Cells that constitutively express the herpes simplex virus immediate-early protein ICP4 allow efficient activation of viral delayed-early genes in trans

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

A Film Detection Method for Tritium‐Labelled Proteins and Nucleic Acids in Polyacrylamide Gels

1974 • 8,693 citations

Characteristics of a Human Cell Line Transformed by DNA from Human Adenovirus Type 5

1977 • 4,801 citations

Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids

1977 • 3,019 citations

Expression of a β-globin gene is enhanced by remote SV40 DNA sequences

1981 • 1,677 citations

Regulation of Herpesvirus Macromolecular Synthesis I. Cascade Regulation of the Synthesis of Three Groups of Viral Proteins

1974 • 1,479 citations

[17] Plasmid cloning vehicles derived from plasmids ColE1, F, R6K, and RK2

1979 • 508 citations

Control of herpes simplex virus type 1 mRNA synthesis in cells infected with wild-type virus or the temperature-sensitive mutant tsK

1979 • 496 citations

Monoclonal antibodies to herpes simplex virus type 1 proteins, including the immediate-early protein ICP 4

1981 • 436 citations

A herpes simplex virus type 1 function continuously required for early and late virus RNA synthesis

1980 • 429 citations

Characterization of the herpes simplex virion-associated factor responsible for the induction of alpha genes

1983 • 423 citations

Transcriptional activation of cloned human β-globin genes by viral immediate-early gene products

1983 • 373 citations

Regulation of herpesvirus macromolecular synthesis V. Properties of α polypeptides made in HSV-1 and HSV-2 infected cells

1977 • 253 citations

Herpes simplex virus phosphoproteins. I. Phosphate cycles on and off some viral polypeptides and can alter their affinity for DNA

1980 • 251 citations

Activation of gene expression by adenovirus and herpesvirus regulatory genes acting in trans and by a cis-acting adenovirus enhancer element

1983 • 250 citations

Altering Genotype and Phenotype by DNA-Mediated Gene Transfer

1980 • 242 citations

Evidence that herpes simplex virus DNA is transcribed by cellular RNA polymerase B

1977 • 163 citations

Separation and characterization of herpes simplex virus type 1 immediate-early mRNA's

1979 • 155 citations

Gene amplification and gene correction in somatic cells

1982 • 149 citations

Differentiation between alpha promoter and regulator regions of herpes simplex virus 1: the functional domains and sequence of a movable alpha regulator.

1982 • 148 citations

Regulation of herpesvirus macromolecular synthesis: transcription-initiation sites and domains of alpha genes.

1980 • 112 citations

Characterization of Herpes Simplex Virus Type 1 RNA Present in the Absence of De Novo Protein Synthesis

1980 • 101 citations

Functional analysis of a herpes simplex virus type 1 promoter: identification of far-upstream regulatory sequences

1983 • 98 citations

Glycoproteins of herpes simplex virus type 2 as defined by monoclonal antibodies

1982 • 92 citations

Location of the structural genes for glycoproteins gD and gE and for other polypeptides in the S component of herpes simplex virus type 1 DNA

1982 • 88 citations

DNA sequence elements required for regulated expression of the HSV-1 glycoprotein D gene lie within 83 bp of the RNA capsites

1983 • 82 citations

High-resolution characterization of herpes simplex virus type 1 transcripts encoding alkaline exonuclease and a 50,000-dalton protein tentatively identified as a capsid protein

1983 • 80 citations

DNA-Binding Proteins of Cells Infected by Herpes Simplex Virus Type 1 and Type 2

1976 • 77 citations

Orientation of herpes simplex virus type 1 immediate early mRNA's

1979 • 77 citations

Transcriptional regulation of a herpes simplex virus immediate early gene is mediated through an enhancer-type sequence.

1984 • 76 citations

Immunological characterization of herpes simplex virus type 1 and 2 polypeptide(s) involved in viral ribonucleotide reductase activity

1984 • 68 citations

Immediate-early mRNA-2 of herpes simplex viruses types 1 and 2 is unsplced: conserved sequences around the 5′ and 3′ termini correspond to transcription regulatory signals

1983 • 68 citations

DNA sequence of an Immediate-early gene (IE mRNA-5) of herpes simplex virus type I

1982 • 59 citations

Detailed structural analysis of two spliced HSV-1 immediate-early mRNAs

1982 • 56 citations

Expression of herpes simplex virus beta and gamma genes integrated in mammalian cells and their induction by an alpha gene product.

1983 • 56 citations

Herpes Simplex Virus Non-structural Proteins. IV. Purification of the Virus-induced Deoxyribonuclease and Characterization of the Enzyme Using Monoclonal Antibodies

1983 • 52 citations

Direct demonstration that the abundant 6-kilobase herpes simplex virus type 1 mRNA mapping between 0.23 and 0.27 map units encodes the major capsid protein VP5

1984 • 49 citations

Transactivation of a Late Herpes Simplex Virus Promoter

1984 • 40 citations

Positive control of the herpes simplex virus thymidine kinase gene requires upstream DNA sequences

1983 • 36 citations

Expression of Herpes Simplex Virus β and γ Genes Integrated in Mammalian Cells and Their Induction by an α Gene Product

1983 • 35 citations

Herpes simplex virus thymidine kinase transcripts are absent from both nucleus and cytoplasm during infection in the presence of cycloheximide

1980 • 29 citations

Successful Use of Oligopeptides as Immunogens in the Preparation of Antisera to Immediate-Early Gene Products of Herpes Simplex Virus Type 1

1984 • 10 citations

Inability to rescue viral genes from human cells biochemically transformed by herpes simplex virus type 2 DNA

1981 • 3 citations