In vitro model for the nuclear transport of the hepadnavirus genome

Replication of the genome of a hepatitis B-like virus by reverse transcription of an RNA intermediate

1982 • 1,429 citations

Nuclear protein import in permeabilized mammalian cells requires soluble cytoplasmic factors.

1990 • 909 citations

The Vpr protein of human immunodeficiency virus type 1 influences nuclear localization of viral nucleic acids in nondividing host cells.

1994 • 845 citations

Stepwise dismantling of adenovirus 2 during entry into cells

1993 • 810 citations

Isolation of a protein that is essential for the first step of nuclear protein import

1994 • 710 citations

Formation of the pool of covalently closed circular viral DNA in hepadnavirus-infected cells

1986 • 652 citations

Nuclear transport of influenza virus ribonucleoproteins: The viral matrix protein (M1) promotes export and inhibits import

1991 • 559 citations

Three-dimensional structure of hepatitis B virus core particles determined by electron cryomicroscopy

1994 • 495 citations

The arginine-rich domain of the hepatitis B virus core protein is required for pregenome encapsidation and productive viral positive-strand DNA synthesis but not for virus assembly

1992 • 427 citations

Hepatitis B virus nucleocapsid assembly: primary structure requirements in the core protein

1990 • 365 citations

The two steps of nuclear import, targeting to the nuclear envelope and translocation through the nuclear pore, require different cytosolic factors

1992 • 278 citations

Replicative intermediates of hepatitis B virus in HepG2 cells that produce infectious virions

1988 • 272 citations

Hepatitis B virus contains protein attached to the 5′ terminus of its complete DNA strand

1980 • 248 citations

In hepatocytes infected with duck hepatitis B virus, the template for viral RNA synthesis is amplified by an intracellular pathway

1990 • 216 citations

RNA- and DNA-binding activities in hepatitis B virus capsid protein: a model for their roles in viral replication

1992 • 205 citations

The amino-terminal domain of the hepadnaviral P-gene encodes the terminal protein (genome-linked protein) believed to prime reverse transcription.

1988 • 198 citations

Expression of the terminal protein region of hepatitis B virus inhibits cellular responses to interferons alpha and gamma and double-stranded RNA.

1991 • 163 citations

Effect of core protein phosphorylation by protein kinase C on encapsidation of RNA within core particles of hepatitis B virus

1994 • 149 citations

Evolutionary conservation in the hepatitis B virus core structure: comparison of human and duck cores

1995 • 135 citations

The arginine-rich domain of hepatitis B virus precore and core proteins contains a signal for nuclear transport

1990 • 135 citations

Analysis of the earliest steps of hepadnavirus replication: genome repair after infectious entry into hepatocytes does not depend on viral polymerase activity

1993 • 130 citations

Hepatitis B virus capsid particles are assembled from core-protein dimer precursors.

1992 • 126 citations

Hepatitis B virus core antigen has two nuclear localization sequences in the arginine-rich carboxyl terminus

1991 • 125 citations

Protein covalently bound to minus-strand DNA intermediates of duck hepatitis B virus

1983 • 121 citations

Protein Kinase Activity in Hepatitis B Virus

1980 • 112 citations

Hepatitis B virus nucleocapsid particles do not cross the hepatocyte nuclear membrane in transgenic mice

1994 • 109 citations

Transport of hepatitis B virus precore protein into the nucleus after cleavage of its signal peptide

1989 • 93 citations

Hepatitis B Viral DNA Molecules Have Cohesive Ends

1979 • 79 citations

Specificity and localization of the hepatitis B virus-associated protein kinase

1982 • 78 citations

The Half-Life of Duck Hepatitis B Virus Supercoiled DNA in Congenitally Infected Primary Hepatocyte Cultures

1994 • 70 citations

Nuclear Import of Microinjected Influenza Virus Ribonucleoproteins

1994 • 70 citations

Biochemical and immunological characterization of the duck hepatitis B virus envelope proteins

1987 • 60 citations

A micromolar pool of antigenically distinct precursors is required to initiate cooperative assembly of hepatitis B virus capsids in Xenopus oocytes

1993 • 57 citations

Assay of hepatitis B viras genome titers in sera of infected subjects

1986 • 48 citations

Expression of the P-protein of the human hepatitis B virus in a vaccinia virus system and detection of the nucleocapsid-associated P-gene product by radiolabelling at newly introduced phosphorylation sites

1992 • 41 citations

Adsorption and Penetration of Hepatitis B Virus in a Nonpermissive Cell Line

1994 • 38 citations

Antiviral strategies in chronic hepatitis B virus infection: I. Establishment of an in vitro system using the duck hepatitis B virus model

1990 • 30 citations

Characterization of the endogenous protein kinase activity of the hepatitis B virus

1993 • 27 citations