Modulation of plasminogen activator inhibitor-1 in vivo: A new mechanism for the anti-fibrotic effect of renin-angiotensin inhibition

Effect of Enalapril on Survival in Patients with Reduced Left Ventricular Ejection Fractions and Congestive Heart Failure

1991 • 8,296 citations

PLASMINOGEN ACTIVATOR INHIBITOR IN PLASMA: RISK FACTOR FOR RECURRENT MYOCARDIAL INFARCTION

1987 • 1,516 citations

The plasminogen activator/plasmin system.

1991 • 1,196 citations

Angiotensin II stimulates extracellular matrix protein synthesis through induction of transforming growth factor-beta expression in rat glomerular mesangial cells.

1994 • 1,063 citations

The angiotensin AT2-receptor mediates inhibition of cell proliferation in coronary endothelial cells.

1995 • 918 citations

Induction of platelet-derived growth factor A-chain and c-myc gene expressions by angiotensin II in cultured rat vascular smooth muscle cells.

1989 • 632 citations

Bleomycin-induced pulmonary fibrosis in transgenic mice that either lack or overexpress the murine plasminogen activator inhibitor-1 gene.

1996 • 559 citations

Increased type 1 plasminogen activator inhibitor gene expression in atherosclerotic human arteries.

1992 • 547 citations

Renal injury from angiotensin II-mediated hypertension.

1992 • 546 citations

Angiotensin II regulates the expression of plasminogen activator inhibitor-1 in cultured endothelial cells. A potential link between the renin-angiotensin system and thrombosis.

1995 • 539 citations

Transforming growth factor-beta 1 modulates basic fibroblast growth factor-induced proteolytic and angiogenic properties of endothelial cells in vitro.

1990 • 466 citations

Interleukin 1 and lipopolysaccharide induce an inhibitor of tissue-type plasminogen activator in vivo and in cultured endothelial cells.

1986 • 414 citations

Stimulation of plasminogen activator inhibitor in vivo by infusion of angiotensin II. Evidence of a potential interaction between the renin-angiotensin system and fibrinolytic function.

1993 • 409 citations

Induction of endothelin-1 gene by angiotensin and vasopressin in endothelial cells.

1992 • 358 citations

Tumor necrosis factor increases the production of plasminogen activator inhibitor in human endothelial cells in vitro and in rats in vivo

1988 • 300 citations

Effects of Ramipril on Plasma Fibrinolytic Balance in Patients With Acute Anterior Myocardial Infarction

1997 • 266 citations

Induction of angiotensin converting enzyme in the neointima after vascular injury. Possible role in restenosis.

1994 • 238 citations

Pathogenesis of radiation-induced myocardial fibrosis.

1973 • 234 citations

Tumor necrosis factor increases the production of plasminogen activator inhibitor in human endothelial cells in vitro and in rats in vivo

1988 • 232 citations

Enalapril reduces collagen type IV synthesis and expansion of the interstitium in the obstructed rat kidney

1994 • 214 citations

Endothelial renin-angiotensin pathway: evidence for intracellular synthesis and secretion of angiotensins.

1987 • 190 citations

Angiotensin II increases plasminogen activator inhibitor type 1 and tissue-type plasminogen activator messenger RNA in cultured rat aortic smooth muscle cells.

1994 • 177 citations

Radiation-Induced Vascular Injury and Its Relation to Late Effects in Normal Tissues

1981 • 170 citations

Vascular injury induces angiotensinogen gene expression in the media and neointima.

1993 • 140 citations

Stimulation of endothelial cell prostaglandin production by angiotensin peptides. Characterization of receptors.

1992 • 134 citations

Platelet-derived growth factor and transforming growth factor-beta regulate plasminogen activator inhibitor-1 synthesis in vascular smooth muscle cells

1991 • 133 citations

Renin expression by vascular endothelial cells in culture.

1985 • 118 citations

Capillary endothelium. Target site of renal radiation injury.

1993 • 111 citations

Cellular localization of type 1 plasminogen activator inhibitor messenger RNA and protein in murine renal tissue.

1993 • 106 citations

Role of Plasminogen-Activator Inhibitor Type 1 in the Pathogenesis and Outcome of the Hemolytic Uremic Syndrome

1992 • 96 citations

Angiotensin converting enzyme inhibitor modulates glomerular function and structure by distinct mechanisms

1994 • 95 citations

Angiotensin-Converting Enzyme Inhibition Suppresses Plasminogen Activator Inhibitor-1 Expression in the Neointima of Balloon-Injured Rat Aorta

1996 • 94 citations

Radiation pneumotoxicity in rats: Modification by inhibitors of angiotensin converting enzyme

1992 • 89 citations

Plasminogen activator inhibitor 1 in renal fibrin deposits of human nephropathies.

1990 • 80 citations

Treatment of Radiation Nephropathy with Captopril

1992 • 66 citations

Vascular Permeability and Late Radiation Fibrosis in Mouse Lung

1985 • 65 citations

The effect of Captopril on benign and malignant reactions in irradiated rat skin

1990 • 58 citations

Angiotensin Converting Enzyme Inhibitors as Oxygen Free Radical Scavengers

1993 • 58 citations

Induction of plasminogen activator inhibitor type 1 in murine lupus-like glomerulonephritis

1995 • 55 citations

Expression of type 1 plasminogen activator inhibitor in renal tissue in murine lupus nephritis

1995 • 50 citations

Inhibition of vascular permeability changes in rats by captopril.

1982 • 49 citations

Autocrine angiotensin system regulation of bovine aortic endothelial cell migration and plasminogen activator involves modulation of proto-oncogene pp60c-src expression.

1992 • 46 citations

Expression of plasminogen activator-inhibitor-1 (PAI-1) during cellular remodeling in proliferative glomerulonephritis in the rat.

1995 • 35 citations

LPS induces major changes in the extracellular proteolytic balance in the murine kidney

1994 • 28 citations

Effect of angiotensin II on the expression of plasminogen activator inhibitor -1 in rat mesangial cells

1994 • 5 citations

Mechanisms of hypertension in renal radiation.

1990 • 2 citations