A urokinase-sensitive region of the human urokinase receptor is responsible for its chemotactic activity

Interleukin-8 and related chemotactic cytokines--CXC and CC chemokines.

1994 • 2,251 citations

Receptor-Dependent Mechanisms of Cell Stimulation by Bacterial Endotoxin

1995 • 1,436 citations

Heterotrimeric C proteins: Organizers of transmembrane signals

1995 • 1,388 citations

Regulation of Integrin Function by the Urokinase Receptor

1996 • 734 citations

Cloning and expression of the receptor for human urokinase plasminogen activator, a central molecule in cell surface, plasmin dependent proteolysis.

1990 • 624 citations

Cellular receptor for urokinase plasminogen activator. Carboxyl-terminal processing and membrane anchoring by glycosyl-phosphatidylinositol

1991 • 578 citations

The receptor-binding sequence of urokinase. A biological function for the growth-factor module of proteases.

1987 • 479 citations

Differentiation-enhanced binding of the amino-terminal fragment of human urokinase plasminogen activator to a specific receptor on U937 monocytes.

1985 • 450 citations

Urokinase-type plasminogen activator is expressed in stromal cells and its receptor in cancer cells at invasive foci in human colon adenocarcinomas.

1991 • 440 citations

Autocrine saturation of pro-urokinase receptors on human A431 cells

1986 • 361 citations

Urokinase plasminogen activator receptor, beta 2-integrins, and Src-kinases within a single receptor complex of human monocytes.

1995 • 355 citations

Mutants of Pertussis Toxin Suitable for Vaccine Development

1989 • 318 citations

The urokinase receptor is required for human monocyte chemotaxis in vitro.

1994 • 308 citations

Proteolytic cleavage of the urokinase receptor substitutes for the agonist-induced chemotactic effect.

1996 • 306 citations

Induction of cell migration by pro-urokinase binding to its receptor: possible mechanism for signal transduction in human epithelial cells.

1994 • 266 citations

The ligand-binding domain of the cell surface receptor for urokinase-type plasminogen activator.

1991 • 256 citations

Urokinase plasminogen activator cleaves its cell surface receptor releasing the ligand-binding domain.

1992 • 253 citations

Structure—function relationships in the receptor for urokinase‐type plasminogen activator Comparison to other members of the Ly‐6 family and snake venom α‐neurotoxins

1994 • 252 citations

Urokinase receptor antagonists inhibit angiogenesis and primary tumor growth in syngeneic mice.

1996 • 250 citations

Characterization of the Cellular Binding Site for the Urokinase-type Plasminogen Activator

1989 • 248 citations

uPA, uPAR, PAI-I: Key intersection of proteolytic, adhesive and chemotacfic highways?

1997 • 246 citations

The Urokinase Receptor. Protein Structure and Role in Plasminogen Activation and Cancer Invasion

1995 • 235 citations

Generation and characterization of urokinase receptor-deficient mice.

1996 • 232 citations

Surface receptors for urokinase plasminogen activator

1988 • 222 citations

Receptor for urokinase is present in tumor-associated macrophages in ductal breast carcinoma.

1993 • 192 citations

Urokinase is required for the pulmonary inflammatory response to Cryptococcus neoformans. A murine transgenic model.

1996 • 188 citations

Prognostic significance of the receptor for urokinase plasminogen activator in breast cancer.

1995 • 175 citations

Urokinase receptor. An activation antigen in human T lymphocytes.

1994 • 172 citations

The Receptor-Binding Sequence of Urokinase

1987 • 167 citations

The urokinase receptor is expressed in invasive breast cancer but not in normal breast tissue.

1994 • 153 citations

Regulation of urokinase receptors in monocytelike U937 cells by phorbol ester phorbol myristate acetate.

1989 • 142 citations

Urokinase-type plasminogen activator receptor reversibly dissociates from complement receptor type 3 (alpha M beta 2' CD11b/CD18) during neutrophil polarization.

1996 • 134 citations

Induction of primary cutaneous melanocytic neoplasms in urokinase-type plasminogen activator (uPA)-deficient and wild-type mice: cellular blue nevi invade but do not progress to malignant melanoma in uPA-deficient animals.

1996 • 125 citations

Cell‐Surface Acceleration of Urokinase‐Catalyzed Receptor Cleavage

1997 • 120 citations

Ligand Interaction between Urokinase-Type Plasminogen Activator and Its Receptor Probed with 8-Anilino-1-naphthalenesulfonate. Evidence for a Hydrophobic Binding Site Exposed Only on the Intact Receptor

1994 • 102 citations

Interaction of urokinase with specific receptors stimulates mobilization of bovine adrenal capillary endothelial cells*1

1988 • 98 citations

Integrin-dependent induction of functional urokinase receptors in primary T lymphocytes.

1996 • 95 citations

Human urokinase-type plasminogen activator stimulates chemotaxis of human neutrophils

1987 • 92 citations

A cleaved form of the receptor for urokinase‐type plasminogen activator in invasive transplanted human and murine tumors

1994 • 89 citations

Acidic sphingomyelinase-generated ceramide is needed but not sufficient for TNF-induced apoptosis and nuclear factor-kappa B activation.

1996 • 81 citations

A soluble, ligand binding mutant of the human urokinase plasminogen activator receptor

1991 • 65 citations

A common multiple cloning site in a set of vectors for expression of eukaryotic genes in mammalian, insect and bacterial cells

1994 • 11 citations