Millisecond-timescale, genetically targeted optical control of neural activity

Synaptic Modifications in Cultured Hippocampal Neurons: Dependence on Spike Timing, Synaptic Strength, and Postsynaptic Cell Type

1998 • 4,476 citations

A Third-Generation Lentivirus Vector with a Conditional Packaging System

1998 • 3,175 citations

Channelrhodopsin-2, a directly light-gated cation-selective membrane channel

2003 • 2,582 citations

Reliability of Spike Timing in Neocortical Neurons

1995 • 1,957 citations

Selective gating of visual signals by microstimulation of frontal cortex

2003 • 1,152 citations

Channelrhodopsin-1: A Light-Gated Proton Channel in Green Algae

2002 • 1,103 citations

Complex Movements Evoked by Microstimulation of Precentral Cortex

2002 • 904 citations

Cortical microstimulation influences perceptual judgements of motion direction

1990 • 884 citations

Synfire Chains and Cortical Songs: Temporal Modules of Cortical Activity

2004 • 845 citations

Light-activated ion channels for remote control of neuronal firing

2004 • 688 citations

Excitation-Neurogenesis Coupling in Adult Neural Stem/Progenitor Cells

2004 • 656 citations

Excitatory cortical neurons form fine-scale functional networks

2005 • 633 citations

Remote Control of Behavior through Genetically Targeted Photostimulation of Neurons

2005 • 562 citations

Two rhodopsins mediate phototaxis to low- and high-intensity light in Chlamydomonas reinhardtii

2002 • 529 citations

Selective Photostimulation of Genetically ChARGed Neurons

2002 • 496 citations

ELECTROPHYSIOLOGY OF HIPPOCAMPAL NEURONS: I. SEQUENTIAL INVASION AND SYNAPTIC ORGANIZATION

1961 • 483 citations

Routing of spike series by dynamic circuits in the hippocampus

2004 • 435 citations

Circuit Analysis of Experience-Dependent Plasticity in the Developing Rat Barrel Cortex

2003 • 326 citations

Laminar sources of synaptic input to cortical inhibitory interneurons and pyramidal neurons

2000 • 320 citations

Electrophysiology of Hippocampal Neurons

1987 • 292 citations

Rhodopsin-regulated calcium currents in Chlamydomonas

1991 • 265 citations

Photochemical gating of heterologous ion channels: Remote control over genetically designated populations of neurons

2003 • 244 citations

Layer-Specific Intracolumnar and Transcolumnar Functional Connectivity of Layer V Pyramidal Cells in Rat Barrel Cortex

2001 • 238 citations

Microstimulation of visual cortex affects the speed of perceptual decisions

2003 • 235 citations

Critical Dependence of cAMP Response Element-Binding Protein Phosphorylation on L-Type Calcium Channels Supports a Selective Response to EPSPs in Preference to Action Potentials

2000 • 195 citations

Stereotyped Position of Local Synaptic Targets in Neocortex

2001 • 182 citations

Scanning laser photostimulation: a new approach for analyzing brain circuits

1994 • 162 citations

Archaeal-type rhodopsins in Chlamydomonas: model structure and intracellular localization

2003 • 161 citations

Multiphoton stimulation of neurons

2002 • 160 citations

Rearrangements of Synaptic Connections in Visual Cortex Revealed by Laser Photostimulation

1994 • 140 citations

Local Excitatory Circuits in the Intermediate Gray Layer of the Superior Colliculus

1999 • 78 citations