Microarrays and toxicology: The advent of toxicogenomics

Quantitative Monitoring of Gene Expression Patterns with a Complementary DNA Microarray

1995 • 9,575 citations

Whole-Genome Random Sequencing and Assembly of Haemophilus influenzae Rd

1995 • 5,571 citations

Differential Display of Eukaryotic Messenger RNA by Means of the Polymerase Chain Reaction

1992 • 5,105 citations

Exploring the Metabolic and Genetic Control of Gene Expression on a Genomic Scale

1997 • 4,531 citations

Life with 6000 Genes

1996 • 4,125 citations

Serial Analysis of Gene Expression

1995 • 3,659 citations

Resistance to HIV-1 infection in Caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene

1996 • 2,883 citations

Expression monitoring by hybridization to high-density oligonucleotide arrays

1996 • 2,796 citations

Light-Directed, Spatially Addressable Parallel Chemical Synthesis

1991 • 2,692 citations

Large-Scale Identification, Mapping, and Genotyping of Single-Nucleotide Polymorphisms in the Human Genome

1998 • 2,163 citations

Use of a cDNA microarray to analyse gene expression patterns in human cancer

1996 • 2,002 citations

Parallel human genome analysis: microarray-based expression monitoring of 1000 genes.

1996 • 1,629 citations

Accessing Genetic Information with High-Density DNA Arrays

1996 • 1,511 citations

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2018 • 1,461 citations

Light-generated oligonucleotide arrays for rapid DNA sequence analysis.

1994 • 1,353 citations

A DNA microarray system for analyzing complex DNA samples using two-color fluorescent probe hybridization.

1996 • 1,146 citations

Genome-wide expression monitoring in Saccharomyces cerevisiae

1997 • 990 citations

Discovery and analysis of inflammatory disease-related genes using cDNA microarrays

1997 • 740 citations

Genetic Risk and Carcinogen Exposure: a Common Inherited Defect of the Carcinogen-Metabolism Gene Glutathione S-Transferase M1 (GSTM1) That Increases Susceptibility to Bladder Cancer

1993 • 709 citations

Yeast microarrays for genome wide parallel genetic and gene expression analysis

1997 • 681 citations

Extensive polymorphisms observed in HIV–1 clade B protease gene using high–density oligonucleotide arrays

1996 • 545 citations

Ratio-based decisions and the quantitative analysis of cDNA microarray images

1997 • 539 citations

Detection of heterozygous mutations in BRCA1 using high density oligonucleotide arrays and two–colour fluorescence analysis

1996 • 526 citations

Gene expression profiling of alveolar rhabdomyosarcoma with cDNA microarrays.

1998 • 444 citations

DNA chips: An array of possibilities

1998 • 406 citations

Direct Allelic Variation Scanning of the Yeast Genome

1998 • 387 citations

Using oligonucleotide probe arrays to access genetic diversity

1999 • 345 citations

Data management and analysis for gene expression arrays

1998 • 300 citations

Light-directed synthesis of high-density oligonucleotide arrays using semiconductor photoresists

1996 • 248 citations

Novel gene transcripts preferentially expressed in human muscles revealed by quantitative hybridization of a high density cDNA array.

1996 • 185 citations

Cystic fibrosis mutation detection by hybridization to light-generated DNA probe arrays

1996 • 169 citations

An overview of prechronic and chronic toxicity/carcinogenicity experimental study designs and criteria used by the National Toxicology Program.

1990 • 127 citations

High-density cDNA filter analysis: a novel approach for large-scale, quantitative analysis of gene expression

1995 • 123 citations

Evolutionary sequence comparisons using high-density oligonucleotide arrays

1998 • 101 citations

Gene-Representing cDNA Clusters Defined by Hybridization of 57,419 Clones from Infant Brain Libraries with Short Oligonucleotide Probes

1996 • 84 citations

Processing of cDNA and genomic kilobase-size clones for massive screening, mapping and sequencing by hybridization.

1994 • 42 citations

Mapping Genomic Library Clones Using Oligonucleotide Arrays

1996 • 41 citations

DNA Sequence Recognition by Hybridization to Short Oligomers: Experimental Verification of the Method on theE. coliGenome

1996 • 18 citations