Critical Dependence of cAMP Response Element-Binding Protein Phosphorylation on L-Type Calcium Channels Supports a Selective Response to EPSPs in Preference to Action Potentials

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

Down-Regulation of Na⁺/K⁺ATPase Activity by Human Parvovirus B19 Capsid Protein VP1

2013 • 8,607 citations

Ionic channels of excitable membranes

1985 • 7,199 citations

Regulation of the Voltage Gated K<sup>+</sup> Channel K<sub>v1.3</sub> by Recombinant Human Klotho Protein

2014 • 5,592 citations

Synaptic Modifications in Cultured Hippocampal Neurons: Dependence on Spike Timing, Synaptic Strength, and Postsynaptic Cell Type

1998 • 4,476 citations

Ca2+ Influx Regulates BDNF Transcription by a CREB Family Transcription Factor-Dependent Mechanism

1998 • 1,504 citations

CREB: a Ca ²⁺ -Regulated Transcription Factor Phosphorylated by Calmodulin-Dependent Kinases

1991 • 1,476 citations

CREB Phosphorylation and Dephosphorylation: A Ca2+- and Stimulus Duration–Dependent Switch for Hippocampal Gene Expression

1996 • 1,109 citations

Cross Talk between ERK and PKA Is Required for Ca2+ Stimulation of CREB-Dependent Transcription and ERK Nuclear Translocation

1998 • 885 citations

Pharmacological dissection of multiple types of Ca2+ channel currents in rat cerebellar granule neurons

1995 • 819 citations

Regulation of CREB Phosphorylation in the Suprachiasmatic Nucleus by Light and a Circadian Clock

1993 • 817 citations

Signaling from Synapse to Nucleus: Postsynaptic CREB Phosphorylation during Multiple Forms of Hippocampal Synaptic Plasticity

1996 • 701 citations

Identification of a Signaling Pathway Involved in Calcium Regulation of BDNF Expression

1998 • 687 citations

Translocation of calmodulin to the nucleus supports CREB phosphorylation in hippocampal neurons

1998 • 640 citations

Estradiol reduces calcium currents in rat neostriatal neurons via a membrane receptor

1996 • 638 citations

L-type calcium channels and GSK-3 regulate the activity of NF-ATc4 in hippocampal neurons

1999 • 521 citations

Neurotrophin Regulation of Cortical Dendritic Growth Requires Activity

1996 • 503 citations

Synaptic Activation of Voltage-Gated Channels in the Dendrites of Hippocampal Pyramidal Neurons

1995 • 449 citations

L-type voltage-sensitive calcium channels mediate synaptic activation of immediate early genes

1991 • 429 citations

Glutamate-induced long-term potentiation of the frequency of miniature synaptic currents in cultured hippocampal neurons

1992 • 421 citations

Calcium regulation of gene expression in neuronal cells

1994 • 327 citations

Novel form of long-term potentiation produced by a K+channel blocker in the hippocampus

1991 • 321 citations

Action Potential-Dependent Regulation of Gene Expression: Temporal Specificity in Ca²⁺, cAMP-Responsive Element Binding Proteins, and Mitogen-Activated Protein Kinase Signaling

1997 • 304 citations

Reversal of Age-Related Alterations in Synaptic Plasticity by Blockade of L-Type Ca²⁺Channels

1998 • 275 citations

Calcium concentration dynamics produced by synaptic activation of CA1 hippocampal pyramidal cells

1992 • 239 citations

Different Ca2+ channels in soma and dendrites of hippocampal pyramidal neurons mediate spike-induced Ca2+ influx

1995 • 222 citations

Aging Differentially Alters Forms of Long-Term Potentiation in Rat Hippocampal Area CA1

1998 • 218 citations

N-methyl-D-aspartate receptor-induced proteolytic conversion of postsynaptic class C L-type calcium channels in hippocampal neurons.

1996 • 200 citations

Changes in action potential duration alter reliance of excitatory synaptic transmission on multiple types of Ca2+ channels in rat hippocampus

1996 • 199 citations

Cellular and molecular characterization of Ca2+ currents in acutely isolated, adult rat neostriatal neurons

1994 • 196 citations

Multiple Channel Types Contribute to the Low-Voltage-Activated Calcium Current in Hippocampal CA3 Pyramidal Neurons

1996 • 195 citations

Spatiotemporal Dynamics of CREB Phosphorylation: Transient versus Sustained Phosphorylation in the Developing Striatum

1996 • 195 citations

Dihydropyridine‐sensitive and omega‐conotoxin‐sensitive calcium channels in a mammalian neuroblastoma‐glioma cell line.

1992 • 181 citations

Induction of c-fos expression in hypothalamic magnocellular neurons requires synaptic activation and not simply increased spike activity

1994 • 174 citations

Calcineurin controls inositol 1,4,5-trisphosphate type 1 receptor expression in neurons

1999 • 171 citations

L-Type Ca²⁺Channels Are Essential for Glutamate-Mediated CREB Phosphorylation andc-fosGene Expression in Striatal Neurons

1999 • 168 citations

L-Type Calcium Channels Are Required for One Form of Hippocampal Mossy Fiber LTP

1998 • 163 citations

L-type voltage-sensitive calcium channel activation stimulates gene expression by a serum response factor-dependent pathway.

1994 • 148 citations

L-type Voltage-sensitive Ca2+ Channel Activation Regulates c-fos Transcription at Multiple Levels

1995 • 146 citations

Mechanisms controlling gene expression by nuclear calcium signals

1998 • 134 citations

Ca2+-regulated Dynamic Compartmentalization of Calmodulin in Living Smooth Muscle Cells

1995 • 106 citations

Distinct LTP induction mechanisms: contribution of NMDA receptors and voltage-dependent calcium channels

1995 • 103 citations

Hormone-induced secretory and nuclear translocation of calmodulin: Oscillations of calmodulin concentration with the nucleus as an integrator

1999 • 86 citations

A Role for L-Type Calcium Channels in Developmental Regulation of Transmitter Phenotype in Primary Sensory Neurons

1998 • 81 citations

Subtype-specific involvement of metabotropic glutamate receptors in two forms of long-term potentiation in the dentate gyrus of freely moving rats

1998 • 76 citations

Facilitated nuclear transport of calmodulin in tissue culture cells.

1994 • 66 citations

Mechanism of Ca ²⁺ -dependent nuclear accumulation of calmodulin

1999 • 56 citations

Some principles emerging from the study of short- and long-term memory

1986 • 52 citations

Tyrosine Hydroxylase Expression in Primary Cultures of Olfactory Bulb: Role of L-Type Calcium Channels

1998 • 50 citations

Voltage-dependent facilitation of calcium channels in rat neostriatal neurons

1996 • 48 citations

Effects of synaptic and antidromic stimulation on tyrosine hydroxylase activity in the rat superior cervical ganglion.

1980 • 47 citations

Functional characterization of the effect of nimodipine on the calcium current in rat cerebellar granule cells

1995 • 47 citations

Light‐Induced CREB Phosphorylation and Gene Expression in Rat Retinal Cells

1995 • 43 citations

Region-dependent dynamics of cAMP response element-binding protein phosphorylation in the basal ganglia

1998 • 42 citations

L-type voltage-sensitive calcium channel antagonists block heterosynaptic long-term depression in the dentate gyrus of anaesthetized rats

1994 • 41 citations

Activation of Nuclear Calcium Dynamics by Synaptic Stimulation in Cultured Cortical Neurons

1999 • 37 citations

Stimulation of L-type Ca2+ channel in growth cones activates two independent signaling pathways

1998 • 37 citations

Long-term potentiation in the hippocampal CA1 region in the presence ofN-methyl-d-aspartate receptor antagonists

1995 • 22 citations

LTP in CA1 of the adult rat hippocampus and voltage-activated calcium channels

1998 • 16 citations

Nimodipine Suppresses Preferential Reinnervation of Mouse Soleus Muscles by Slow α-Motoneurons

1998 • 9 citations