Structural Transitions at Microtubule Ends Correlate with Their Dynamic Properties in Xenopus Egg Extracts

Dynamic instability of microtubule growth

1984 • 3,187 citations

Dynamic instability of individual microtubules analyzed by video light microscopy: rate constants and transition frequencies.

1988 • 985 citations

Chapter 30 Cell Cycle Extracts

1991 • 953 citations

[39] Preparation of modified tubulins

1991 • 724 citations

Identification of a Protein That Interacts with Tubulin Dimers and Increases the Catastrophe Rate of Microtubules

1996 • 651 citations

Visualization of the dynamic instability of individual microtubules by dark-field microscopy

1986 • 547 citations

Microtubule dynamics and microtubule caps: a time-resolved cryo-electron microscopy study.

1991 • 544 citations

Real-time visualization of cell cycle-dependent changes in microtubule dynamics in cytoplasmic extracts

1990 • 444 citations

Structure of growing microtubule ends: two-dimensional sheets close into tubes at variable rates.

1995 • 429 citations

Role of GTP hydrolysis in microtubule dynamics: information from a slowly hydrolyzable analogue, GMPCPP.

1992 • 376 citations

Direct observation of microtubule dynamics in living cells

1988 • 318 citations

Cell cycle extracts.

1991 • 304 citations

Morphogenetic Properties of Microtubules and Mitotic Spindle Assembly

1996 • 292 citations

Structural and chemical characterization of isolated centrosomes

1987 • 292 citations

New data on the microtubule surface lattice

1991 • 250 citations

Structural changes accompanying GTP hydrolysis in microtubules: information from a slowly hydrolyzable analogue guanylyl-(alpha,beta)-methylene-diphosphonate.

1995 • 243 citations

Lattice defects in microtubules: protofilament numbers vary within individual microtubules

1992 • 236 citations

Microtubule Dynamic Instability and GTP Hydrolysis

1992 • 234 citations

Structural changes at microtubule ends accompanying GTP hydrolysis: Information from a slowly hydrolyzable analogue of GTP, guanylyl (α,β)methylenediphosphonate

1998 • 223 citations

MICROTUBULE SURFACE LATTICE AND SUBUNIT STRUCTURE AND OBSERVATIONS ON REASSEMBLY

1974 • 214 citations

Microtubules from Mammalian Brain: Some Properties of Their Depolymerization Products and a Proposed Mechanism of Assembly and Disassembly

1974 • 200 citations

Distinct roles of PP1 and PP2A-like phosphatases in control of microtubule dynamics during mitosis

1997 • 191 citations

Cold depolymerization of microtubules to double rings: geometric stabilization of assemblies

1989 • 183 citations

Dissociation of the Tubulin-sequestering and Microtubule Catastrophe-promoting Activities of Oncoprotein 18/Stathmin

1999 • 177 citations

The minimum GTP cap required to stabilize microtubules

1994 • 154 citations

Evidence that a single monolayer tubulin-GTP cap is both necessary and sufficient to stabilize microtubules.

1996 • 148 citations

Role of nucleotide hydrolysis in the dynamics of actin filaments and microtubules

1991 • 134 citations

Quantitative electron microscopy of microtubule assembly in vitro

1975 • 123 citations

Role of Nucleotide Hydrolysis in the Dynamics of Actin Filaments and Microtubules

1989 • 119 citations

Monte Carlo study of the GTP cap in a five-start helix model of a microtubule.

1985 • 114 citations

Microtubule dynamic instability: Numerical simulation of microtubule transition properties using a lateral cap model

1990 • 111 citations

GDP state of tubulin: stabilization of double rings

1986 • 111 citations

A Metastable Intermediate State of Microtubule Dynamic Instability That Differs Significantly between Plus and Minus Ends

1997 • 107 citations

Emerging techniques: Cryo-electron microscopy of vitrified biological specimens

1985 • 104 citations

The structure of microtubule ends during the elongation and shortening phases of dynamic instability examined by negative-stain electron microscopy

1990 • 94 citations

How Tubulin Subunits Are Lost from the Shortening Ends of Microtubules

1997 • 92 citations

Modeling elastic properties of microtubule tips and walls

1998 • 82 citations

Op18/Stathmin Mediates Multiple Region-Specific Tubulin and Microtubule-Regulating Activities

1999 • 64 citations

Buffer conditions and non‐tubulin factors critically affect the microtubule dynamic instability of sea urchin egg tubulin

1992 • 56 citations

The microtubule lattice — 20 years on

1995 • 49 citations

Microtubule's Conformational Cap.

1999 • 34 citations

Microtubule Instability and GTP Hydrolysis

1992 • 17 citations