DNA elements of the type 1 adenylyl cyclase gene locus enhance reporter gene expression in neurons and pinealocytes

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

A new method for sequencing DNA.

1977 • 7,941 citations

Equilibria and kinetics of lac repressor-operator interactions by polyacrylamide gel electrophoresis

1981 • 2,828 citations

Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat.

1996 • 2,130 citations

DNAase footprinting a simple method for the detection of protein-DNA binding specificity

1978 • 2,092 citations

Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor

1995 • 2,059 citations

A gel electrophoresis method for quantifying the binding of proteins to specific DNA regions: application to components of the Escherichia coli lactose operon regulatory system

1981 • 1,991 citations

Role of the CLOCK Protein in the Mammalian Circadian Mechanism

1998 • 1,915 citations

Differential expression and activation of a family of murine peroxisome proliferator-activated receptors.

1994 • 1,410 citations

Tissue-specific in vitro transcription from the mouse albumin promoter

1986 • 1,322 citations

The Neuron-Restrictive Silencer Factor (NRSF): A Coordinate Repressor of Multiple Neuron-Specific Genes

1995 • 1,078 citations

REST: A mammalian silencer protein that restricts sodium channel gene expression to neurons

1995 • 1,078 citations

Adenylyl Cyclase Amino Acid Sequence: Possible Channel- or Transporter-Like Structure

1989 • 745 citations

Basic helix-loop-helix genes in neural development

1997 • 521 citations

Calcium-Stimulated Adenylyl Cyclase Activity Is Critical for Hippocampus-Dependent Long-Term Memory and Late Phase LTP

1999 • 482 citations

Disruption of the nuclear hormone receptor RORα in staggerer mice

1996 • 478 citations

A common silencer element in the SCG10 and type II Na+ channel genes binds a factor present in nonneuronal cells but not in neuronal cells

1992 • 420 citations

Altered behavior and long-term potentiation in type I adenylyl cyclase mutant mice.

1995 • 375 citations

Helix-loop-helix factors in growth and differentiation of the vertebrate nervous system

1997 • 364 citations

Distribution of mRNA for the calmodulin-sensitive adenylate cyclase in rat brain: Expression in areas associated with learning and memory

1991 • 269 citations

Postsynaptic alpha-adrenergic receptors potentiate the beta-adrenergic stimulation of pineal serotonin N-acetyltransferase.

1983 • 263 citations

Hippocampal neurotoxicity of Delta9-tetrahydrocannabinol.

1998 • 237 citations

Neuron-specific expression of the rat brain type II sodium channel gene is directed by upstream regulatory elements

1990 • 227 citations

Hippocampal Neurotoxicity of Δ⁹-Tetrahydrocannabinol

1998 • 217 citations

A cell type-preferred silencer element that controls the neural-specific expression of the SCG10 gene

1990 • 191 citations

Type I Adenylyl Cyclase Mutant Mice Have Impaired Mossy Fiber Long-Term Potentiation

1998 • 190 citations

Anomalous placement of introns in a member of the intermediate filament multigene family: an evolutionary conundrum.

1986 • 165 citations

An amino-terminal fragment of lac repressor binds specifically to lac operator

1978 • 164 citations

Loss of adenylyl cyclase I activity disrupts patterning of mouse somatosensory cortex

1998 • 162 citations

Impaired Cerebellar Long-Term Potentiation in Type I Adenylyl Cyclase Mutant Mice

1998 • 161 citations

Synergistic activation of the type I adenylyl cyclase by Ca2+ and Gs-coupled receptors in vivo.

1994 • 161 citations

Structure of the gene encoding Peripherin, an NGF-regulated neuronal-specific type III intermediate filament protein

1989 • 146 citations

Calmodulin-regulated adenylyl cyclases and neuromodulation

1997 • 138 citations

Calcium and muscarinic agonist stimulation of type I adenylylcyclase in whole cells.

1992 • 138 citations

The neuron-restrictive silencer element: A dual enhancer/silencer crucial for patterned expression of a nicotinic receptor gene in the brain

1997 • 134 citations

Transcriptional Regulation of the GluR2 Gene: Neural-Specific Expression, Multiple Promoters, and Regulatory Elements

1998 • 128 citations

The 5'-flanking region of the synapsin I gene. A G+C-rich, TATA- and CAAT-less, phylogenetically conserved sequence with cell type-specific promoter function.

1990 • 125 citations

Determinants of Target Gene Specificity for RORα1: Monomeric DNA Binding by an Orphan Nuclear Receptor

1995 • 121 citations

Transcriptional regulation of the GluR2 gene: Neural-specific expression, multiple promoters, and regulatory elements

1998 • 97 citations

NF-kappa B activates the HIV promoter in neurons.

1993 • 85 citations

Differentiation and DNA contact points of host proteins binding at the cis site for virion-mediated induction of alpha genes of herpes simplex virus 1

1988 • 66 citations

Developmentally Expressed Ca2+-sensitive Adenylyl Cyclase Activity Is Disrupted in the Brains of Type I Adenylyl Cyclase Mutant Mice

1995 • 60 citations

Diurnal variation of the adenylyl cyclase type 1 in the rat pineal gland.

1996 • 60 citations

Delayed secondary glucocorticoid response elements. Unusual nucleotide motifs specify glucocorticoid receptor binding to transcribed regions of alpha 2u-globulin DNA.

1991 • 53 citations

Neuron-specific expression of the synapsin II gene is directed by a specific core promoter and upstream regulatory elements

1994 • 53 citations

Identification and characterization of the GC-rich and cyclic adenosine 3',5'-monophosphate (cAMP)-inducible promoter of the type II beta cAMP-dependent protein kinase regulatory subunit gene.

1992 • 33 citations

Isolation and Characterization of the 5′-Upstream Region of the Human N-type Calcium Channel α1B Subunit Gene

1997 • 17 citations

The 5’-Flanking Region of the Synapsin I Gene

2001 • 17 citations