localization in C. elegans Neurons

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

1994 • 63,397 citations

THE GENETICS OF CAENORHABDITIS ELEGANS

1974 • 14,589 citations

The capsaicin receptor: a heat-activated ion channel in the pain pathway

1997 • 8,634 citations

Impaired Nociception and Pain Sensation in Mice Lacking the Capsaicin Receptor

2000 • 3,436 citations

Efficient gene transfer in C.elegans: extrachromosomal maintenance and integration of transforming sequences.

1991 • 3,108 citations

The Cloned Capsaicin Receptor Integrates Multiple Pain-Producing Stimuli

1998 • 3,026 citations

Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide

1999 • 2,128 citations

A capsaicin-receptor homologue with a high threshold for noxious heat

1999 • 1,547 citations

2.2 Mb of contiguous nucleotide sequence from chromosome III of C. elegans

1994 • 1,472 citations

Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol

1999 • 1,456 citations

Vanilloid Receptor–Related Osmotically Activated Channel (VR-OAC), a Candidate Vertebrate Osmoreceptor

2000 • 1,348 citations

Odorant-selective genes and neurons mediate olfaction in C. elegans

1993 • 1,177 citations

Capacitative calcium entry

1995 • 1,112 citations

The trp ion channel family

2001 • 1,108 citations

Subunit-Specific Rules Governing AMPA Receptor Trafficking to Synapses in Hippocampal Pyramidal Neurons

2001 • 1,073 citations

OTRPC4, a nonselective cation channel that confers sensitivity to extracellular osmolarity

2000 • 982 citations

Neurobiology of the Caenorhabditis elegans Genome

1998 • 912 citations

LTRPC7 is a Mg·ATP-regulated divalent cation channel required for cell viability

2001 • 900 citations

ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology

2001 • 877 citations

Uptake of Glutamate into Synaptic Vesicles by an Inorganic Phosphate Transporter

2000 • 792 citations

Meiotic Recombination in C. elegans Initiates by a Conserved Mechanism and Is Dispensable for Homologous Chromosome Synapsis

1998 • 775 citations

Divergent seven transmembrane receptors are candidate chemosensory receptors in C. elegans

1995 • 699 citations

A multivalent PDZ-domain protein assembles signalling complexes in a G-protein-coupled cascade

1997 • 625 citations

OSM-9, A Novel Protein with Structural Similarity to Channels, Is Required for Olfaction, Mechanosensation, and Olfactory Adaptation inCaenorhabditis elegans

1997 • 621 citations

Molecular Identification of the Apical Ca2+Channel in 1,25-Dihydroxyvitamin D3-responsive Epithelia

1999 • 587 citations

odr-10 Encodes a Seven Transmembrane Domain Olfactory Receptor Required for Responses to the Odorant Diacetyl

1996 • 550 citations

Selective Photostimulation of Genetically ChARGed Neurons

2002 • 496 citations

From worm to man: three subfamilies of TRP channels

2000 • 490 citations

A dual mechanosensory and chemosensory neuron in Caenorhabditis elegans.

1993 • 460 citations

Identification of a Drosophila gene encoding a calmodulin-binding protein with homology to the trp phototransduction gene

1992 • 441 citations

Mutations in a Cyclic Nucleotide–Gated Channel Lead to Abnormal Thermosensation and Chemosensation in C. elegans

1996 • 441 citations

Reprogramming Chemotaxis Responses: Sensory Neurons Define Olfactory Preferences in C. elegans

1997 • 440 citations

A Putative Cyclic Nucleotide–Gated Channel Is Required for Sensory Development and Function in C. elegans

1996 • 439 citations

Immunocyte Ca ²⁺ Influx System Mediated by LTRPC2

2001 • 434 citations

Synaptic code for sensory modalities revealed by C. elegans GLR-1 glutamate receptor

1995 • 423 citations

Polyunsaturated fatty acids activate the Drosophila light-sensitive channels TRP and TRPL

1999 • 400 citations

The Drosophila Light-Activated Conductance Is Composed of the Two Channels TRP and TRPL

1996 • 368 citations

Odorant-specific adaptation pathways generate olfactory plasticity in C. elegans

1995 • 357 citations

EAT-4, a Homolog of a Mammalian Sodium-Dependent Inorganic Phosphate Cotransporter, Is Necessary for Glutamatergic Neurotransmission inCaenorhabditis elegans

1999 • 349 citations

Mechanosensory signalling in C. elegans mediated by the GLR-1 glutamate receptor

1995 • 341 citations

A Transmembrane Guanylyl Cyclase (DAF-11) and Hsp90 (DAF-21) Regulate a Common Set of Chemosensory Behaviors in Caenorhabditis elegans

2000 • 332 citations

The GATA-factor elt-2 is essential for formation of the Caenorhabditis elegans intestine

1998 • 323 citations

The Gα Protein ODR-3 Mediates Olfactory and Nociceptive Function and Controls Cilium Morphogenesis in C. elegans Olfactory Neurons

1998 • 318 citations

C. elegans Responds to Chemical Repellents by Integrating Sensory Inputs from the Head and the Tail

2002 • 306 citations

Requirement for the PDZ Domain Protein, INAD, for Localization of the TRP Store-Operated Channel to a Signaling Complex

1997 • 292 citations

Neuronal Control of Locomotion in C. elegans Is Modified by a Dominant Mutation in the GLR-1 Ionotropic Glutamate Receptor

1999 • 291 citations

Target-selected gene inactivation in Caenorhabditis elegans by using a frozen transposon insertion mutant bank.

1993 • 278 citations

Differential expression of glutamate receptor subunits in the nervous system of Caenorhabditis elegans and their regulation by the homeodomain protein UNC-42.

2001 • 265 citations

Olfaction and Odor Discrimination Are Mediated by the C. elegans Guanylyl Cyclase ODR-1

2000 • 257 citations

Regulation of the TRP Ca2+ Channel by INAD in Drosophila Photoreceptors

1996 • 256 citations

The Caenorhabditis elegans locus lin-15, a negative regulator of a tyrosine kinase signaling pathway, encodes two different proteins.

1994 • 254 citations

Differential Expression of Glutamate Receptor Subunits in the Nervous System ofCaenorhabditis elegansand Their Regulation by the Homeodomain Protein UNC-42

2001 • 246 citations

Rescue of the Drosophila Phototransduction Mutation trp by Germline Transformation

1985 • 230 citations

The transient receptor potential protein (Trp), a putative store-operated Ca2+ channel essential for phosphoinositide-mediated photoreception, forms a signaling complex with NorpA, InaC and InaD.

1996 • 212 citations

Diverse Trafficking Patterns Due to Multiple Traffic Motifs in G Protein-Activated Inwardly Rectifying Potassium Channels from Brain and Heart

2002 • 209 citations

Calmodulin Regulation of Drosophila Light-Activated Channels and Receptor Function Mediates Termination of the Light Response In Vivo

1997 • 192 citations

Thermal avoidance in Caenorhabditis elegans : An approach to the study of nociception

1999 • 188 citations

Signal Transduction in Drosophila Photoreceptors

1995 • 178 citations

Distinct Signaling Pathways Mediate Touch and Osmosensory Responses in a Polymodal Sensory Neuron

1999 • 171 citations

TRP and the PDZ Protein, Inad, Form the Core Complex Required for Retention of the Signalplex in Drosophila Photoreceptor Cells

2000 • 170 citations

TRPγ, a Drosophila TRP–Related Subunit, Forms a Regulated Cation Channel with TRPL

2000 • 151 citations

Light-Regulated Subcellular Translocation of Drosophila TRPL Channels Induces Long-Term Adaptation and Modifies the Light-Induced Current

2002 • 143 citations

Trimethylpsoralen induces small deletion mutations inCaenorhabditis elegans.

1994 • 119 citations

Functional reconstitution of a heteromeric cyclic nucleotide-gated channel of Caenorhabditis elegans in cultured cells

1999 • 108 citations

Independent Anchoring and Assembly Mechanisms of INAD Signaling Complexes inDrosophilaPhotoreceptors

2001 • 87 citations