Properties and regulation of glutamine transporter SN1 by protein kinases SGK and PKB

Mechanism of activation of protein kinase B by insulin and IGF-1.

1996 • 2,965 citations

Epithelial sodium channel regulated by aldosterone-induced protein sgk

1999 • 728 citations

Phosphorylation of Nedd4-2 by Sgk1 regulates epithelial Na+ channel cell surface expression

2001 • 699 citations

Insulin signaling pathways in time and space

2002 • 630 citations

Activation of serum- and glucocorticoid-regulated protein kinase by agonists that activate phosphatidylinositide 3-kinase is mediated by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and PDK2

1999 • 598 citations

Serum and glucocorticoid-inducible kinase (SGK) is a target of the PI 3-kinase-stimulated signaling pathway

1999 • 555 citations

Characterization of sgk, a Novel Member of the Serine/Threonine Protein Kinase Gene Family Which Is Transcriptionally Induced by Glucocorticoids and Serum

1993 • 537 citations

sgk Is an Aldosterone-induced Kinase in the Renal Collecting Duct

1999 • 452 citations

Serum and Glucocorticoid-regulated Kinase Modulates Nedd4-2-mediated Inhibition of the Epithelial Na+Channel

2002 • 451 citations

Characteristics of an amino acid transport system in rat liver for glutamine, asparagine, histidine, and closely related analogs.

1980 • 429 citations

Characterization of sgk, a novel member of the serine/threonine protein kinase gene family which is transcriptionally induced by glucocorticoids and serum.

1993 • 415 citations

Cloning and characterization of a putative human serine/threonine protein kinase transcriptionally modified during anisotonic and isotonic alterations of cell volume

1997 • 372 citations

Molecular Analysis of System N Suggests Novel Physiological Roles in Nitrogen Metabolism and Synaptic Transmission

1999 • 318 citations

Transfer of glutamine between astrocytes and neurons

2001 • 314 citations

Regulation and Physiological Roles of Serum- and Glucocorticoid-Induced Protein Kinase Isoforms

2001 • 270 citations

Glutamine Uptake by Neurons: Interaction of Protons with System A Transporters

2002 • 205 citations

The Use of Xenopus laevis Oocytes for the Functional Characterization of Heterologously Expressed Membrane Proteins

2000 • 204 citations

The glutamine commute

2002 • 198 citations

Regulation ofsgkby aldosterone and its effects on the epithelial Na⁺channel

2000 • 188 citations

Hyperosmotic Stress Stimulates Promoter Activity and Regulates Cellular Utilization of the Serum- and Glucocorticoid-inducible Protein Kinase (Sgk) by a p38 MAPK-dependent Pathway

2000 • 156 citations

The amino acid/auxin:proton symport permease family1The accompanying review paper ‘Phylogenetic characterization of novel transport protein families revealed by genome analysis’ by M.H. Saier Jr. et al. will be published in Biochim. Biophys. Acta, Vol. 1422/1, February 1999 issue.1

1999 • 149 citations

Cell‐specific expression of the glutamine transporter SN1 suggests differences in dependence on the glutamine cycle

2002 • 136 citations

IGF-1 up-regulates K+ channels via PI3-kinase, PDK1 and SGK1

2001 • 133 citations

Regulation of the glutamine transporter SN1 by extracellular pH and intracellular sodium ions

2002 • 124 citations

Regulation of the cardiac voltage‐gated Na⁺ channel (H1) by the ubiquitin‐protein ligase Nedd4

2000 • 110 citations

Coupled and uncoupled proton movement by amino acid transport system N

2001 • 106 citations

Primary Structure, Genomic Organization, and Functional and Electrogenic Characteristics of Human System N 1, a Na+- and H+-coupled Glutamine Transporter

2000 • 105 citations

Human ubiquitin‐protein ligase Nedd4: expression, subcellular localization and selective interaction with ubiquitin‐conjugating enzymes

1998 • 101 citations

The Shrinkage-activated Na<sup>+</sup> Conductance of Rat Hepatocytes and its Possible Correlation to rENaC

2000 • 98 citations

Na+ transport by the neural glutamine transporter ATA1

2001 • 87 citations

Cerebral localization and regulation of the cell volume-sensitive serum- and glucocorticoid-dependent kinase SGK1

2001 • 82 citations

Identification and characterization of an amino acid transporter expressed differentially in liver

2000 • 81 citations

K + channel activation by all three isoforms of serum- and glucocorticoid-dependent protein kinase SGK

2002 • 78 citations

Identification and characterization of an amino acid transporter expressed differentially in liver

2000 • 71 citations

Cloning of sgk serine-threonine protein kinase from shark rectal gland - a gene induced by hypertonicity and secretagogues

1998 • 70 citations

Hepatic Glutamine Transport and Metabolism

1998 • 65 citations

Hormonal regulation of amino acid transport system N in primary cultures of rat hepatocytes

1987 • 57 citations

Structure-Function Relationships of Heterodimeric Amino Acid Transporters

2002 • 54 citations

Responses of glutamine transport in cultured rat skeletal muscle to osmotically induced changes in cell volume.

1996 • 49 citations

Mechanisms of Glutamine Transport in Rat Adipocytes and Acute Regulation by Cell Swelling

2001 • 42 citations

Glucocorticoid regulation of splanchnic glutamine, alanine, glutamate, ammonia, and glutathione fluxes

1993 • 22 citations

Adaptive regulation of amino acid transport in nutrient-deprived human hepatomas

1996 • 21 citations

Characteristics of glutamine transport in primary tissue culture of rat skeletal muscle

1993 • 19 citations

Effects of insulin and exercise on amino acid transport in rat skeletal muscle

1994 • 16 citations

Insulin-like growth factor-I stimulates amino acid transport in a glutamine-deprived human neuroblastoma cell line

2001 • 9 citations