Soluble Receptor-Induced Retroviral Infection of Receptor-Deficient Cells

The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain

1986 • 2,020 citations

Core Structure of gp41 from the HIV Envelope Glycoprotein

1997 • 1,904 citations

Atomic structure of the ectodomain from HIV-1 gp41

1997 • 1,610 citations

The HIV-1 Envelope Glycoproteins: Fusogens, Antigens, and Immunogens

1998 • 1,595 citations

Structure of influenza haemagglutinin at the pH of membrane fusion

1994 • 1,546 citations

Transfer of purified herpes virus thymidine kinase gene to cultured mouse cells

1977 • 1,411 citations

CD4-Independent Infection by HIV-2 Is Mediated by Fusin/CXCR4

1996 • 669 citations

Cell fusion by Semliki Forest, influenza, and vesicular stomatitis viruses.

1981 • 569 citations

soluble form of CD4 (T4) protein inhibits AIDS virus infection

1988 • 530 citations

Viral and Cellular Membrane Fusion Proteins

1990 • 517 citations

Cell-induced conformational change in poliovirus: externalization of the amino terminus of VP1 is responsible for liposome binding

1990 • 497 citations

HIV infection is blocked in vitro by recombinant soluble CD4

1988 • 446 citations

A soluble CD4 protein selectively inhibits HIV replication and syncytium formation

1988 • 425 citations

Soluble CD4 molecules neutralize human immunodeficiency virus type 1

1988 • 403 citations

Crystal Structure of the Ebola Virus Membrane Fusion Subunit, GP2, from the Envelope Glycoprotein Ectodomain

1998 • 387 citations

Characterization of Ebola Virus Entry by Using Pseudotyped Viruses: Identification of Receptor-Deficient Cell Lines

1998 • 358 citations

Enhancement and inhibition of avian sarcoma viruses by polycations and polyanions

1969 • 351 citations

A receptor for subgroup A Rous sarcoma virus is related to the low density lipoprotein receptor

1993 • 351 citations

Membrane fusion activity of the influenza virus hemagglutinin. The low pH-induced conformational change.

1985 • 341 citations

Membrane fusion mediated by the influenza virus hemagglutinin requires the concerted action of at least three hemagglutinin trimers.

1996 • 341 citations

Retrovirus envelope domain at 1.7 Å resolution

1996 • 315 citations

Glycoprotein D of herpes simplex virus (HSV) binds directly to HVEM, a member of the tumor necrosis factor receptor superfamily and a mediator of HSV entry

1997 • 282 citations

CD4-independent, CCR5-dependent infection of brain capillary endothelial cells by a neurovirulent simian immunodeficiency virus strain

1997 • 264 citations

The HA2 subunit of influenza hemagglutinin inserts into the target membrane prior to fusion.

1991 • 186 citations

HIV requires multiple gp120 molecules for CD4-mediated infection

1990 • 179 citations

Direct measurement of soluble CD4 binding to human immunodeficiency virus type 1 virions: gp120 dissociation and its implications for virus-cell binding and fusion reactions and their neutralization by soluble CD4

1991 • 178 citations

Human immunodeficiency virus type 2 infection and fusion of CD4-negative human cell lines: induction and enhancement by soluble CD4

1992 • 173 citations

Oligomeric structure of a prototype retrovirus glycoprotein.

1988 • 155 citations

Chemokine Receptors and HIV-1: An Attractive Pair?

1996 • 146 citations

The ectodomain of HIV-1 env subunit gp41 forms a soluble, alpha-helical, rod-like oligomer in the absence of gp120 and the N-terminal fusion peptide.

1996 • 140 citations

Enhancement of SIV Infection with Soluble Receptor Molecules

1990 • 136 citations

The poliovirus 135S particle is infectious

1996 • 135 citations

Activation of a Retroviral Membrane Fusion Protein: Soluble Receptor-induced Liposome Binding of the ALSV Envelope Glycoprotein

1997 • 118 citations

How Do Viruses Enter Cells? The HIV Coreceptors Teach Us a Lesson of Complexity

1997 • 110 citations

Receptor-triggered membrane association of a model retroviral glycoprotein

1998 • 93 citations

Targeting of HIV- and SIV-Infected Cells by CD4-Chemokine Receptor Pseudotypes

1997 • 92 citations

Receptor-induced conformational changes in the subgroup A avian leukosis and sarcoma virus envelope glycoprotein

1995 • 85 citations

Characterization of Poliovirus Conformational Alteration Mediated by Soluble Cell Receptors

1993 • 79 citations

Dissection of a retrovirus envelope protein reveals structural similarity to influenza hemagglutinin

1995 • 74 citations

Cell entry by measles virus: long hybrid receptors uncouple binding from membrane fusion

1996 • 71 citations

Analysis of the subgroup A avian sarcoma and leukosis virus receptor: the 40-residue, cysteine-rich, low-density lipoprotein receptor repeat motif of Tva is sufficient to mediate viral entry

1995 • 71 citations

Assembly of a rod-shaped chimera of a trimeric GCN4 zipper and the HIV-1 gp41 ectodomain expressed in Escherichia coli

1997 • 67 citations

Cell-specific viral targeting mediated by a soluble retroviral receptor-ligand fusion protein

1998 • 67 citations

Fusion of Rous sarcoma virus with host cells does not require exposure to low pH

1990 • 66 citations

Stimulation of glycoprotein gp120 dissociation from the envelope glycoprotein complex of human immunodeficiency virus type 1 by soluble CD4 and CD4 peptide derivatives: implications for the role of the complementarity-determining region 3-like region in membrane fusion.

1991 • 63 citations

The receptor for the subgroup A avian leukosis-sarcoma viruses binds to subgroup A but not to subgroup C envelope glycoprotein

1994 • 62 citations

Improved detection of replication-competent retrovirus

1996 • 53 citations

Soluble CD4 enhances simian immunodeficiency virus SIVagm infection

1990 • 48 citations

Production and Characterization of a Soluble, Active Form of Tva, the Subgroup A Avian Sarcoma and Leukosis Virus Receptor

1999 • 43 citations

Genetic Mapping of the Cloned Subgroup A Avian Sarcoma and Leukosis Virus Receptor Gene to the TVA Locus

1998 • 42 citations

Characterization of Determinants for Envelope Binding and Infection in Tva, the Subgroup A Avian Sarcoma and Leukosis Virus Receptor

1998 • 39 citations

Efficient Infection Mediated by Viral Receptors Incorporated into Retroviral Particles

1998 • 37 citations

Role of basic residues in the subgroup-determining region of the subgroup A avian sarcoma and leukosis virus envelope in receptor binding and infection

1997 • 37 citations

A soluble form of a receptor for subgroup A avian leukosis and sarcoma viruses (ALSV-A) blocks infection and binds directly to ALSV-A

1994 • 36 citations

Generation of a water-soluble oligomeric ectodomain of the Rous sarcoma virus envelope glycoprotein

1993 • 27 citations

Characterization of mouse lines transgenic with the human poliovirus receptor gene

1998 • 16 citations