Mouse MutS-like protein Msh5 is required for proper chromosome synapsis in male and female meiosis

PCR protocols — A guide to methods and applications

1990 • 10,078 citations

Histological and Histopathological Evaluation of the Testis

1993 • 2,232 citations

MECHANISMS AND BIOLOGICAL EFFECTS OF MISMATCH REPAIR

1991 • 876 citations

Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma.

1996 • 851 citations

Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over

1996 • 800 citations

Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer

1995 • 785 citations

A drying-down technique for the spreading of mammalian meiocytes from the male and female germline.

1997 • 713 citations

Meiotic Prophase Arrest with Failure of Chromosome Synapsis in Mice Deficient for Dmc1 , a Germline-Specific RecA Homolog

1998 • 624 citations

Isolation of an hMSH2-p160 Heterodimer That Restores DNA Mismatch Repair to Tumor Cells

1995 • 599 citations

Biochemistry and genetics of eukaryotic mismatch repair.

1996 • 598 citations

Redundancy of Saccharomyces cerevisiae MSH3 and MSH6 in MSH2-dependent mismatch repair.

1996 • 576 citations

The Mouse RecA-like Gene Dmc1 Is Required for Homologous Chromosome Synapsis during Meiosis

1998 • 568 citations

Meiotic Pachytene Arrest in MLH1-Deficient Mice

1996 • 549 citations

Male mice defective in the DNA mismatch repair gene PMS2 exhibit abnormal chromosome synapsis in meiosis

1995 • 536 citations

GTBP, a 160-Kilodalton Protein Essential for Mismatch-binding Activity in Human Cells

1995 • 528 citations

Highly efficient gene targeting in embryonic stem cells through homologous recombination with isogenic DNA constructs.

1992 • 450 citations

Centromere and telomere movements during early meiotic prophase of mouse and man are associated with the onset of chromosome pairing.

1996 • 431 citations

Isolation of MutSβ from Human Cells and Comparison of the Mismatch Repair Specificities of MutSβ and MutSα

1998 • 405 citations

Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologs.

1995 • 403 citations

A coiled-coil related protein specific for synapsed regions of meiotic prophase chromosomes.

1992 • 397 citations

MSH5, a novel MutS homolog, facilitates meiotic reciprocal recombination between homologs in Saccharomyces cerevisiae but not mismatch repair.

1995 • 391 citations

Synaptonemal complex proteins: occurrence, epitope mapping and chromosome disjunction

1994 • 386 citations

Mutation of a meiosis-specific MutS homolog decreases crossing over but not mismatch correction

1994 • 371 citations

Mutation in the Mismatch Repair Gene Msh6 Causes Cancer Susceptibility

1997 • 359 citations

Tumour susceptibility and spontaneous mutation in mice deficient in Mlh1, Pms1 and Pms2 DMA mismatch repair

1998 • 351 citations

Stem cells in the testis

1998 • 318 citations

The meiotic checkpoint monitoring sypapsis eliminates spermatocytes via p53-independent apoptosis

1998 • 259 citations

Mlh1 is unique among mismatch repair proteins in its ability to promote crossing-over during meiosis.

1997 • 243 citations

Roles for two RecA homologs in promoting meiotic chromosome synapsis.

1995 • 202 citations

Synaptonemal complexes: structure and function

1996 • 199 citations

Requirement of the Yeast MSH3 and MSH6 Genes for MSH2-dependent Genomic Stability

1996 • 187 citations

Spontaneous intestinal carcinomas and skin neoplasms in Msh2-deficient mice.

1996 • 165 citations

Mouse models for hereditary nonpolyposis colorectal cancer.

1998 • 162 citations

Functional Overlap in Mismatch Repair by Human MSH3 and MSH6

1998 • 152 citations

Analysis of chromosome behavior in intact mammalian oocytes: monitoring the segregation of a univalent chromosome during female meiosis

1995 • 146 citations

Sperm-count, egg-fertilization and dominant lethality after X-irradiation of mice

1974 • 143 citations

Morphological and temporal sequence of meiotic prophase development at puberty in the male mouse

1984 • 135 citations

Conserved Properties between Functionally Distinct MutS Homologs in Yeast

1997 • 126 citations

Update on the differential diagnosis, surveillance and management of hereditary non-polyposis colorectal cancer

1995 • 50 citations

Tissue distribution of two major components of synaptonemal complexes of the rat

1991 • 48 citations

Mechanisms And Biological Effects Of Mismatch Repair

1991 • 45 citations

A sequential analysis of the development of the synaptonemal complex in spermatocytes of the mouse by electron microscopy using hydroxyurea and agar filtration

1983 • 35 citations

A male-sterile insertion in the mouse

1983 • 24 citations

Sperm-count, egg-fertilization and dominant lethality after x-irradiation of mice

1974 • 11 citations