A point mutation in the MET oncogene abrogates metastasis without affecting transformation

Cancer: Principles and Practice of Oncology.

1991 • 8,402 citations

SH2 domains recognize specific phosphopeptide sequences

1993 • 2,685 citations

Identification of the Hepatocyte Growth Factor Receptor As the c- met Proto-Oncogene Product

1991 • 2,230 citations

Cancer: Principles and Practice of Oncology

1994 • 1,825 citations

A rapid in vitro assay for quantitating the invasive potential of tumor cells.

1987 • 1,787 citations

Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas

1997 • 1,508 citations

Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth.

1992 • 1,345 citations

A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family

1994 • 983 citations

Molecular cloning of a new transforming gene from a chemically transformed human cell line

1984 • 966 citations

A Grb2-associated docking protein in EGF- and insulin-receptor signalling

1996 • 674 citations

Scatter factor and hepatocyte growth factor are indistinguishable ligands for the MET receptor.

1991 • 663 citations

Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis

1996 • 572 citations

Extracellular proteolytic cleavage by urokinase is required for activation of hepatocyte growth factor/scatter factor.

1992 • 571 citations

Tyrosine kinase receptor indistinguishable from the c-met protein

1989 • 496 citations

Expression of the Met/HGF receptor in normal and neoplastic human tissues.

1991 • 481 citations

Overexpression and amplification of the met/HGF receptor gene during the progression of colorectal cancer.

1995 • 447 citations

Invasiveness and metastasis of NIH 3T3 cells induced by Met-hepatocyte growth factor/scatter factor autocrine stimulation.

1994 • 363 citations

Uncoupling of Grb2 from the Met Receptor In Vivo Reveals Complex Roles in Muscle Development

1996 • 309 citations

Hepatocyte growth factor--scatter factor: mitogen, motogen, and met.

1991 • 234 citations

c-erbB-2/neu overexpression enhances metastatic potential of human lung cancer cells by induction of metastasis-associated properties

1995 • 210 citations

The motogenic and mitogenic responses to HGF are amplified by the Shc adaptor protein.

1995 • 180 citations

Specific Uncoupling of GRB2 from the Met Receptor

1996 • 156 citations

The tyrosine kinase receptors Ron and Sea control "scattering" and morphogenesis of liver progenitor cells in vitro.

1996 • 141 citations

Transformation by Oncogenes Encoding Protein Kinases Induces the Metastatic Phenotype

1987 • 136 citations

Pathways Downstream of Shc and Grb2 Are Required for Cell Transformation by the Tpr-Met Oncoprotein

1996 • 129 citations

The protooncogene c-sea encodes a transmembrane protein-tyrosine kinase related to the Met/hepatocyte growth factor/scatter factor receptor.

1993 • 123 citations

Constitutive Activation of the RON Gene Promotes Invasive Growth but Not Transformation

1996 • 91 citations

The HGF receptor family: unconventional signal transducers for invasive cell growth

1996 • 72 citations

Unwinding dosage compensation

1993 • 60 citations

The v-sea oncogene of avian erythroblastosis retrovirus S13: another member of the protein-tyrosine kinase gene family.

1989 • 60 citations