The First Signs of β-Cell Autoimmunity Appear in Infancy in Genetically Susceptible Children from the General Population: The Finnish Type 1 Diabetes Prediction and Prevention Study

Measuring the Accuracy of Diagnostic Systems

1988 • 9,129 citations

ISLET-CELL ANTIBODIES IN DIABETES MELLITUS WITH AUTOIMMUNE POLYENDOCRINE DEFICIENCIES

1974 • 1,463 citations

Termination of Pregnancy on Psychiatric Grounds

1964 • 683 citations

Autoantibody appearance and risk for development of childhood diabetes in offspring of parents with type 1 diabetes: the 2-year analysis of the German BABYDIAB Study.

1999 • 633 citations

Early expression of antiinsulin autoantibodies of humans and the NOD mouse: Evidence for early determination of subsequent diabetes

2000 • 456 citations

Combined use of autoantibodies (IA-2 autoantibody, GAD autoantibody, insulin autoantibody, cytoplasmic islet cell antibodies) in type 1 diabetes: Combinatorial Islet Autoantibody Workshop.

1998 • 424 citations

A Prospective Study of the Role of Coxsackie B and Other Enterovirus Infections in the Pathogenesis of IDDM

1995 • 423 citations

A review of the recent epidemiological data on the worldwide incidence of Type 1 (insulin-dependent) diabetes mellitus

1993 • 387 citations

Combined Analysis of Autoantibodies Improves Prediction of IDDM in Islet Cell Antibody-Positive Relatives

1994 • 360 citations

Epitope specificity, cytokine production profile and diabetogenic activity of insulin‐specific T cell clones isolated from NOD mice

1995 • 359 citations

Feasibility of genetic and immunological prediction of Type I diabetes in a population-based birth cohort

2001 • 336 citations

Prediction of insulin-dependent diabetes mellitus in siblings of children with diabetes. A population-based study. The Childhood Diabetes in Finland Study Group.

1998 • 283 citations

A Comparison of Childhood and Adult Type I Diabetes Mellitus

1989 • 278 citations

A Novel Micro-assay for Insulin Autoantibodies

1997 • 238 citations

IA-2 antibodies - a sensitive marker of IDDM with clinical onset in childhood and adolescence

1998 • 182 citations

Cow's milk formula feeding induces primary immunization to insulin in infants at genetic risk for type 1 diabetes.

1999 • 181 citations

Epidemiology of childhood diabetes mellitus in Finland ? background of a nationwide study of Type 1 (insulin-dependent) diabetes mellitus

1992 • 179 citations

Genetic determination of islet cell autoimmunity in monozygotic twin, dizygotic twin, and non-twin siblings of patients with type 1 diabetes: prospective twin study

1999 • 177 citations

Record-high incidence of Type I (insulin-dependent) diabetes mellitus in Finnish children

1999 • 173 citations

Triple-label hybridization assay for type-1 diabetes-related HLA alleles.

1995 • 169 citations

Islet Cell Antibody Seroconversion in Children Is Temporally Associated with Enterovirus Infections

1997 • 165 citations

Short-term exclusive breastfeeding predisposes young children with increased genetic risk of Type I diabetes to progressive beta-cell autoimmunity

2001 • 163 citations

Autoantibodies associated with Type I diabetes mellitus persist after diagnosis in children

1998 • 157 citations

Rising Incidence of IDDM in Europe

1989 • 149 citations

Rapid HLA-DQB1 Genotyping for Four Alleles in the Assessment of Risk for IDDM in the Finnish Population

1996 • 138 citations

Correlates of Insulin Antibodies in Newly Diagnosed Children with Insulin-dependent Diabetes Before Insulin Therapy

1985 • 126 citations

Perinatal Autoimmunity in Offspring of Diabetic Parents: The German Multicenter BABY-DIAB Study: Detection of Humoral Immune Responses to Islet Antigens in Early Childhood

1996 • 118 citations

Altered immune response to insulin in newly diagnosed compared to insulin-treated diabetic patients and healthy control subjects

1997 • 78 citations

HLA-DQB1-defined genetic susceptibility, beta cell autoimmunity, and metabolic characteristics in familial and nonfamilial insulin-dependent diabetes mellitus. Childhood Diabetes in Finland (DiMe) Study Group.

1996 • 76 citations

The Fourth International Serum Exchange Workshop to standardize cytoplasmic islet cell antibodies

1991 • 72 citations

Seasonal variation in fasting plasma glucose levels in man

1982 • 65 citations

Relation Between Insulin Antibody and Complement-Fixing Islet Cell Antibody at Clinical Diagnosis of IDDM

1986 • 63 citations

Transient Antiislet Autoantibodies: Infrequent Occurrence and Lack of Association with “Genetic” Risk Factors¹

2000 • 60 citations

Costs of predicting IDDM

1998 • 53 citations

Disease-associated autoantibodies and HLA-DQB1 genotypes in children with newly diagnosed insulin-dependent diabetes mellitus (IDDM)

1999 • 48 citations

Seasonal Influence on Insulin Secretion in Man

1971 • 45 citations

Disease-associated Autoimmunity and Prevention of Insulin-dependent Diabetes Mellitus

1997 • 42 citations

Transient Antiislet Autoantibodies: Infrequent Occurrence and Lack of Association with "Genetic" Risk Factors

2000 • 40 citations

Raised temperature reduces the incidence of diabetes in the NOD mouse

1990 • 39 citations

The plasma insulin and growth hormone response to oral glucose: Diurnal and seasonal observations in the antarctic

1975 • 36 citations

Disease-Associated Antibodies in Offspring of Mothers with IDDM

1996 • 35 citations

Mouse or Man: Is GAD the cause of type I diabetes?

1994 • 14 citations