Remote Control of Behavior through Genetically Targeted Photostimulation of Neurons

The capsaicin receptor: a heat-activated ion channel in the pain pathway

1997 • 8,634 citations

Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase.

1990 • 3,250 citations

The Cloned Capsaicin Receptor Integrates Multiple Pain-Producing Stimuli

1998 • 3,026 citations

Getting Formal with Dopamine and Reward

2002 • 2,558 citations

Cocaine Receptors on Dopamine Transporters Are Related to Self-Administration of Cocaine

1987 • 2,189 citations

A Drosophila model of Parkinson's disease

2000 • 2,062 citations

Correlates of Sleep and Waking in Drosophila melanogaster

2000 • 1,244 citations

A new class of ligand-gated ion channel defined by P2X receptor for extracellular ATP

1994 • 1,039 citations

Rest in Drosophila Is a Sleep-like State

2000 • 1,007 citations

New structural motif for ligand-gated ion channels defined by an ionotropic ATP receptor

1994 • 924 citations

Targeted expression of tetanus toxin light chain in Drosophila specifically eliminates synaptic transmission and causes behavioral defects

1995 • 921 citations

Dopaminergic Modulation of Neuronal Excitability in the Striatum and Nucleus Accumbens

2000 • 916 citations

Conditional modification of behavior inDrosophilaby targeted expression of a temperature‐sensitiveshibireallele in defined neurons

2001 • 837 citations

The command neuron concept

1978 • 786 citations

Dopamine and octopamine differentiate between aversive and appetitive olfactory memories in Drosophila.

2003 • 761 citations

Rapid photolytic release of adenosine 5'-triphosphate from a protected analog: utilization by the sodium:potassium pump of human red blood cell ghosts

1978 • 743 citations

Dopamine and Octopamine Differentiate between Aversive and Appetitive Olfactory Memories inDrosophila

2003 • 717 citations

Ectopic and increased expression of fasciclin II alters motoneuron growth cone guidance

1994 • 690 citations

Light-activated ion channels for remote control of neuronal firing

2004 • 688 citations

Isolation of a putative phospholipase c gene of drosophila, norpA, and its role in phototransduction

1988 • 665 citations

Targeted gene expression in Drosophila dopaminergic cells using regulatory sequences from tyrosine hydroxylase

2003 • 521 citations

Selective Photostimulation of Genetically ChARGed Neurons

2002 • 496 citations

The neurobiology of an insect brain

1997 • 496 citations

Ion Channels and Synaptic Organization

2000 • 475 citations

Combinatorial Expression of TRPV Channel Proteins Defines Their Sensory Functions and Subcellular Localization in C. elegans Neurons

2002 • 455 citations

Neural mechanisms of startle behavior

1987 • 420 citations

Neural Mechanisms of Startle Behavior

1984 • 397 citations

Photostimulation using caged glutamate reveals functional circuitry in living brain slices.

1993 • 396 citations

Properties and Uses of Photoreactive Caged Compounds

1989 • 389 citations

Fighting fruit flies: A model system for the study of aggression

2002 • 383 citations

Interneurons commanding swimmeret movements in the crayfish, Procambarus clarki (girard)

1964 • 325 citations

Dopamine modulates acute responses to cocaine, nicotine and ethanol in Drosophila

2000 • 315 citations

Genetic Dissection of the Drosophila Nervous System by Means of Mosaics

1970 • 297 citations

Context generalization in Drosophila visual learning requires the mushroom bodies

1999 • 290 citations

Motor outputs of giant nerve fiber in Drosophila.

1980 • 275 citations

Inducible Genetic Suppression of Neuronal Excitability

1999 • 269 citations

Oscillatory Neural Networks

1985 • 262 citations

Photochemical gating of heterologous ion channels: Remote control over genetically designated populations of neurons

2003 • 244 citations

Neuromodulation : the biochemical control of neuronal excitability

1987 • 237 citations

Laser Stimulation of Nerve Cells in Aplysia

1971 • 235 citations

GAL4 enhancer traps expressed in the embryo, larval brain, imaginal discs, and ovary of drosophila

1997 • 232 citations

Single-Cell Analysis of Drosophila Larval Neuromuscular Synapses

2001 • 228 citations

Conserved and sexually dimorphic behavioral responses to biogenic amines in decapitated Drosophila

1997 • 218 citations

Mutants of the Visual Pathway of Drosophila melanogaster

1970 • 190 citations

Stereotypic behavioral responses to free-base cocaine and the development of behavioral sensitization in Drosophila

1998 • 187 citations

Mutations altering synaptic connectivity between identified neurons in Drosophila

1984 • 186 citations

Aloysii Galvani De viribus electricitatis in motu musculari commentarius

1791 • 185 citations

Catecholamine‐containing neurons in Drosophila melanogaster: Distribution and development

1988 • 176 citations

Mutations in the dopa decarboxylase gene affect learning in Drosophila.

1984 • 161 citations

Blood Barriers of the Insect

2000 • 153 citations

A Genetic Method for Selective and Quickly Reversible Silencing of Mammalian Neurons

2002 • 150 citations

Localization of choline acetyltransferase-expressing neurons inDrosophila nervous system

1999 • 145 citations

Selective Electrical Silencing of Mammalian NeuronsIn Vitroby the Use of Invertebrate Ligand-Gated Chloride Channels

2002 • 132 citations

Targeted Expression of TruncatedGluedDisrupts Giant Fiber Synapse Formation inDrosophila

1999 • 104 citations

Dynamic visualization of nervous system in live Drosophila

1999 • 103 citations

A simple chemosensory response in Drosophila and the isolation of acj mutants in which it is affected.

1989 • 100 citations

Learning and Courtship in Drosophila: Two Stories with Mutants

1984 • 90 citations

Motor program selection in simple model systems

2001 • 89 citations

Neuromodulation: The biochemical control of neuronal excitability

1987 • 84 citations

The morphology of the cervical giant fiber neuron ofDrosophila

1981 • 76 citations

Excitatory and Inhibitory Switches for Courtship in the Brain of Drosophila melanogaster

2004 • 76 citations

The Drosophila Giant Fiber System

1984 • 75 citations

Turning behavior induced by electrical stimulation of the nigro-neostriatal system of the rat

1975 • 67 citations

Genes Expressed in the Adult Brain ofDrosophilaand Effects of Their Mutations on Behavior: A Survey of Transmitter- and Second Messenger-Related Genes

1991 • 67 citations

The Neurobiology of an Insect Brain

1997 • 64 citations

Ectopic expression of sex-peptide in a variety of tissues in Drosophila females using the P[GAL4] enhancer-trap system

1997 • 63 citations

A mutation in Drosophila alters normal connectivity between two identified neurones

1982 • 63 citations

Genetic methods for illuminating the function of neural circuits

2004 • 59 citations

Identification of Presynaptic Neurons by Laser Photostimulation

1983 • 59 citations

Flight initiations in Drosophila melanogaster are mediated by several distinct motor patterns

1995 • 47 citations

Synaptogenesis in the Giant-Fibre System of Drosophila: interaction of the Giant Fibre and its major motorneuronal target

2000 • 46 citations

Genetic schemes and schemata in neurophysiology

2001 • 28 citations

Controlling the Motor Neuron

1999 • 24 citations