Does transcription by RNA polymerase play a direct role in the initiation of replication?

A major developmental transition in early xenopus embryos: I. characterization and timing of cellular changes at the midblastula stage

1982 • 1,635 citations

A major developmental transition in early xenopus embryos: II. control of the onset of transcription

1982 • 1,065 citations

A cellular DNA-binding protein that activates eukaryotic transcription and DNA replication

1987 • 1,050 citations

Visualization of focal sites of transcription within human nuclei.

1993 • 656 citations

A Yeast Chromosomal Origin of DNA Replication Defined by Multiple Functional Elements

1992 • 634 citations

Simian virus 40 DNA replication in vitro.

1984 • 562 citations

Fluorescent labeling of nascent RNA reveals transcription by RNA polymerase II in domains scattered throughout the nucleus

1993 • 541 citations

Mapping replicational sites in the eucaryotic cell nucleus.

1989 • 520 citations

ANIMAL VIRUS DNA REPLICATION

1989 • 520 citations

Dynamic organization of DNA replication in mammalian cell nuclei: spatially and temporally defined replication of chromosome-specific alpha-satellite DNA sequences.

1992 • 478 citations

Visualization of replication factories attached to a nucleoskeleton

1993 • 472 citations

A model for initiation at origins of DNA replication

1988 • 452 citations

Structural organizations of replicon domains during DNA synthetic phase in the mammalian nucleus

1986 • 436 citations

Yeast Origin Recognition Complex Functions in Transcription Silencing and DNA Replication

1993 • 435 citations

Parameters controlling transcriptional activation during early drosophila development

1986 • 377 citations

When polymerases collide: Replication and the transcriptional organization of the E. coli chromosome

1988 • 375 citations

S Phase of the Cell Cycle

1989 • 366 citations

Cell cycle control by the nucleo-cytoplasmic ratio in early Drosophila development

1986 • 338 citations

A Three-Dimensional View of Precursor Messenger RNA Metabolism Within the Mammalian Nucleus

1993 • 335 citations

The acidic transcriptional activation domains of VP16 and p53 bind the cellular replication protein A and stimulate in vitro BPV-1 DNA replication

1993 • 329 citations

Evidence for the direct involvement of RNA in the initiation of DNA replication in Escherichia coli 15T−

1972 • 324 citations

Origin Recognition Complex (ORC) in Transcriptional Silencing and DNA Replication in S. cerevisiae

1993 • 314 citations

The events of the midblastula transition in Xenopus are regulated by changes in the cell cycle

1987 • 312 citations

EUKARYOTIC DNA REPLICATION: Anatomy of An Origin

1993 • 280 citations

A position effect on the time of replication origin activation in yeast

1992 • 263 citations

Initiation and termination of DNA replication in human rRNA genes.

1993 • 247 citations

Replication program of active and inactive multigene families in mammalian cells.

1988 • 247 citations

Transcriptional activation of initiation of replication from the E. coli chromosomal origin: An RNA-DNA hybrid near oriC

1988 • 239 citations

Cloning and expression of human TAFII250: a TBP-associated factor implicated in cell-cycle regulation

1993 • 234 citations

The transactivator proteins VP16 and GAL4 bind replication factor A

1993 • 216 citations

Chromosomal replication initiates and terminates at random sequences but at regular intervals in the ribosomal DNA of Xenopus early embryos.

1993 • 215 citations

The nucleoskeleton and the topology of replication

1991 • 205 citations

Transcription Factor OTF-1 Is Functionally Identical to the DNA Replication Factor NF-III

1988 • 194 citations

Replication occurs at discrete foci spaced throughout nuclei replicating in vitro

1989 • 192 citations

The p250 subunit of native TATA box-binding factor TFIID is the cell-cycle regulatory protein CCG1

1993 • 185 citations

Genes and genomes: Chromosome bands – flavours to savour

1993 • 182 citations

A question of time: Replication origins of eukaryotic chromosomes

1992 • 153 citations

The human CCG1 gene, essential for progression of the G1 phase, encodes a 210-kilodalton nuclear DNA-binding protein.

1991 • 131 citations

The nucleoskeleton and the topology of transcription

1989 • 110 citations

The timing of the formation and usage of replicase clusters in s-phase nuclei of human diploid fibroblasts

1991 • 101 citations

Protein-protein interactions between adenovirus DNA polymerase and nuclear factor I mediate formation of the DNA replication preinitiation complex.

1990 • 100 citations

Specific transcription factors stimulate simian virus 40 and polyomavirus origins of DNA replication.

1992 • 99 citations

Drosophila 230-kD TFIID subunit, a functional homolog of the human cell cycle gene product, negatively regulates DNA binding of the TATA box-binding subunit of TFIID.

1993 • 97 citations

Replication and transcription sites are colocalized in human cells

1994 • 96 citations

Repression of the Drosophila fushi tarazu (ftz) segmentation gene.

1991 • 92 citations

Regulation of DNA replication in vitro by the transcriptional activation domain of GAL4-VP16.

1992 • 89 citations

DNA replication occurs at discrete sites in pseudonuclei assembled from purified DNA in vitro

1991 • 76 citations

Visualization of replication sites in unfixed human cells

1993 • 66 citations

Transcription factors and the control of DNA replication

1992 • 58 citations

RPC53 Encodes a Subunit of Saccharomyces cerevisiae RNA Polymerase C (III) Whose Inactivation Leads to a Predominantly G₁ Arrest

1992 • 46 citations

Transcriptionally active minichromosomes are attached transiently in nuclei through transcription units

1993 • 40 citations

Strategies of Bacteriophage DNA Replication

1988 • 33 citations

RPC53 encodes a subunit of Saccharomyces cerevisiae RNA polymerase C (III) whose inactivation leads to a predominantly G1 arrest.

1992 • 26 citations

Inhibition of transcription blocks cell cycle progression of NIH3T3 fibroblasts specifically in G1

1993 • 24 citations

The Replication Activation Potential of Selected RNA Polymerase II Promoter Elements at the Simian Virus 40 Origin

1992 • 20 citations

Microinjection of RNA polymerase II corrects the temperature-sensitive defect of tsAF8 cells

1984 • 19 citations

The replication activation potential of selected RNA polymerase II promoter elements at the simian virus 40 origin.

1992 • 9 citations

The stimulation of the fifth force

1988 • 3 citations