REGULATION OF MILK LIPID SECRETION AND COMPOSITION

Lipoprotein Lipase

1989 • 970 citations

Feed and Animal Factors Influencing Milk Fat Composition

1993 • 870 citations

Multiple hormone interactions in the developmental biology of the mammary gland.

1980 • 866 citations

Expression cloning and characterization of a novel adipocyte long chain fatty acid transport protein

1994 • 854 citations

Fatty acid composition of brain, retina, and erythrocytes in breast- and formula-fed infants

1994 • 797 citations

The animal fatty acid synthase: one gene, one polypeptide, seven enzymes

1994 • 585 citations

Determinants of energy, protein, lipid, and lactose concentrations in human milk during the first 12 mo of lactation: the DARLING Study

1991 • 332 citations

Lipoprotein lipase activity of adipose and mammary tissue and plasma triglyceride in pregnant and lactating rats

1970 • 303 citations

Movement of fatty acids, fatty acid analogs, and bile acids across phospholipid bilayers

1993 • 301 citations

The composition of milk.

1983 • 287 citations

THE FATTY ACIDS OF HUMAN MILK. II. ALTERATIONS PRODUCED BY MANIPULATION OF CALORIC BALANCE AND EXCHANGE OF DIETARY FATS*†

1959 • 269 citations

Regulation of lipogenic enzyme gene expression by nutrients and hormones

1994 • 268 citations

The lipids in human milk

1996 • 265 citations

Fatty acid composition of mature human milk in Germany

1988 • 225 citations

Release of endothelial cell lipoprotein lipase by plasma lipoproteins and free fatty acids

1989 • 209 citations

Fatty acid metabolism in health and disease: the role of Δ-6-desaturase

1993 • 207 citations

Acyl-CoA-binding protein (ACBP) can mediate intermembrane acyl-CoA transport and donate acyl-CoA for β-oxidation and glycerolipid synthesis

1994 • 203 citations

Hormonal Control of Lactation

1942 • 199 citations

Plasma Growth Hormone Concentration in the Rat Determined by Radioimmunoassay: Influence of Sex, Pregnancy, Lactation, Anesthesia, Hypophysectomy and Extrasellar Pituitary Transplants

1966 • 177 citations

Maternal Versus Infant Factors Related to Breast Milk Intake and Residual Milk Volume: The DARLING Study

1991 • 176 citations

Degree of breast emptying explains changes in the fat content, but not fatty acid composition, of human milk

1993 • 175 citations

Lactational Capacity of Marginally Nourished Mothers: Relationships Between Maternal Nutritional Status and Quantity and Proximate Composition of Milk

1986 • 172 citations

The lipoprotein lipase of mammary gland and the correlation of its activity to lactation

1963 • 168 citations

n-3 and n-6 fatty acid processing and growth effects in neoplastic and non-cancerous human mammary epithelial cell lines

1994 • 156 citations

Role of Insulin in the Regulation of Mammary Synthesis of Fat and Protein

1995 • 148 citations

Clinical and Chemical Studies in Human Lactation.--VII

1954 • 139 citations

Human lactation: maternal transfer of dietary triglycerides labeled with stable isotopes

1987 • 139 citations

Lipid metabolism in the mammary gland or ruminant animals

1979 • 133 citations

Regulation of fatty acid synthase gene expression: an approach for reducing fat accumulation

1993 • 130 citations

Effect of prolactin on lipoprotein lipase in mammary glands and adipose tissue of rats

1974 • 129 citations

Bovine Milk Lipids

1995 • 128 citations

Hormonal Control of Lactation

1980 • 126 citations

The Adaptation of Milk Secretion to the Constraints of Fasting in Bears, Seals, and Baleen Whales

1993 • 123 citations

Dietary supplementation of lactating Gambian women. I. Effect on breast-milk volume and quality.

1983 • 122 citations

Clinical and Chemical Studies in Human Lactation.--I, II, and III

1954 • 118 citations

Upstream Stimulatory Factors Bind to Insulin Response Sequence of the Fatty Acid Synthase Promoter USF1 IS REGULATED

1995 • 116 citations

Sp1 Mediates Glucose Activation of the Acetyl-CoA Carboxylase Promoter

1996 • 115 citations

Differences between lactating and non-lactating dairy cows in concentration and secretion rate of insulin

1979 • 111 citations

Collection of fore and hind milk from the sow and the changes in milk composition during suckling

1992 • 107 citations

Interactions of prolactin and growth hormone (GH) in the regulation of mammary gland function and epithelial cell survival.

1997 • 106 citations

Role of Insulin in the Regulation of Milk Fat Synthesis in Dairy Cows

1997 • 105 citations

The effect of hydrogenated fat in the diet of nursing mothers on lipid composition and prostaglandin content of human milk

1984 • 103 citations

Twenty-four hour patterns of prolactin secretion during lactation and the relationship to suckling and the resumption of fertility hi breast-feeding women

1996 • 101 citations

Feedback control of milk secretion from milk

1996 • 97 citations

The role of growth hormone, prolactin and insulin-like growth factors in the regulation of rat mammary gland and adipose tissue metabolism during lactation

1992 • 96 citations

Breast-milk fat concentrations of rural African women

1981 • 95 citations

Milk Fat Depression, the Glucogenic Theory, and Trans-C18:1 Fatty Acids

1995 • 94 citations

Dietary regulation of mammary lipogenesis in lactating rats

1980 • 93 citations

Human Lactation II: Endogenous Fatty Acid Synthesis by the Mammary Gland

1989 • 91 citations

Glucose metabolism during lactation in the rat: quantitative and regulatory aspects

1983 • 86 citations

Diminution in energy expenditure during lactation.

1986 • 84 citations

The Structure of Milk: Implications for Sampling and Storage

1995 • 84 citations

Maternal anthropometric status and lactation performance in a low-income Honduran population: evidence for the role of infants

1995 • 80 citations

Effects of varying maternal dietary fatty acids in lactating women and their infants

1979 • 80 citations

Inhibitory effects of long‐chain acyl coenzyme a analogues on rat liver acetyl coenzyme a carboxylase

1979 • 78 citations

Mammary and whole animal metabolism of glucose and fatty acids in fasting lactating goats

1968 • 77 citations

Interaction of lipoprotein lipase with glycosaminoglycans and apolipoprotein C-II: Effects of free-fatty-acids

1990 • 72 citations

Identification of an Inverted CCAAT Box Motif in the Fatty-acid Synthase Gene as an Essential Element for Mediation of Transcriptional Regulation by cAMP

1996 • 71 citations

Rat Mammary Acetyl Coenzyme A Carboxylase

1969 • 70 citations

Glucose transporter expression in rat mammary gland

1990 • 69 citations

Fatty acid composition of mature human milk in Nigeria

1991 • 67 citations

Effect of Exogenous Long-Chain Fatty Acids on Individual Fatty Acid Synthesis by Dispersed Ruminant Mammary Gland Cells

1987 • 67 citations

Studies on the mode of uptake of blood triglycerides by the mammary gland of the lactating goat. The uptake and incorporation into milk fat and mammary lymph of labelled glycerol, fatty acids and triglycerides

1972 • 67 citations

Regulation of lipoprotein lipase activity and mRNA in the mammary gland of the lactating mouse

1994 • 65 citations

Effect of Exogenous Long-Chain Fatty Acids on Lipid Biosynthesis in Dispersed Ruminant Mammary Gland Epithelial Cells: Esterification of Long-Chain Exogenous Fatty Acids

1987 • 65 citations

The Composition and Biosynthesis of Milk Fat1 1Supported by grants AM 16073 and AM 17489 from the National Institute of Health and grant BMS 7412723 from the National Science Foundation.

1975 • 63 citations

Fatty acid patterns of human milk

1977 • 63 citations

Diurnal variations in food intake and in lipogenesis in mammary gland and liver of lactating rats

1983 • 61 citations

Control of fatty acid synthesis in lactation

1983 • 61 citations

Essential fatty acids in full term infants fed breast milk or formula.

1995 • 59 citations

Increased insulin sensitivity and responsiveness during lactation in rats

1986 • 58 citations

Metabolic adaptations during lactogenesis. Fatty acid synthesis in rabbit mammary tissue during pregnancy and lactation

1974 • 57 citations

Lactation performance of rural Mesoamerindians.

1992 • 57 citations

Lipoprotein lipase activity and its relationship to high milk fat transfer during lactation in grey seals

1995 • 56 citations

Acyl-CoA-binding protein (ACBP) and its relation to fatty acid-binding protein (FABP): an overview

1990 • 55 citations

Characteristics of fatty acid-binding proteins and their relation to mammary-derived growth inhibitor

1990 • 52 citations

Distribution and source of lipoprotein lipase in mouse mammary gland

1991 • 51 citations

Identification and characterization of glucose transport proteins in plasma membrane- and Golgi vesicle-enriched fractions prepared from lactating rat mammary gland

1990 • 50 citations

Effect of insulin on in vivo glucose utilization in individual tissues of anesthetized lactating rats

1987 • 50 citations

Hormonal induction of functional differentiation and mammary-derived growth inhibitor expression in cultured mouse mammary gland explants

1992 • 50 citations

Metabolic adaptations in goat mammary tissue during pregnancy and lactation

1986 • 48 citations

Effect of Feefing Protected Lipid on the Uptake of Precursors of Milk Fat by the Bovine Mammary Gland

1973 • 48 citations

Role of polyamines in mitogenic and secretory responses of pancreatic beta-cells to growth factors

1990 • 48 citations

Regulation of acetyl-CoA carboxylase in rat mammary gland. Effects of starvation and of insulin and prolactin deficiency on the fraction of the enzyme in the active form in vivo

1982 • 47 citations

Dietary fat and milk fat secretion in the cow

1968 • 46 citations

Phospholipase D-derived Products in the Regulation of 12- -Tetradecanoylphorbol-13-acetate-stimulated Prostaglandin Synthesis in Madin-Darby Canine Kidney Cells

1996 • 45 citations

Pattern and Regulation of Acetyl-CoA Carboxylase Gene Expression

1994 • 45 citations

Monosaccharide transport into lactating-rat mammary acini

1982 • 43 citations

Initiation of lipogenic enzyme activities in rat mammary glands

1981 • 42 citations

Re-examination of the putative roles of insulin and prolactin in the regulation of lipid deposition and lipogenesis in vivo in mammary gland and white and brown adipose tissue of lactating rats and litter-removed rats

1989 • 41 citations

Physiological significance of the concentration of human milk glucose

1990 • 41 citations

Milk fat synthesis.

1983 • 40 citations

Growth-hormone-prolactin interactions in the regulation of mammary and adipose-tissue acetyl-CoA carboxylase activity and gene expression in lactating rats

1992 • 40 citations

Comparison of the fatty acid composition of human milk from mothers in Tanzania, Curacao and Surinam.

1987 • 38 citations

Effect of insulin in conjunction with glucose, amino acids and potassium on net metabolism of glucose and amino acids in the goat mammary gland

1992 • 37 citations

Effect of different fatty acids on lipogenesis in rat and sheep adipose tissue in vitro

1977 • 36 citations

Lipoprotein lipase synthesis and secretion: effects of concentration and type of fatty acids in adipocyte cell culture.

1993 • 36 citations

Lipoprotein lipase in human milk: compartmentalization and effect of fasting, insulin, and glucose.

1991 • 36 citations

Inhibition of fatty acid synthesis by expression of an acetyl-CoA carboxylase-specific ribozyme gene.

1994 • 35 citations

Effects of fasting, elevated plasma glucose and plasma insulin concentrations on milk secretion in women

1993 • 34 citations

Milk lipid globules: control of their size distribution.

1988 • 34 citations

Rat mammary-gland acetyl-coenzyme A carboxylase. Interaction with milk fatty acids

1970 • 33 citations

Metabolite utilization by the ruminant mammary gland.

1983 • 33 citations

Proteins of the Milk-Fat-Globule Membrane as Markers of Mammary Epithelial Cells and Apical Plasma Membrane

1987 • 31 citations

Insulin receptor activity and insulin sensitivity in mammary gland of lactating rats

1990 • 31 citations

Chain-length dependency of interactions of medium-chain fatty acids with glucose metabolism in acini isolated from lactating rat mammary glands. A putative feed-back to control milk lipid synthesis from glucose

1992 • 29 citations

Regulation of rat mammary-gland uptake of orally administered [1-14C]triolein by insulin and prolactin: evidence for bihormonal control of lipoprotein lipase activity

1994 • 28 citations

Expression of Fatty Acid-Binding Proteins in the Developing Mouse Mammary-Gland

1993 • 28 citations

Lipoprotein lipase release from BFC-1 beta adipocytes. Effects of triglyceride-rich lipoproteins and lipolysis products.

1992 • 27 citations

Changes in mammary uptake of free fatty acids, triglyceride, cholesterol and phospholipid in relation to milk synthesis during lactation in goats

1994 • 26 citations

Interactions between Fatty Acids and Lipoprotein Lipase: Specific Binding and Complex Formation

1994 • 26 citations

Control of glucose metabolism in isolated acini of the lactating mamary gland of the rat. Effects of oleate on glucose utilization and lipogenesis

1978 • 25 citations

Regulation of Mammary Glucose Metabolism in Lactation

1987 • 25 citations

Effects of exogenous insulin or vanadate on disposal of dietary triacylglycerols between mammary gland and adipose tissue in the lactating rat: insulin resistance in white adipose tissue

1993 • 24 citations

The Composition of Milk

1974 • 24 citations

Insulin activation of lipogenesis in isolated mammary acini from lactating rats fed on a high-fat diet. Evidence that acetyl-CoA carboxylase is a site of action

1987 • 23 citations

Assessment of mammary gland metabolism in the sow: II. Cellular metabolites in the mammary secretion and plasma during lactogenesis II

1995 • 23 citations

The lactating mammary gland of the rat and the starved-refed transition: a model system for the study of the temporal regulation of substrate utilization

1990 • 21 citations

Effect of reproductive states on lipid mobilization and linoleic acid metabolism in mammary glands

1995 • 20 citations

Fatty acid desaturation by mammary gland microsomes from lactating mice

1974 • 19 citations

The effect of starvation and refeeding on lipogenic enzymes in mammary glands and livers of lactating rats

1983 • 19 citations

Effects of feeding medium-chain triacylglycerols on maternal lipid metabolism and pup growth in lactating rats

1993 • 19 citations

Stimulatory effect of glucose upon triglyceride synthesis from acetate, decanoate, and palmitate by mammary gland slices from lactating mice

1975 • 17 citations

Regulation of mouse mammary cell differentiation by extracellular milk proteins

1991 • 16 citations

Stearoyl‐coenzyme a desaturase activity in the mammary gland and liver of lactating rats

1982 • 16 citations

Mechanisms Involved in the Uptake of D-Glucose into the Milk-Producing Cells of Rat Mammary Tissue

1995 • 16 citations

Regulation by insulin of glucose metabolism in mammary gland of anaesthetized lactating rats. Stimulation of phosphofructokinase-1 by fructose 2,6-bisphosphate and activation of acetyl-CoA carboxylase

1988 • 16 citations

Glucose homoeostasis in pregnancy and lactation

1987 • 16 citations

Effect of changes in litter size at mid-lactation on lactation in rats

1984 • 15 citations

Effect of Extended Lactation and Diet on Transferrin Concentrations in Rat Milk

1988 • 15 citations

Lack of dietary adaptation of intestinal 2‐monoglyceride acyl transferase

1974 • 15 citations

Endocrine Regulation of Nutrient Flux in the Lactating Woman

1994 • 13 citations

Diurnal variations in the fatty acid composition of milk fat from marginally nourished women.

1995 • 12 citations

Role of Protein Phosphorylation in the Regulation of Fatty Acid Synthesis in the Mammary Gland of the Lactating Rat

1987 • 10 citations

Glucose Turnover Rate in the Lactating Rat: Effect of Feeding a High Fat Diet

1987 • 10 citations

Lactation in Australian women.

1980 • 10 citations

A Role for Medium-Chain Fatty Acids in the Regulation of Lipid Synthesis in Milk Stasis?

1995 • 9 citations

Regulation of Milk Fat Synthesis

1989 • 6 citations

Regulation of Milk Fat Synthesis

1989 • 5 citations

Effect of chronic consumption of a high-fat diet on mammary metabolism

1984 • 5 citations

The effect of initiated involution on enzyme activity and substrate uptake by the mammary gland of the lactating rabbit

1983 • 5 citations

Rapid inhibition by intragastric triolein of the re-activation of glucose utilization and lipogenesis in the mammary gland during the starved-refed transition in lactating rats. Evidence for a direct effect of oral lipid on mammary tissue

1988 • 5 citations

Prolactin receptors in the lactating rabbit mammary gland during initiated involution

1983 • 4 citations

Responses of glucose metabolism to insulin in perfused mammary tissue of lactating rats: influence of dietary history and recent insulin experience

1996 • 4 citations

Assessment of Lipoprotein Activators of Skim Milk Lipoprotein Lipase and the Relationship Between Lipoprotein Lipase Activity and Milk Fat Synthesis

1989 • 2 citations