A link between double-strand break-related repair and V(D)J recombination: the scid mutation.

QUANTITATIVE STUDIES OF THE GROWTH OF MOUSE EMBRYO CELLS IN CULTURE AND THEIR DEVELOPMENT INTO ESTABLISHED LINES

1963 • 2,742 citations

A severe combined immunodeficiency mutation in the mouse

1983 • 2,193 citations

X-ray induced DNA double strand break production and repair in mammalian cells as measured by neutral filter elution

1979 • 577 citations

Junctional sequences of T cell receptor γδ genes: Implications for γδ T cell lineages and for a novel intermediate of V-(D)-J joining

1989 • 572 citations

Rearrangement of antigen receptor genes is defective in mice with severe combined immune deficiency

1986 • 558 citations

The scid mutation in mice causes a general defect in DNA repair

1990 • 525 citations

The defect in murine severe combined immune deficiency: Joining of signal sequences but not coding segments in V(D)J recombination

1988 • 441 citations

X-ray sensitive mutants of Chinese hamster ovary cells defective in double-strand break rejoining

1984 • 379 citations

Deoxyribonucleic acid repair in the yeast Saccharomyces cerevisiae

1988 • 361 citations

Evidence of functional lymphocytes in some (leaky) scid mice.

1988 • 347 citations

X-ray-sensitive mutants of Chinese hamster ovary cell line isolation and cross-sensitivity to other DNA-damaging agents

1983 • 345 citations

Chromosome mutation and neoplasia

1983 • 290 citations

Evidence for a General Relationship between the Induced Level of DNA Double-strand Breakage and Cell-killing after X-irradiation of Mammalian Cells

1985 • 271 citations

Model of Tracks of Ionizing Radiations for Radical Reaction Mechanisms

1966 • 228 citations

Isolation and cross-sensitivity of X-ray-sensitive mutants of V79-4 hamster cells

1987 • 207 citations

Ataxia-telangiectasia: an inherited disorder of ionizing-radiation sensitivity in man

1987 • 200 citations

Enzyme action at 3' termini of ionizing radiation-induced DNA strand breaks.

1983 • 171 citations

Isolation of cell cycle-dependent gamma ray-sensitive Chinese hamster ovary cell

1983 • 170 citations

Cell cycle-dependent repair of double-strand DNA breaks in a ?-ray-sensitive Chinese hamster cell

1985 • 150 citations

Isolation of scid pre-B cells that rearrange kappa light chain genes: formation of normal signal and abnormal coding joins.

1989 • 128 citations

Fungal recombination

1985 • 121 citations

The mechanism of antigen receptor gene assembly

1989 • 108 citations

¹²⁵I-induced DNA Double Strand Breaks: Use in Calibration of the Neutral Filter Elution Technique and Comparison with X-ray Induced Breaks

1985 • 99 citations

The scid gene encodes a trans-acting factor that mediates the rejoining event of Ig gene rearrangement.

1988 • 94 citations

Classification of chemical agents as to their ability to induce long-or short-patch DNA repair in human cells

1981 • 89 citations

Characterization of an X-ray-hypersensitive mutant of V79 Chinese hamster cells

1988 • 83 citations

Wild-type V(D)J recombination in scid pre-B cells.

1990 • 53 citations

A quantitative assay of deoxyribonucleic acid strand breaks and their repair in mammalian cells

1982 • 50 citations

Normal recombination substrate VH to DJH rearrangements in pre-B cell lines from scid mice.

1990 • 49 citations

Physical Basis for Detection of DNA Double-Strand Breaks Using Neutral Filter Elution

1990 • 40 citations

Wild-Type V(D)J Recombination in scid Pre-B Cells

1990 • 16 citations