The integrity of the conserved ‘WS motif’ common to IL-2 and other cytokine receptors is essential for ligand binding and signal transduction.

Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

1984 • 2,762 citations

Structural design and molecular evolution of a cytokine receptor superfamily.

1990 • 2,104 citations

The human insulin receptor cDNA: The structural basis for hormone-activated transmembrane signalling

1985 • 1,485 citations

Cloning and Expression of the Human Interleukin-6 (BSF-2/IFNβ 2) Receptor

1988 • 1,063 citations

Molecular cloning and expression of cDNAs for the human interleukin-2 receptor

1984 • 858 citations

Expression cloning of the murine erythropoietin receptor

1989 • 776 citations

Expression cloning of a receptor for human granulocyte-macrophage colony-stimulating factor.

1989 • 711 citations

Interleukin-2 Receptor β Chain Gene: Generation of Three Receptor Forms by Cloned Human α and β Chain cDNA's

1989 • 680 citations

The murine interleukin-4 receptor: Molecular cloning and characterization of secreted and membrane bound forms

1989 • 645 citations

Interaction of the unique N-terminal region of tyrosine kinase p56lck with cytoplasmic domains of CD4 and CD8 is mediated by cysteine motifs

1990 • 629 citations

Novel Interleukin-2 Receptor Subunit Detected by Cross-Linking Under High-Affinity Conditions

1986 • 585 citations

Molecular cloning of cDNA encoding human interleukin-2 receptor

1984 • 567 citations

Interleukin 2 high-affinity receptor expression requires two distinct binding proteins.

1987 • 565 citations

Cloning and expression of the rat prolactin receptor, a member of the growth hormone/prolactin receptor gene family

1988 • 564 citations

A new cytokine receptor superfamily

1990 • 506 citations

Demonstration of a non-Tac peptide that binds interleukin 2: a potential participant in a multichain interleukin 2 receptor complex.

1986 • 477 citations

The CD4 and CD8 antigens are coupled to a protein-tyrosine kinase (p56lck) that phosphorylates the CD3 complex.

1989 • 447 citations

The IL-2 Receptor β Chain (p70): Role in Mediating Signals for LAK, NK, and Proliferative Activities

1987 • 444 citations

Cloning of an Interleukin-3 Receptor Gene: a Member of a Distinct Receptor Gene Family

1990 • 417 citations

A restricted cytoplasmic region of IL-2 receptor β chain is essential for growth signal transduction but not for ligand binding and internalization

1989 • 370 citations

Expression cloning of a receptor for murine granulocyte colony-stimulating factor

1990 • 362 citations

A second human interleukin-2 binding protein that may be a component of high-affinity interleukin-2 receptors

1987 • 306 citations

Cloning, sequence and expression of human interleukin-2 receptor

1984 • 272 citations

Molecular cloning and expression of the murine interleukin-5 receptor.

1990 • 227 citations

The p75 peptide is the receptor for interleukin 2 expressed on large granular lymphocytes and is responsible for the interleukin 2 activation of these cells.

1987 • 226 citations

Characterization of the interleukin 2 receptor beta chain using three distinct monoclonal antibodies.

1989 • 219 citations

The sequence and topology of human complement component C9.

1985 • 179 citations

Nucleotide sequence of cDNA and derived amino acid sequence of human complement component C9.

1984 • 160 citations

Complementary DNA and derived amino acid sequence of the .alpha. subunit of human complement protein C8: evidence for the existence of a separate .alpha. subunit messenger RNA

1987 • 112 citations

Expression cloning of a cDNA encoding the murine interleukin 4 receptor based on ligand binding.

1990 • 108 citations

Structure-Function Studies on Bacteriorhodopsin

1989 • 100 citations

The heparin-binding site of antithrombin III. Identification of a critical tryptophan in the amino acid sequence.

1984 • 99 citations

Structure of the Murine lck Gene and Its Rearrangement in a Murine Lymphoma Cell Line

1988 • 86 citations

An associated molecule, p64, eith high-affinity interleukin 2 receptor

1990 • 64 citations

The lysine binding sites of human plasminogen. Evidence for a critical tryptophan in the binding site of kringle 4.

1981 • 61 citations

Interleukin 2 receptor beta chain expressed in an oligodendroglioma line binds interleukin 2 and delivers growth signal.

1990 • 40 citations

Constitutive production of human interferons by mouse cells with bovine papillomavirus as a vector.

1984 • 40 citations

Intracytoplasmic phosphorylation sites of Tac antigen (p55) are not essential for the conformation, function, and regulation of the human interleukin 2 receptor.

1986 • 22 citations