Involvement of Cytokines in Determining Resistance and Acquired Immunity in Murine Tuberculosis

The inducing role of tumor necrosis factor in the development of bactericidal granulomas during BCG infection

1989 • 1,269 citations

Cure of murine leishmaniasis with anti-interleukin 4 monoclonal antibody. Evidence for a T cell-dependent, interferon gamma-independent mechanism.

1990 • 629 citations

Requirement of endogenous interferon-gamma production for resolution of Listeria monocytogenes infection.

1985 • 555 citations

Interferon-Gamma, the Activated Macrophage, and Host Defense Against Microbial Challenge

1988 • 428 citations

Evidence that tumor necrosis factor has an important role in antibacterial resistance.

1989 • 422 citations

Administration of monoclonal anti-IFN-gamma antibodies in vivo abrogates natural resistance of C3H/HeN mice to infection with Leishmania major.

1989 • 374 citations

Gamma interferon activates human macrophages to become tumoricidal and leishmanicidal but enhances replication of macrophage-associated mycobacteria

1985 • 315 citations

Mycobacterial growth inhibition by interferon-gamma-activated bone marrow macrophages and differential susceptibility among strains of Mycobacterium tuberculosis.

1987 • 310 citations

Lymphokine and nonlymphokine mRNA levels in stimulated human T cells. Kinetics, mitogen requirements, and effects of cyclosporin A.

1986 • 293 citations

Tumor necrosis factor is involved in the T cell-independent pathway of macrophage activation in scid mice.

1989 • 275 citations

Activation of macrophages to inhibit proliferation of Mycobacterium tuberculosis: comparison of the effects of recombinant gamma-interferon on human monocytes and murine peritoneal macrophages.

1986 • 257 citations

Suppressor Adherent Cells in Human Tuberculosis

1978 • 235 citations

The role of gamma-interferon, vitamin D3 metabolites and tumour necrosis factor in the pathogenesis of tuberculosis.

1987 • 215 citations

Serum-free in vitro bioassay for the detection of tumor necrosis factor

1986 • 195 citations

Immune Mechanisms in the Pathogenesis of Pulmonary Tuberculosis

1989 • 191 citations

The effect of anti-IFN-gamma antibody on the protective effect of Lyt-2+ immune T cells against toxoplasmosis in mice.

1990 • 176 citations

Chronic infection due to Mycobacterium intracellulare in mice: association with macrophage release of prostaglandin E2 and reversal by injection of indomethacin, muramyl dipeptide, or interferon-gamma.

1986 • 145 citations

Treatment of experimental disseminated Mycobacterium avium complex infection in mice with recombinant IL-2 and tumor necrosis factor.

1989 • 125 citations

T-cell-mediated protection of mice against virulent Mycobacterium tuberculosis

1989 • 121 citations

A role in vivo for tumor necrosis factor alpha in host defense against Chlamydia trachomatis

1990 • 113 citations

Gamma interferon controls Eimeria vermiformis primary infection in BALB/c mice

1989 • 90 citations

Comparison of the effects of recombinant interleukin 6 and recombinant interleukin 1 on nonspecific resistance to infection

1989 • 72 citations

Dietary protein deficiency and Mycobacterium bovis BCG affect interleukin-2 activity in experimental pulmonary tuberculosis

1989 • 47 citations

Progress in the immunology of the mycobacterioses.

1987 • 45 citations

The role of activated macrophages in protection and immunopathology in tuberculosis

1990 • 36 citations

Mechanisms underlying the depressed production of interleukin-2 in spleen and lymph node cell cultures of mice infected with Mycobacterium bovis BCG

1986 • 23 citations

Intracellular killing of mycobacteria

1990 • 23 citations