Role of Rho protein in lovastatin-induced breakdown of actin cytoskeleton.

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

Regulation of the mevalonate pathway

1990 • 5,282 citations

The Regulation of Rabbit Skeletal Muscle Contraction

1971 • 4,491 citations

Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

1995 • 4,387 citations

Regulation of Myosin Phosphatase by Rho and Rho-Associated Kinase (Rho-Kinase)

1996 • 2,843 citations

Phosphorylation and Activation of Myosin by Rho-associated Kinase (Rho-kinase)

1996 • 1,964 citations

Rho-stimulated contractility drives the formation of stress fibers and focal adhesions.

1996 • 1,614 citations

A brain serine/threonine protein kinase activated by Cdc42 and Rac1

1994 • 1,520 citations

The Rho family GTPases RhoA, Racl , and CDC42Hsregulate transcriptional activation by SRF

1995 • 1,280 citations

Rho-associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho.

1996 • 1,045 citations

The Ras-Related Protein Cdc42Hs and Bradykinin Promote Formation of Peripheral Actin Microspikes and Filopodia in Swiss 3T3 Fibroblasts

1995 • 1,033 citations

Glucosylation of Rho proteins by Clostridium difficile toxin B

1995 • 1,025 citations

HMG-CoA Reductase Inhibitors for Treatment of Hypercholesterolemia

1988 • 760 citations

Microinjection of recombinant p21rho induces rapid changes in cell morphology.

1990 • 720 citations

Head to tail polymerization of actin

1976 • 692 citations

Activation of Rac1, RhoA, and Mitogen-Activated Protein Kinases Is Required for Ras Transformation

1995 • 683 citations

The small GTP-binding protein Rho regulates a phosphatidylinositol 4-phosphate 5-kinase in mammalian cells

1994 • 647 citations

Selective assay of monomeric and filamentous actin in cell extracts, using inhibition of deoxyribonuclease I

1978 • 564 citations

Gln 63 of Rho is deamidated by Escherichia coli cytotoxic necrotizing factor-1

1997 • 531 citations

The mammalian G protein rhoC is ADP-ribosylated by Clostridium botulinum exoenzyme C3 and affects actin microfilaments in Vero cells.

1989 • 529 citations

Botulinum C2 toxin ADP-ribosylates actin

1986 • 503 citations

Post-translational modifications of p21rho proteins.

1992 • 422 citations

Protein Kinase N (PKN) and PKN-Related Protein Rhophilin as Targets of Small GTPase Rho

1996 • 384 citations

Feedback Regulation of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase in Livers of Mice Treated with Mevinolin, a Competitive Inhibitor of the Reductase

1980 • 305 citations

Essential role for mevalonate synthesis in DNA replication

1979 • 297 citations

Rho: a connection between membrane receptor signalling and the cytoskeleton

1996 • 271 citations

Activation of rat liver phospholipase D by the small GTP-binding protein RhoA

1994 • 265 citations

A dual functional signal mediator showing RhoGAP and phospholipase C-delta stimulating activities.

1995 • 212 citations

Activation of platelet phosphatidylinositide 3-kinase requires the small GTP-binding protein Rho.

1993 • 211 citations

Purification and characterization of two components of botulinum C2 toxin

1980 • 210 citations

Clostridium difficile toxin B acts on the GTP-binding protein Rho.

1994 • 204 citations

Post-translational modifications of the C-terminal region of the rho protein are important for its interaction with membranes and the stimulatory and inhibitory GDP/GTP exchange proteins.

1991 • 195 citations

Cytotoxic necrotizing factor type 2 produced by virulent Escherichia coli modifies the small GTP-binding proteins Rho involved in assembly of actin stress fibers.

1994 • 193 citations

Induction of phagocytic behaviour in human epithelial cells by Escherichia coli cytotoxic necrotizing factor type1

1993 • 175 citations

CAAX Geranylgeranyl Transferase Transfers Farnesyl as Efficiently as Geranylgeranyl to RhoB

1995 • 163 citations

Botulinum ADP‐ribosyltransferase C3

1988 • 162 citations

Purification of the 22 kDa protein substrate of botulinum ADP‐ribosyltransferase C3 from porcine brain cytosol and its characterization as a GTP‐binding protein highly homologous to the rho gene product

1989 • 139 citations

Clostridium botulinum C3 ADP-Ribosyltransferase

1992 • 136 citations

Isolation and nucleotide sequence of the gene encoding cytotoxic necrotizing factor 1 of Escherichia coli

1993 • 135 citations

ADP-ribosylation of actin by clostridial toxins.

1989 • 133 citations

Regulation of intracellular actin polymerization by prenylated cellular proteins

1992 • 119 citations

Adenosine diphosphate-ribosylation of G-actin by botulinum C2 toxin increases endothelial permeability in vitro.

1991 • 70 citations

A study of the Influence of mevalonic acid and its metabolites on the morphology of swiss 3T3 cells.

1982 • 70 citations

Mevalonate controls cytoskeleton organization and cell morphology in thyroid epithelial cells

1993 • 52 citations

p23rab2, a ras-like GTPase with a -GGGCC C-terminus, is isoprenylated but not detectably carboxymethylated in NIH3T3 cells.

1992 • 35 citations

Role of isoprenoid metabolism in IgE receptor-mediated signal transduction.

1991 • 31 citations

Morphological alteration of Xenopus oocytes induced by valine‐14 p21^rho depend on isoprenylation and are inhibited by Clostridium botulinum C3 ADP‐ribosyltranferase

1990 • 28 citations

GTP‐blot Analysis of Small GTP‐binding Proteins

1994 • 17 citations

Effect of in vivo and in vitro Lovastatin Treatment on Mast Cell Activation

1995 • 9 citations

Expression of a 24 kDa GTP-binding protein (Gn24) is increased in lovastatin treated human erythroleukemia cells

1996 • 6 citations