Stromal Cell-Derived Factor-1-CXC Chemokine Receptor 4 Interactions Play a Central Role in CD4+ T Cell Accumulation in Rheumatoid Arthritis Synovium

The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis

1988 • 19,632 citations

Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm

1994 • 7,068 citations

Adhesion receptors of the immune system

1990 • 6,585 citations

Lymphocyte Homing and Homeostasis

1996 • 2,934 citations

Leukocyte-endothelial cell recognition: Three (or more) steps to specificity and diversity

1991 • 2,806 citations

Chemokines and leukocyte traffic

1998 • 2,755 citations

Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development

1998 • 2,496 citations

Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1

1996 • 2,374 citations

Human Chemokines: An Update

1997 • 2,235 citations

Flexible Programs of Chemokine Receptor Expression on Human Polarized T Helper 1 and 2 Lymphocytes

1998 • 1,574 citations

The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract

1998 • 1,535 citations

A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1)

1996 • 1,482 citations

The Chemokine SDF-1 Is a Chemoattractant for Human CD34+ Hematopoietic Progenitor Cells and Provides a New Mechanism to Explain the Mobilization of CD34+ Progenitors to Peripheral Blood

1997 • 1,414 citations

The chemokine receptors CXCR3 and CCR5 mark subsets of T cells associated with certain inflammatory reactions.

1998 • 1,382 citations

Chemokine receptor specific for IP10 and mig: structure, function, and expression in activated T-lymphocytes.

1996 • 1,196 citations

The HIV coreceptors CXCR4 and CCR5 are differentially expressed and regulated on human T lymphocytes

1997 • 1,124 citations

Structure and Functional Expression of a Human Interleukin-8 Receptor

1991 • 1,088 citations

Chemokines and the Arrest of Lymphocytes Rolling Under Flow Conditions

1998 • 1,013 citations

Chemokines and chemokine receptors in T-cell priming and Th1/Th2-mediated responses

1998 • 918 citations

Cloning of Complementary DNA Encoding a Functional Human Interleukin-8 Receptor

1991 • 878 citations

Molecular cloning and structure of a pre-B-cell growth-stimulating factor.

1994 • 818 citations

Molecular cloning, functional expression, and signaling characteristics of a C-C chemokine receptor

1993 • 771 citations

Signal Sequence Trap: a Cloning Strategy for Secreted Proteins and Type I Membrane Proteins

1993 • 722 citations

Molecular cloning and functional expression of two monocyte chemoattractant protein 1 receptors reveals alternative splicing of the carboxyl-terminal tails.

1994 • 711 citations

Molecular cloning and characterization of a human eotaxin receptor expressed selectively on eosinophils.

1996 • 626 citations

Cloning, expression, and characterization of the human eosinophil eotaxin receptor.

1996 • 561 citations

Interleukin-15 mediates T cell-dependent regulation of tumor necrosis factor-α production in rheumatoid arthritis

1997 • 513 citations

The role of interleukin–15 in T–cell migration and activation in rheumatoid arthritis

1996 • 492 citations

Cloning of a human seven-transmembrane domain receptor, LESTR, that is highly expressed in leukocytes.

1994 • 460 citations

Molecular Cloning and Functional Characterization of a Novel Human CC Chemokine Receptor (CCR5) for RANTES, MIP-1β, and MIP-1α

1996 • 454 citations

Apoptosis in rheumatoid arthritis synovium.

1995 • 378 citations

Chemokine expression in murine experimental allergic encephalomyelitis

1995 • 363 citations

The chemokine SDF‐1, stromal cell‐derived factor 1, attracts early stage B cell precursors via the chemokine receptor CXCR4

1997 • 339 citations

Epstein-Barr virus-induced genes: first lymphocyte-specific G protein-coupled peptide receptors

1993 • 323 citations

Expression of the cytokine RANTES in human rheumatoid synovial fibroblasts. Differential regulation of RANTES and interleukin-8 genes by inflammatory cytokines.

1993 • 296 citations

[361 Construction of cDNA libraries from single cells

1993 • 271 citations

Molecular Cloning and Functional Expression of a Novel CC Chemokine Receptor cDNA from a Human Basophilic Cell Line

1995 • 267 citations

Intracellular and Surface Expression of the HIV-1 Coreceptor CXCR4/Fusin on Various Leukocyte Subsets: Rapid Internalization and Recycling Upon Activation

1998 • 266 citations

Production of interleukin-7 and interleukin-15 by fibroblast-like synoviocytes from patients with rheumatoid arthritis

1999 • 249 citations

Cloning and Functional Expression of a Human Eosinophil CC Chemokine Receptor

1995 • 246 citations

Interleukin 15 is produced by endothelial cells and increases the transendothelial migration of T cells In vitro and in the SCID mouse-human rheumatoid arthritis model In vivo.

1998 • 234 citations

Cloning and Characterization of a Novel Promiscuous Human β-Chemokine Receptor D6

1997 • 229 citations

Cutting Edge: Stromal Cell-Derived Factor-1 Is a Costimulator for CD4+ T Cell Activation

2000 • 199 citations

Molecular Cloning of the cDNA and Chromosomal Localization of the Gene for a Putative Seven-Transmembrane Segment (7-TMS) Receptor Isolated from Human Spleen

1993 • 192 citations

IL-4 induces functional cell-surface expression of CXCR4 on human T cells.

1998 • 169 citations

Functional CD40 ligand is expressed by T cells in rheumatoid arthritis.

1997 • 166 citations

Expression of the chemokine superfamily in rheumatoid arthritis

1994 • 164 citations

Molecular cloning of cDNAs encoding a LD78 receptor and putative leukocyte chemotactic peptide receptors

1993 • 154 citations

CC chemokine receptor 5 polymorphism in rheumatoid arthritis.

1998 • 152 citations

Differentiation‐specific expression of a novel G protein‐coupled receptor from Burkitt's lymphoma

1992 • 147 citations

Flow cytometric single-cell analysis of cytokine production by CD4+ T cells in synovial tissue and peripheral blood from patients with rheumatoid arthritis

1998 • 146 citations

Selective accumulation of CCR5+ T lymphocytes into inflamed joints of rheumatoid arthritis

1999 • 143 citations

Predominance of mononuclear cells expressing the chemokine receptor CCR5 in synovial effusions of patients with different forms of arthritis

1999 • 142 citations

The Role of CD8+ CD40L+ T Cells in the Formation of Germinal Centers in Rheumatoid Synovitis

1998 • 142 citations

Cutting Edge: IL-4 Induces Functional Cell-Surface Expression of CXCR4 on Human T Cells

1998 • 139 citations

Enrichment of differentiated CD45RB^dim, CD27 – memory T cells in the peripheral blood, synovial fluid, and synovial tissue of patients with rheumatoid arthritis

1996 • 120 citations

Molecular Cloning, Characterization, and Localization of the Human Homolog to the Reported Bovine NPY Y3 Receptor: Lack of NPY Binding and Activation

1993 • 110 citations

TCR Activation Inhibits Chemotaxis Toward Stromal Cell-Derived Factor-1: Evidence for Reciprocal Regulation Between CXCR4 and the TCR

1999 • 105 citations

Cloning, Expression, and Chromosomal Mapping of a Novel Human CC-Chemokine Receptor (CCR10) That Displays High-Affinity Binding for MCP-1 and MCP-3

1997 • 101 citations

IL-4 and a glucocorticoid up-regulate CXCR4 expression on human CD4+ T lymphocytes and enhance HIV-1 replication

1998 • 97 citations

Abnormalities in CD4+ T-lymphocyte subsets in inflammatory rheumatic diseases

1988 • 85 citations

Use of a differential subtraction method to identify genes that characterize the phenotype of cultured rheumatoid arthritis synoviocytes

1998 • 74 citations

Molecular cloning of TER1, a chemokine receptor-like gene expressed by lymphoid tissues.

1996 • 63 citations

The functional CD40 antigen of fibroblasts may contribute to the proliferation of rheumatoid synovium

1996 • 58 citations

Molecular cloning of TER1, a chemokine receptor-like gene expressed by lymphoid tissues.

1996 • 56 citations

Cloning of STRL22, a New Human Gene Encoding a G-Protein-Coupled Receptor Related to Chemokine Receptors and Located on Chromosome 6q27

1997 • 54 citations

The ?32 deletion of CCR5 receptor in rheumatoid arthritis

1998 • 48 citations

Molecular Cloning of TPAR1, a Gene Whose Expression Is Repressed by the Tumor Promoter 12-O-Tetradecanoylphorbol 13-Acetate (TPA)

1994 • 40 citations

Expression and function of CD40 in rheumatoid arthritis synovium.

1998 • 30 citations

The use of reverse transcription polymerase chain reaction to analyse large numbers of mRNA species from a single cell

1996 • 20 citations