Importance of endogenous tumor necrosis factor alpha and gamma interferon in host resistance against Pneumocystis carinii infection

Statistical principles in experimental design.

1962 • 27,228 citations

Interferon-γ: the Major Mediator of Resistance Against Toxoplasma gondii

1988 • 1,150 citations

Evidence that tumor necrosis factor has an important role in antibacterial resistance.

1989 • 422 citations

Biologic activities and mechanisms of action of tumor necrosis factor-alpha/cachectin.

1991 • 256 citations

A new model of Pneumocystis carinii infection in mice selectively depleted of helper T lymphocytes.

1990 • 250 citations

Requirement for CD4+ cells in resistance to Pneumocystis carinii pneumonia in mice.

1990 • 242 citations

Production of tumor necrosis factor during murine listeriosis.

1987 • 241 citations

Role of TNF and IL-1 in infections with Toxoplasma gondii.

1990 • 170 citations

Protective Effects of Tumor Necrosis Factor in Experimental Legionella pneumophila Infections of Mice via Activation of PMN Function

1988 • 133 citations

Reduction in intensity of Pneumocystis carinii pneumonia in mice by aerosol administration of gamma interferon

1991 • 120 citations

A role in vivo for tumor necrosis factor alpha in host defense against Chlamydia trachomatis

1990 • 113 citations

Inhibition of Chlamydia trachomatis growth by recombinant tumor necrosis factor

1988 • 108 citations

Enhanced production of murine interferon gamma by T cells generated in response to bacterial infection.

1982 • 93 citations

Gamma interferon controls Eimeria vermiformis primary infection in BALB/c mice

1989 • 90 citations

Alveolar macrophages in AIDS patients: increased spontaneous tumour necrosis factor-alpha production inPneumocystis cariniipneumonia

1990 • 87 citations

Analysis of the developmental stages of Pneumocystis carinii, in vitro.

1988 • 87 citations

Role of alveolar macrophages in lipopolysaccharide-induced neutrophil accumulation

1988 • 86 citations

Involvement of Cytokines in Determining Resistance and Acquired Immunity in Murine Tuberculosis

1991 • 78 citations

Interaction of Cytokines and Alveolar Cells with Pneumocystis carinii In Vitro

1991 • 77 citations

Production of interleukin 1 and tumour necrosis factor activities in bronchoalveolar washings following infection of mice by influenza virus

1990 • 72 citations

Role in vivo for gamma interferon in control of pneumonia caused by Chlamydia trachomatis in mice

1988 • 69 citations

Purification and Further Characterization of an Anti-Murine Interferon-γ Monoclonal Neutralizing Antibody

1986 • 65 citations

Recombinant tumor necrosis factor enhances macrophage destruction of Trypanosoma cruzi in the presence of bacterial endotoxin.

1988 • 62 citations

Augmented Induction of Interferons During Listeria monocytogenes Infection

1986 • 50 citations

Alveolar Macrophages from Patients with AIDS and AIDS-related Complex Constitutively Synthesize and Release Tumor Necrosis Factor Alpha

1991 • 50 citations

The role of activated macrophages in protection and immunopathology in tuberculosis

1990 • 36 citations

Pneumocystis carinii stimulates in vitro production of tumor necrosis factor-α by human macrophages

1991 • 35 citations

Enhanced treatment of Pneumocystis carinii pneumonia in rats with interferon-gamma and reduced doses of trimethoprim/sulfamethoxazole.

1990 • 33 citations

Production and Characterization of Anti-Murine Interferon-Gamma Sera

1983 • 29 citations

Immunopathogenesis of Pneumocystis carinii infection.

1991 • 28 citations

The Importance of Route of Infection in Determining the Extent of Exacerbation of Listeriosis by Anti-Interferon-γ Monoclonal Antibody

1991 • 5 citations