A second tyrosinase-related protein, TRP-2, maps to and is mutated at the mouse slaty locus.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

1988 • 17,059 citations

A new method for predicting signal sequence cleavage sites

1986 • 4,629 citations

Prosite: a dictionary of sites and patterns in proteins

1992 • 952 citations

Organization, distribution, and stability of endogenous ecotropic murine leukemia virus DNA sequences in chromosomes of Mus musculus

1982 • 611 citations

An lmproved method for directly sequencing PCR-amplified material using dimethyl sulphoxide

1989 • 608 citations

Mammalian Tyrosinase Catalyzes Three Reactions in the Biosynthesis of Melanin

1982 • 574 citations

A second tyrosinase-related protein, TRP-2, is a melanogenic enzyme termed DOPAchrome tautomerase.

1992 • 552 citations

Novel myosin heavy chain encoded by murine dilute coat colour locus

1991 • 534 citations

X-RAY-INDUCED MUTATIONS IN MICE

1951 • 486 citations

Development and applications of a molecular genetic linkage map of the mouse genome

1991 • 427 citations

Linkage, recombination and mapping

1981 • 279 citations

Functional analysis of alternatively spliced tyrosinase gene transcripts.

1988 • 275 citations

Reexamination of the structure of eumelanin

1986 • 268 citations

A cDNA encoding tyrosinase-related protein maps to the brown locus in mouse.

1988 • 247 citations

New regulators of melanin biosynthesis and the autodestruction of melanoma cells

1980 • 244 citations

Cloning and expression of cDNA encoding mouse tyrosinase

1986 • 241 citations

The gene Serrate encodes a putative EGF-like transmembrane protein essential for proper ectodermal development in Drosophila melanogaster.

1990 • 222 citations

Conserved cysteine to serine mutation in tyrosinase is responsible for the classical albino mutation in laboratory mice

1990 • 209 citations

The many faces of epidermal growth factor repeats.

1990 • 197 citations

Dopachrome Conversion: A Possible Control Point in Melanin Biosynthesis

1980 • 190 citations

5,6-Dihydroxyindole is a melanin precursor showing potent cytotoxicity

1978 • 187 citations

The Drosophila gene Serrate encodes an EGF-like transmembrane protein with a complex expression pattern in embryos and wing discs

1991 • 179 citations

Regulation of mammalian melanogenesis I: partial purification and characterization of a dopachrome converting factor: dopachrome tautomerase

1990 • 175 citations

The molecular basis of brown, an old mouse mutation, and of an induced revertant to wild type.

1990 • 162 citations

Dopachrome Oxidoreductase: A New Enzyme in the Pigment Pathway

1984 • 133 citations

Melanin production in cultured albino melanocytes transfected with mouse tyrosinase cDNA.

1989 • 111 citations

Melanization in albino mice transformed by introducing cloned mouse tyrosinase gene

1990 • 110 citations

A point mutation in the tyrosinase gene of BALB/c albino mouse causing the cysteine → serine substitution at position 85

1990 • 110 citations

Dopachrome conversion factor functions as an isomerase

1990 • 96 citations

Detection of Mutations in the Tyrosinase Gene in a Patient with Type IA Oculocutaneous Albinism

1990 • 92 citations

Tyrosinase gene mutations associated with type IB ("yellow") oculocutaneous albinism.

1991 • 92 citations

Identification of the albino mutation of mouse tyrosinase by analysis of an in vitro revertant.

1990 • 87 citations

The tyrosinase-related protein-1 gene has a structure and promoter sequence very different from tyrosinase

1991 • 85 citations

Characterization of TRP-1 mRNA levels in dominant and recessive mutations at the mouse brown (b) locus.

1990 • 82 citations

A frequent tyrosinase gene mutation in classic, tyrosinase-negative (type IA) oculocutaneous albinism.

1990 • 75 citations

Molecular basis of tyrosinase-negative oculocutaneous albinism. A single base mutation in the tyrosinase gene causing arginine to glutamine substitution at position 59.

1990 • 75 citations

Functional analysis of the cDNA encoding human tyrosinase precursor

1989 • 74 citations

Phenotypic rescue of mutant brown melanocytes by a retrovirus carrying a wild-type tyrosinase-related protein gene

1990 • 72 citations

The many faces of epidermal growth factor repeats.

1990 • 68 citations

Isolation, Chromosomal Mapping, and Expression of the Mouse Tyrosinase Gene

1989 • 60 citations

Mouse coat colour mutations: A molecular genetic resource which spans the centuries

1991 • 47 citations

Homozygous tyrosinase gene mutation in an American black with tyrosinase-negative (type IA) oculocutaneous albinism.

1991 • 43 citations

An interspecific backcross linkage map of the proximal half of mouse chromosome 14

1990 • 42 citations

Molecular Analysis of an Extended Family with Type IA (Tyrosinase-Negative) Oculocutaneous Albinism

1991 • 38 citations

Detection of point mutation in the tyrosinase gene of a Japanese albino patient by a direct sequencing of amplified DNA

1990 • 38 citations

Three different frameshift mutations of the tyrosinase gene in type IA oculocutaneous albinism.

1991 • 38 citations

New regulatory factors for melanogenesis: Developmental changes in neonatal mice of various genotypes

1983 • 27 citations