Differential effects of phorbol ester on the in vitro invasiveness of malignant and non‐malignant human fibroblast cells

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

A rapid in vitro assay for quantitating the invasive potential of tumor cells.

1987 • 1,787 citations

Basement membrane complexes with biological activity

1986 • 1,489 citations

Isolation and characterization of type IV procollagen, laminin, and heparan sulfate proteoglycan from the EHS sarcoma

1982 • 1,225 citations

H-ras oncogene-transformed human bronchial epithelial cells (TBE-1) secrete a single metalloprotease capable of degrading basement membrane collagen.

1988 • 1,050 citations

BIOCHEMICAL INTERACTIONS OF TUMOR CELLS WITH THE BASEMENT MEMBRANE

1986 • 693 citations

Effects of inhibitors of plasminogen activator, serine proteinases, and collagenase IV on the invasion of basement membranes by metastatic cells

1988 • 352 citations

Role of laminin in the attachment and metastasis of murine tumor cells.

1982 • 334 citations

Phosphoinositides and receptor mechanisms

1987 • 320 citations

Novel source of 1,2-diacylglycerol elevated in cells transformed by Ha-ras oncogene

1987 • 303 citations

Biosynthesis of tissue inhibitor of metalloproteinases by human fibroblasts in culture. Stimulation by 12-O-tetradecanoylphorbol 13-acetate and interleukin 1 in parallel with collagenase.

1985 • 220 citations

Laminin increases the release of type IV collagenase from malignant cells.

1986 • 188 citations

Invasion of reconstituted basement membrane matrix by metastatic human tumor cells.

1986 • 160 citations

Collagenolytic mechanisms in tumor cell invasion

1984 • 146 citations

Involvement of functional protein kinase C in the mitogenic response to the H-ras oncogene product.

1987 • 131 citations

Mechanism of activation of an N-ras gene in the human fibrosarcoma cell line HT1080.

1984 • 124 citations

Activated N-ras controls the transformed phenotype of HT1080 human fibrosarcoma cells

1987 • 109 citations

Tumor promoter-induced membrane-bound protein kinase C regulates hematogenous metastasis.

1988 • 107 citations

Tumor-promoting phorbol esters and cell proliferation stimulate secretion of basement membrane (type IV) collagen-degrading metalloproteinase by human fibroblasts.

1985 • 96 citations

Partial down-regulation of protein kinase C in C3H 10T 1/2 mouse fibroblasts transfected with the human Ha-ras oncogene.

1988 • 63 citations

Effects of 12-O-tetradecanoylphorbol-13-acetate on adhesiveness and lung-colonizing ability of Lewis lung carcinoma cells.

1986 • 63 citations

Induction of plasminogen activator in cultured cells by macrocyclic plant diterpene esters and other agents related to tumor promotion.

1978 • 61 citations

Molecular cloning of gene sequences regulated by tumor promoters and mitogens through protein kinase C.

1987 • 55 citations

Expression of the Aplysia Californica Rho Gene in Escherichia Coli: Purification and Characterization of Its Encoded p21 Product

1987 • 32 citations

The role of cell adhesion and migration in the in vitro invasiveness of mouse adrenal carcinoma cells.

1990 • 23 citations

Influence of Plasma Fibronectin on Collagen Cleavage by Collagenase

1983 • 19 citations

Inhibitors of Collagenase IV and Cell Adhesion Reduce the Invasive Activity of Malignant Tumour Cells

2007 • 11 citations

The role of animal models in the study of experimental metastasis

1982 • 9 citations