Linear 2' O-Methyl RNA probes for the visualization of RNA in living cells

Molecular Beacons: Probes that Fluoresce upon Hybridization

1996 • 4,073 citations

Localization of ASH1 mRNA Particles in Living Yeast

1998 • 1,566 citations

Multicolor molecular beacons for allele discrimination

1998 • 1,322 citations

High mobility of proteins in the mammalian cell nucleus

2000 • 1,163 citations

Structure and Function in the Nucleus

1998 • 925 citations

Dynamics of DNA Replication Factories in Living Cells

2000 • 572 citations

Function and synthesis of small nucleolar RNAs

1997 • 454 citations

Highly localized tracks of specific transcripts within interphase nuclei visualized by in situ hybridization

1989 • 434 citations

Structure of spliceosomal snRNPs and their role in pre-mRNA splicing

1990 • 407 citations

Transcription-dependent colocalization of the U1, U2, U4/U6, and U5 snRNPs in coiled bodies

1992 • 402 citations

Real time detection of DNA⋅RNA hybridization in living cells

1998 • 369 citations

Intracellular distribution of microinjected antisense oligonucleotides.

1991 • 362 citations

Structure and dynamics of human interphase chromosome territories in vivo

1998 • 333 citations

Transport and Localization Elements in Myelin Basic Protein mRNA

1997 • 307 citations

Visualization of gene activity in living cells

2000 • 305 citations

Peptide nucleic acid (PNA). A DNA mimic with a peptide backbone

1994 • 304 citations

CaMKIIα 3′ Untranslated Region-Directed mRNA Translocation in Living Neurons: Visualization by GFP Linkage

2000 • 263 citations

Spatial Relationship between Transcription Sites and Chromosome Territories

1999 • 250 citations

Intracellular disposition and metabolism of fluorescently-labled unmodified and modified oligouncleotides microijjected into mammalian cells

1993 • 239 citations

In vivo analysis of the stability and transport of nuclear poly(A)+ RNA.

1994 • 233 citations

Characterization of a Potent and Specific Class of Antisense Oligonucleotide Inhibitor of Human Protein Kinase C-α Expression

1999 • 222 citations

Localization and anchoring of mRNA in budding yeast

1999 • 219 citations

Cell biology of transcription and pre-mRNA splicing: nuclear architecture meets nuclear function

2000 • 218 citations

Advantages of 2'-O-methyl oligoribonucleotide probes for detecting RNA targets

1998 • 206 citations

Movement of nuclear poly(A) RNA throughout the interchromatin space in living cells

1999 • 190 citations

In vivo detection of snRNP-rich organelles in the nuclei of mammalian cells.

1991 • 167 citations

Rapid nuclear accumulation of injected oligodeoxyribonucleotides.

1990 • 157 citations

The travels of mRNAs through all cells large and small

1999 • 157 citations

Direct Observation of Specific Messenger RNA in a Single Living Cell under a Fluorescence Microscope

2000 • 146 citations

Mutational Analysis of Fibrillarin and Its Mobility in Living Human Cells

2000 • 141 citations

Inhibition of human telomerase by 2′- O -methyl-RNA

1998 • 139 citations

Using Molecular Beacons To Probe Molecular Interactions between Lactate Dehydrogenase and Single-Stranded DNA

2000 • 137 citations

2'-O-alkyl oligoribonucleotides as antisense probes.

1990 • 130 citations

Quantitative Digital Analysis of Diffuse and Concentrated Nuclear Distributions of Nascent Transcripts, SC35 and Poly(A)

1997 • 114 citations

In situ visualization of messenger RNA for basic fibroblast growth factor in living cells

1998 • 112 citations

Methods for visualizing RNA processing and transport pathways in living cells

2000 • 106 citations

Intracellular oligonucleotide hybridization detected by fluorescence resonance energy transfer (FRET)

1994 • 100 citations

Nuclear organization of pre-mRNA splicing factors

1999 • 89 citations

Methodologies for specific intron and exon RNA localization in cultured cells by haptenized and fluorochromized probes

1993 • 68 citations

Localisation of splicing snRNPs in mammalian cells

1993 • 67 citations

Peptide nucleic acid (PNA)

2006 • 55 citations

Inhibition of telomerase by 2'-O-(2-methoxyethyl) RNA oligomers: effect of length, phosphorothioate substitution and time inside cells

2001 • 53 citations

Fluorescence in situ hybridization using horseradish peroxidase-labeled oligodeoxynucleotides and tyramide signal amplification for sensitive DNA and mRNA detection

1998 • 50 citations

Real-time monitoring of in vitro transcriptional RNA synthesis using fluorescence resonance energy transfer

2000 • 49 citations

Establishment of a rat cell line inducible for the expression of human cytomegalovirus immediate-early gene products by protein synthesis inhibition

1986 • 45 citations

Splicing factors associate with nuclear HCMV-IE transcripts after transcriptional activation of the gene, but dissociate upon transcription inhibition: evidence for a dynamic organization of splicing factors

1997 • 45 citations

Synthesis, Processing, and Transport of RNA within the Three-Dimensional Context of the Cell Nucleus

1999 • 29 citations

Fluorescent RNA cytochemistry: tracking gene transcripts in living cells

2001 • 26 citations

Movement and localization of RNA in the cell nucleus

1999 • 23 citations

The nuclear export signal-dependent localization of oligonucleopeptides enhances the inhibition of the protein expression from a gene transcribed in cytosol

1999 • 13 citations

Specific detection of RNA molecules by fluorescent in situ hybridization in living cells

1996 • 6 citations

50 Specific detection of RNA molecules by fluorescent in situ hybridization in living cells

1996 • 1 citations