Association of Bax and Bak Homo-oligomers in Mitochondria

Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade

1997 • 7,177 citations

Induction of Apoptotic Program in Cell-Free Extracts: Requirement for dATP and Cytochrome c

1996 • 5,133 citations

Cleavage of BID by Caspase 8 Mediates the Mitochondrial Damage in the Fas Pathway of Apoptosis

1998 • 4,383 citations

Proapoptotic BAX and BAK: A Requisite Gateway to Mitochondrial Dysfunction and Death

2001 • 3,867 citations

Bid, a Bcl2 Interacting Protein, Mediates Cytochrome c Release from Mitochondria in Response to Activation of Cell Surface Death Receptors

1998 • 3,603 citations

Serine Phosphorylation of Death Agonist BAD in Response to Survival Factor Results in Binding to 14-3-3 Not BCL-XL

1996 • 2,627 citations

Bax-Deficient Mice with Lymphoid Hyperplasia and Male Germ Cell Death

1995 • 1,500 citations

The Combined Functions of Proapoptotic Bcl-2 Family Members Bak and Bax Are Essential for Normal Development of Multiple Tissues

2000 • 1,427 citations

Bid-induced Conformational Change of Bax Is Responsible for Mitochondrial Cytochrome c Release during Apoptosis

1999 • 1,255 citations

tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c

2000 • 1,245 citations

Cytosol-to-membrane redistribution of Bax and Bcl-X_Lduring apoptosis

1997 • 1,117 citations

Structure of Bax

2000 • 1,066 citations

Breaking the mitochondrial barrier

2001 • 947 citations

Life-or-death decisions by the Bcl-2 protein family

2001 • 887 citations

Role ofBAXin the Apoptotic Response to Anticancer Agents

2000 • 854 citations

Conformation of the Bax C-terminus regulates subcellular location and cell death

1999 • 723 citations

Bax Is Present as a High Molecular Weight Oligomer/Complex in the Mitochondrial Membrane of Apoptotic Cells

2001 • 676 citations

Bax-induced Cytochrome C Release from Mitochondria Is Independent of the Permeability Transition Pore but Highly Dependent on Mg2+ Ions

1998 • 645 citations

Bax oligomerization is required for channel-forming activity in liposomes and to trigger cytochrome c release from mitochondria

2000 • 619 citations

Nonionic Detergents Induce Dimerization among Members of the Bcl-2 Family

1997 • 583 citations

Bax in Murine Thymus Is a Soluble Monomeric Protein That Displays Differential Detergent-induced Conformations

1998 • 508 citations

The role of the Bcl-2 family in the regulation of outer mitochondrial membrane permeability

2000 • 493 citations

Bax and Bak Coalesce into Novel Mitochondria-Associated Clusters during Apoptosis

2001 • 466 citations

TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO

2002 • 448 citations

BAX-dependent transport of cytochrome c reconstituted in pure liposomes

2000 • 447 citations

Solution structure of the antiapoptotic protein bcl-2

2001 • 433 citations

Bcl-2 Prevents Bax Oligomerization in the Mitochondrial Outer Membrane

2001 • 320 citations

Role of hypoxia-induced Bax translocation and cytochrome c release in reoxygenation injury

1998 • 294 citations

TNF-α Signals Apoptosis through a Bid-Dependent Conformational Change in Bax that Is Inhibited by E1B 19K

2000 • 196 citations

Bax and Bak Independently Promote Cytochrome cRelease from Mitochondria

2002 • 188 citations

Bcl-2 Inhibits a Fas-induced Conformational Change in the Bax N Terminus and Bax Mitochondrial Translocation

2000 • 121 citations

Tumor Necrosis Factor-α Induces Bax-Bak Interaction and Apoptosis, Which Is Inhibited by Adenovirus E1B 19K

2001 • 119 citations

REGULATORS OF APOPTOSIS ON THE ROAD TO PERSISTENT ALPHAVIRUS INFECTION

1997 • 99 citations

E1B 19K Blocks Bax Oligomerization and Tumor Necrosis Factor Alpha-Mediated Apoptosis

2001 • 90 citations

Subcellular Distribution and Redistribution of Bcl-2 Family Proteins in Human Leukemia Cells Undergoing Apoptosis

1999 • 90 citations

Bak and Bax Function To Limit Adenovirus Replication through Apoptosis Induction

2002 • 85 citations

Elimination of bax expression in mice increases cerebellar purkinje cell numbers but not the number of granule cells

2001 • 77 citations

Serine protease inhibitors suppress cytochrome c-mediated caspase-9 activation and apoptosis during hypoxia‒reoxygenation

2000 • 75 citations

Subcellular localization of SV2 and other secretory vesicle components in PC12 cells by an efficient method of preembedding EM immunocytochemistry for cell cultures.

1996 • 74 citations

Serine protease inhibitors suppress cytochrome c-mediated caspase-9 activation and apoptosis during hypoxia–reoxygenation

2000 • 43 citations