Inhibition of fatty acid synthesis by expression of an acetyl-CoA carboxylase-specific ribozyme gene.

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

A very strong enhancer is located upstream of an immediate early gene of human cytomegalovirus

1985 • 1,155 citations

Simple RNA enzymes with new and highly specific endoribonuclease activities

1988 • 1,118 citations

A small catalytic oligoribonucleotide

1987 • 938 citations

Antisense RNA Inactivation of Myosin Heavy Chain Gene Expression in Dictyostelium discoideum

1987 • 677 citations

Ribozymes as Potential Anti-HIV-1 Therapeutic Agents

1990 • 663 citations

Self-cleavage of plus and minus RNAs of a virusoid and a structural model for the active sites

1987 • 660 citations

The Chemistry of Self-Splicing RNA and RNA Enzymes

1987 • 523 citations

Biological Catalysis by RNA

1986 • 496 citations

Antisense RNA of proto-oncogene c-fos blocks renewed growth of quiescent 3T3 cells.

1987 • 381 citations

Self-cleavage of virusoid RNA is performed by the proposed 55-nucleotide active site

1987 • 323 citations

Inhibition of human immunodeficiency virus replication by antisense oligodeoxynucleotides.

1988 • 227 citations

Ribozyme mediated destruction of RNA in vivo.

1989 • 223 citations

Fatty acylated proteins as components of intracellular signaling pathways

1990 • 202 citations

Regulation of the Activity of Acetyl Coenzyme A Carboxylase by Palmitoyl Coenzyme A and Citrate

1972 • 195 citations

Specific gene suppression by engineered ribozymes in monkey cells.

1989 • 171 citations

Multitarget-ribozyme directed to cleave at up to nine highly conserved HIV-1 env RNA regions inhibits HIV-1 replication—potential effectiveness against most presently sequenced HIV-1 isolates

1992 • 139 citations

Regulation of Lipid Synthesis in Cultured Animal Cells

1974 • 87 citations

Ribozymes correctly cleave a model substrate and endogenous RNA in vivo.

1990 • 82 citations

Structural features of the acetyl-CoA carboxylase gene: mechanisms for the generation of mRNAs with 5' end heterogeneity.

1989 • 79 citations

Heterogeneity at the 5′ end of rat acetyl-coenzyme A carboxylase mRNA

1989 • 71 citations

Antisense RNA of Proto-Oncogene c-fos Blocks Renewed Growth of Quiescent 3T3 Cells

1987 • 70 citations

Molecular cloning of cDNA for acetyl-coenzyme A carboxylase.

1986 • 67 citations

Ribozymes that cleave an RNA sequence from human immunodeficiency virus: The effect of flanking sequence on rate

1991 • 66 citations

Measurement of acetyl-CoA carboxylase activity in isolated hepatocytes

1987 • 64 citations

Cloning of human acetyl‐CoA carboxylase cDNA

1994 • 58 citations

Mobile RNA catalysts

1988 • 52 citations

An enhancer element in the house-keeping promoter for acetyl-CoA carboxylase gene

1990 • 50 citations

Inhibition of SV40 replicon function by engineered antisense RNA transcribed by RNA polymerase III.

1987 • 39 citations

Transcriptional regulation of acetyl coenzyme A carboxylase gene expression by tumor necrosis factor in 30A-5 preadipocytes.

1989 • 36 citations

Regulation of acetyl-CoA carboxylase gene expression. Insulin induction of acetyl-CoA carboxylase and differentiation of 30A5 preadipocytes require prior cAMP action on the gene

1991 • 27 citations

Free fatty acids associated with the high molecular weight aminoacyl-tRNA synthetase complex influence its structure and function.

1990 • 13 citations

Transcriptional Regulation of Acetyl Coenzyme A Carboxylase Gene Expression by Tumor Necrosis Factor in 30A-5 Preadipocytes

1989 • 8 citations