Urokinase receptor antagonists inhibit angiogenesis and primary tumor growth in syngeneic mice.

On a Test of Whether one of Two Random Variables is Stochastically Larger than the Other

1947 • 12,091 citations

Angiogenesis in cancer, vascular, rheumatoid and other disease

1995 • 7,717 citations

Calculation of protein extinction coefficients from amino acid sequence data

1989 • 5,198 citations

Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo

1993 • 3,605 citations

Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant

1994 • 1,249 citations

Dual regulation of vascular endothelial growth factor bioavailability by genetic and proteolytic mechanisms.

1992 • 1,145 citations

Antibodies to plasminogen activator inhibit human tumor metastasis

1983 • 651 citations

Identification of the urokinase receptor as an adhesion receptor for vitronectin.

1994 • 593 citations

THE ROLE OF ENDOTOXIN IN THE EXTRACELLULAR COAGULATION OF LIMULUS BLOOD.

1964 • 464 citations

The opposing effects of basic fibroblast growth factor and transforming growth factor beta on the regulation of plasminogen activator activity in capillary endothelial cells.

1987 • 378 citations

Upregulation of urokinase receptor expression on migrating endothelial cells

1993 • 277 citations

Characterization of the Cellular Binding Site for the Urokinase-type Plasminogen Activator

1989 • 248 citations

Biological Activation of pro-HGF (Hepatocyte Growth Factor) by Urokinase Is Controlled by a Stoichiometric Reaction

1995 • 248 citations

Plasminogen activator inhibitor-1 and prognosis in primary breast cancer.

1994 • 230 citations

Complexes of polyoma virus medium T antigen and cellular proteins.

1985 • 223 citations

Enhanced Tumor Growth of Both Primary and Established Human and Murine Tumor Cells in Athymic Mice After Coinjection With Matrigel

1991 • 216 citations

In vivo patterns of expression of urokinase and its inhibitor PAI-1 suggest a concerted role in regulating physiological angiogenesis.

1992 • 187 citations

Role of the SIKVAV Site of Laminin in Promotion of Angiogenesis and Tumor Growth: An In Vivo Matrigel Model

1992 • 185 citations

Urokinase‐type plasminogen activator mediates basic fibroblast growth factor‐induced bovine endothelial cell migration independent of its proteolytic activity

1992 • 183 citations

Inhibition of urokinase-type plasminogen activator by antibodies: the effect on dissemination of a human tumor in the nude mouse.

1991 • 179 citations

Expression of the urokinase receptor in vascular endothelial cells is stimulated by basic fibroblast growth factor.

1991 • 178 citations

Molecular cloning and expression of a G25K cDNA, the human homolog of the yeast cell cycle gene CDC42.

1990 • 172 citations

The urokinase receptor is expressed in invasive breast cancer but not in normal breast tissue.

1994 • 153 citations

Plasminogen activators, their inhibitors, and urokinase receptor emerge in late stages of melanocytic tumor progression.

1994 • 150 citations

Co‐expression of urokinase, urokinase receptor and PAI‐1 is necessary for optimum invasiveness of cultured lung cancer cells

1995 • 146 citations

Urokinase-type plasminogen activator and its receptor: new targets for anti-metastatic therapy?

1994 • 139 citations

Urokinase and macrophages in tumour angiogenesis

1995 • 121 citations

cDNA for Mo3, a monocyte activation antigen, encodes the human receptor for urokinase plasminogen activator.

1992 • 89 citations

Inhibition of the Metastasis of Lewis Lung Carcinoma by Antibody Against Urokinase-Type Plasminogen Activator in the Experimental and Spontaneous Metastasis Model

1994 • 61 citations

Domain analysis of urokinase plasminogen activator (u-PA): Preparation and characterization of intact A-chain molecules

1992 • 29 citations

Perturbations in the fibrinolytic pathway abolish cyst formation but not capillary-like organization of cultured murine endothelial cells

1994 • 21 citations

Yeast expression and phagemid display of the human urokinase plasminogen activator epidermal growth factor-like domain

1995 • 21 citations

Expression of plasminogen activators and plasminogen activator inhibitors in cutaneous melanomas of transgenic melanoma-susceptible mice.

1995 • 19 citations