The tyrosine kinase receptors Ron and Sea control "scattering" and morphogenesis of liver progenitor cells in vitro.

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Identification of the Hepatocyte Growth Factor Receptor As the c- met Proto-Oncogene Product

1991 • 2,230 citations

Molecular cloning and expression of human hepatocyte growth factor

1989 • 2,191 citations

Improved retroviral vectors for gene transfer and expression.

1989 • 1,997 citations

Growth factor signaling by receptor tyrosine kinases

1992 • 1,450 citations

Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth.

1992 • 1,345 citations

Scatter factor is a fibroblast-derived modulator of epithelial cell mobility

1987 • 1,333 citations

Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor

1991 • 1,176 citations

SIGNALLING BY RECEPTOR TYROSINE KINASES

1993 • 1,098 citations

Cell binding function of E-cadherin is regulated by the cytoplasmic domain.

1988 • 811 citations

Hepatocyte growth factor (HGF) stimulates the tyrosine kinase activity of the receptor encoded by the proto-oncogene c-MET.

1991 • 698 citations

SH2 and SH3 domains

1993 • 697 citations

Scatter factor: molecular characteristics and effect on the invasiveness of epithelial cells.

1990 • 695 citations

Molecular cloning and sequence analysis of cDNA for human hepatocyte growth factor

1989 • 664 citations

Purification and partial characterization of hepatocyte growth factor from plasma of a patient with fulminant hepatic failure.

1988 • 657 citations

Molecular and biochemical characterization of the human trk proto-oncogene.

1989 • 600 citations

Purification and characterization of a growth factor from rat platelets for mature parenchymal hepatocytes in primary cultures.

1986 • 588 citations

Sequence of MET protooncogene cDNA has features characteristic of the tyrosine kinase family of growth-factor receptors.

1987 • 567 citations

A broad-spectrum human lung fibroblast-derived mitogen is a variant of hepatocyte growth factor.

1991 • 502 citations

Tyrosine kinase receptor indistinguishable from the c-met protein

1989 • 496 citations

Tumor-promoting phorbol esters induce angiogenesis in vitro

1985 • 470 citations

Purification and biological characterization of human hepatopoietin A, a polypeptide growth factor for hepatocytes.

1989 • 455 citations

Purification of scatter factor, a fibroblast-derived basic protein that modulates epithelial interactions and movement.

1989 • 411 citations

The basics of basal transcription by RNA polymerase II

1994 • 409 citations

The Met receptor tyrosine kinase transduces motility, proliferation, and morphogenic signals of scatter factor/hepatocyte growth factor in epithelial cells.

1993 • 409 citations

Cell lineages and oval cell progenitors in rat liver development.

1991 • 391 citations

A novel putative receptor protein tyrosine kinase of the met family.

1993 • 321 citations

RON is a heterodimeric tyrosine kinase receptor activated by the HGF homologue MSP.

1994 • 311 citations

The tyrosine-phosphorylated hepatocyte growth factor/scatter factor receptor associates with phosphatidylinositol 3-kinase.

1991 • 259 citations

Identification of the ron Gene Product as the Receptor for the Human Macrophage Stimulating Protein

1994 • 257 citations

Hepatocyte growth factor/hepatopoietin A stimulates the growth of rat kidney proximal tubule epithelial cells (RPTE), rat nonparenchymal liver cells, human melanoma cells, mouse keratinocytes and stimulates anchorage-independent growth of SV-40 transformed RPTE

1991 • 253 citations

Biological Activation of pro-HGF (Hepatocyte Growth Factor) by Urokinase Is Controlled by a Stoichiometric Reaction

1995 • 248 citations

Hepatocyte growth factor/scatter factor stimulates the Ras-guanine nucleotide exchanger

1993 • 206 citations

Met and hepatocyte growth factor/scatter factor signal transduction in normal melanocytes and melanoma cells.

1992 • 185 citations

The motogenic and mitogenic responses to HGF are amplified by the Shc adaptor protein.

1995 • 180 citations

The motility signal of scatter factor/hepatocyte growth factor mediated through the receptor tyrosine kinase met requires intracellular action of Ras.

1994 • 175 citations

Cloning, sequencing, and expression of human macrophage stimulating protein (MSP, MST1) confirms MSP as a member of the family of kringle proteins and locates the MSP gene on chromosome 3

1993 • 174 citations

A novel recognition motif for phosphatidylinositol 3-kinase binding mediates its association with the hepatocyte growth factor/scatter factor receptor.

1993 • 173 citations

Macrophage stimulating protein: purification, partial amino acid sequence, and cellular activity.

1991 • 171 citations

Inhibition of in vitro ovarian cancer cell invasion by modulation of urokinase-type plasminogen activator and cathepsin B.

1992 • 168 citations

Transfer of motogenic and invasive response to scatter factor/hepatocyte growth factor by transfection of human MET protooncogene.

1993 • 159 citations

Molecular cloning of a novel receptor tyrosine kinase gene, STK, derived from enriched hematopoietic stem cells

1994 • 146 citations

Molecular and Biochemical Characterization of the Human trk Proto-Oncogene

1989 • 124 citations

The protooncogene c-sea encodes a transmembrane protein-tyrosine kinase related to the Met/hepatocyte growth factor/scatter factor receptor.

1993 • 123 citations

Transformed cell lines susceptible or resistant to in vivo surveillance against tumorigenesis

1978 • 122 citations

The proto-oncogene RON is involved in development of epithelial, bone and neuro-endocrine tissues.

1995 • 99 citations

Macrophage-stimulating protein inhibits induction of nitric oxide production by endotoxin- or cytokine-stimulated mouse macrophages.

1994 • 89 citations

The murine stk gene product, a transmembrane protein tyrosine kinase, is a receptor for macrophage-stimulating protein.

1995 • 76 citations

Hepatocyte growth factor/scatter factor (HGF/SF), the c-met receptor and the behaviour of epithelial cells.

1993 • 66 citations

A Novel Recognition Motif for Phosphatidylinositol 3-Kinase Binding Mediates Its Association with the Hepatocyte Growth Factor/Scatter Factor Receptor

1993 • 49 citations

Hepatocyte growth factor stimulates phosphoinositide hydrolysis and mitogenesis in cultured renal epithelial cells

1993 • 31 citations

Enhancement of Spreading, Phagocytosis and Chemotaxis by Macrophage Stimulating Protein (MSP)

1980 • 22 citations

The <i>sea </i>Oncogene of the Avian Erythroblastosis Virus S13

1987 • 6 citations

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