Anomalous placement of introns in a member of the intermediate filament multigene family: an evolutionary conundrum.

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

Cloning in single-stranded bacteriophage as an aid to rapid DNA sequencing

1980 • 3,476 citations

Why genes in pieces?

1978 • 2,256 citations

The isolation of structural genes from libraries of eucaryotic DNA

1978 • 1,877 citations

The structure and evolution of the human β-globin gene family

1980 • 1,398 citations

A mew computer method for the storage and manipulation of DNA gel reading data

1980 • 679 citations

Human metallothionein genes—primary structure of the metallothionein-II gene and a related processed gene

1982 • 464 citations

The amino acid sequence of chicken muscle desmin provides a common structural model for intermediate filament proteins.

1982 • 432 citations

Neurofilament architecture combines structural principles of intermediate filaments with carboxy-terminal extensions increasing in size between triplet proteins.

1983 • 361 citations

Muscle development--molecular and cellular control

1982 • 344 citations

Organization of the constant-region gene family of the mouse immunoglobulin heavy chain

1982 • 323 citations

The actin genes of drosophila: Protein coding regions are highly conserved but intron positions are not

1981 • 322 citations

Evolutionary history of a multigene family: An expressed human β-tubulin gene and three processed pseudogenes

1983 • 287 citations

The sequences of an expressed rat α-tubulin gene and a pseudogene with an inserted repetitive element

1982 • 260 citations

RNA-Mediated Gene Duplication: the Rat Preproinsulin I Gene Is a Functional Retroposon

1985 • 256 citations

Protein structural domains in the Caenorhabditis elegans unc-54 myosin heavy chain gene are not separated by introns.

1983 • 230 citations

The structure of the vimentin gene

1983 • 227 citations

Genetics, evolution, and expression of the 68,000-mol-wt neurofilament protein: isolation of a cloned cDNA probe.

1985 • 188 citations

The complete nucleotide sequence of the chick a-actin gene and its evolutionary relationship to the actin gene family

1982 • 183 citations

Remarkable conservation of structure among intermediate filament genes

1984 • 169 citations

RNA-mediated gene duplication: the rat preproinsulin I gene is a functional retroposon.

1985 • 153 citations

Structure of the mouse glial fibrillary acidic protein gene: implications for the evolution of the intermediate filament multigene family

1985 • 138 citations

The sequence of a type II keratin gene expressed in human skin: conservation of structure among all intermediate filament genes.

1985 • 128 citations

Characterization of the hamster desmin gene: Expression and formation of desmin filaments in nonmuscle cells after gene transfer

1985 • 112 citations

Hybrid character of a large neurofilament protein (NF-M): intermediate filament type sequence followed by a long and acidic carboxy-terminal extension.

1984 • 110 citations

Protein-chemical characterization of NF-H, the largest mammalian neurofilament component; intermediate filament-type sequences followed by a unique carboxy-terminal extension

1985 • 110 citations

Function and Evolution of Neurofilament Proteins^a

1985 • 101 citations

Characterization of globin domains: Heme binding to the central exon product

1980 • 100 citations

Unraveling the structure of the intermediate filaments

1983 • 99 citations

The complete amino acid sequence of the major mammalian neurofilament protein (NF‐L)

1985 • 93 citations

Structure of a human smooth muscle actin gene (aortic type) with a unique intron site.

1984 • 91 citations

Mouse Cμ heavy chain immunoglobulin gene segment contains three intervening sequences separating domains

1980 • 65 citations

On the Origin of Introns

1982 • 23 citations

Tubulin genes and the diversity of microtubule function.

1984 • 19 citations

Structure of a Human Smooth Muscle Actin Gene (Aortic Type) with a Unique Intron Site

1984 • 19 citations

Characterization of globin domains: Heme binding to the central exon product

1980 • 6 citations