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A Heteroskedasticity-Consistent Covariance Matrix Estimator and a Direct Test for Heteroskedasticity

1980 • 25,774 citations

Insulin-Like Growth Factors and Their Binding Proteins: Biological Actions*

1995 • 4,419 citations

REPRODUCIBILITY AND VALIDITY OF A SEMIQUANTITATIVE FOOD FREQUENCY QUESTIONNAIRE

1985 • 4,150 citations

Plasma Insulin-Like Growth Factor-I and Prostate Cancer Risk: A Prospective Study

1998 • 2,010 citations

Circulating concentrations of insulin-like growth factor I and risk of breast cancer

1998 • 1,850 citations

Insulin-Like Growth Factors I and II. Peptide, Messenger Ribonucleic Acid and Gene Structures, Serum, and Tissue Concentrations*

1989 • 1,796 citations

Nutritional Regulation of the Insulin-Like Growth Factors*

1994 • 1,537 citations

The Use of Estrogens and Progestins and the Risk of Breast Cancer in Postmenopausal Women

1995 • 1,532 citations

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1999 • 1,495 citations

Population Marginal Means in the Linear Model: An Alternative to Least Squares Means

1980 • 1,428 citations

Role of the Insulin-Like Growth Factor Family in Cancer Development and Progression

2000 • 1,414 citations

A prospective study of dietary glycemic load, carbohydrate intake, and risk of coronary heart disease in US women

2000 • 1,190 citations

The glycemic index: methodology and clinical implications

1991 • 1,156 citations

Prospective Study of Colorectal Cancer Risk in Men and Plasma Levels of Insulin-Like Growth Factor (IGF)-I and IGF-Binding Protein-3

1999 • 1,128 citations

Menopausal Estrogen and Estrogen-Progestin Replacement Therapy and Breast Cancer Risk

2000 • 1,075 citations

Physical Activity, Obesity, and Risk for Colon Cancer and Adenoma in Men

1995 • 1,014 citations

Insulin‐like growth factors I and II

1990 • 1,006 citations

Reproducibility and Validity of a Self-Administered Physical Activity Questionnaire

1994 • 998 citations

Insulin-Like Growth Factors

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Effect of Hormone Replacement Therapy on Breast Cancer Risk: Estrogen Versus Estrogen Plus Progestin

2000 • 879 citations

Insulin-Like Growth Factor 1 and Prostate Cancer Risk: A Population-Based, Case-Control Study

1998 • 592 citations

Plasma Levels of Insulin-Like Growth Factor-I and Lung Cancer Risk: a Case-Control Analysis

1999 • 558 citations

Alcohol, Height, and Adiposity in Relation to Estrogen and Prolactin Levels in Postmenopausal Women

1995 • 556 citations

Dietary glycemic load assessed by food-frequency questionnaire in relation to plasma high-density-lipoprotein cholesterol and fasting plasma triacylglycerols in postmenopausal women

2001 • 460 citations

Serum levels of insulin-like growth factor (IGF)-binding protein-3 (IGFBP-3) in healthy infants, children, and adolescents: the relation to IGF-I, IGF-II, IGFBP-1, IGFBP-2, age, sex, body mass index, and pubertal maturation.

1995 • 439 citations

Dietary restriction reduces insulin-like growth factor I levels, which modulates apoptosis, cell proliferation, and tumor progression in p53-deficient mice.

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A prospective study of plasma insulin-like growth factor-1 and binding protein-3 and risk of colorectal neoplasia in women.

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Association of Dietary Intake of Fat and Fatty Acids With Risk of Breast Cancer

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Estrogen Replacement Therapy and Risk of Fatal Colon Cancer in a Prospective Cohort of Postmenopausal Women

1995 • 364 citations

Reproductive Risk Factors in a Prospective Study of Breast Cancer: The Nurses' Health Study

1994 • 360 citations

Serum insulin-like growth factor-I and breast cancer

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Serum insulin‐like growth factor I in a random population sample of men and women: relation to age, sex, smoking habits, coffee consumption and physical activity, blood pressure and concentrations of plasma lipids, fibrinogen, parathyroid hormone and osteocalcin

1994 • 343 citations

Genetic and environmental components of interindividual variation in circulating levels of IGF-I, IGF-II, IGFBP-1, and IGFBP-3.

1996 • 330 citations

Insulin-like growth factor physiology and cancer risk

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Physical activity, obesity, and risk of colorectal adenoma in women (United States)

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Effect of Tamoxifen on Serum Insulinlike Growth Factor I Levels in Stage I Breast Cancer Patients

1990 • 264 citations

Photoperiodic Effects on Dairy Cattle: A Review

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Nutrition and prostate cancer

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Serum Total IGF-I, Free IGF-I, and IGFBP-1 Levels in an Elderly Population

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Epidemiology of Insulin-like Growth Factor-I in Elderly Men and Women: The Rancho Bernardo Study

1997 • 241 citations

Dietary Changes Favorably Affect Bone Remodeling in Older Adults

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Postmenopausal Hormone Use and Risk of Large-Bowel Cancer

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Relationship between dietary fat and experimental mammary tumorigenesis: a review and critique.

1992 • 232 citations

The ratio between serum levels of insulin‐like growth factor (IGF)‐I and the IGF binding proteins (IGFBP‐1, 2 and 3) decreases with age in healthy adults and is increased in acromegalic patients

1994 • 232 citations

Parity, age at first and last birth, and risk of breast cancer: A population-based study in Sweden

1996 • 221 citations

Serum Levels of Insulin-Like Growth Factor I (IGF-I), IGF-II, IGF-Binding Protein-3, and Prostate-Specific Antigen as Predictors of Clinical Prostate Cancer

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Insulin‐like growth‐factor‐binding protein 3 is decreased in early‐stage operable pre‐menopausal breast cancer

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Dairy products, calcium, phosphorous, vitamin D, and risk of prostate cancer (Sweden)

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Bovine Growth Hormone: Human Food Safety Evaluation

1990 • 192 citations

IGF-I and IGF-II in relation to colorectal cancer

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Nutrition, social factors and prostatic cancer in a Northern Italian population

1986 • 189 citations

Insulin-like growth factors (IGF-I, free IGF-I, and IGF-II) and insulin-like growth factor binding proteins (IGFBP-2, IGFBP-3, IGFBP-6, and ALS) in blood circulation

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Milk Intake, Circulating Levels of Insulin-Like Growth Factor-I, and Risk of Colorectal Cancer in Men

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Insulin and Insulin‐like Growth Factor 1 Stimulate Proliferation of Metastatic Variants of Colon Carcinoma 26

1989 • 181 citations

Animal products, calcium and protein and prostate cancer risk in the Netherlands Cohort Study

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Hormone replacement therapy, reproductive history, and colon cancer: a multicenter, case-control study in the United States.

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Recreational and Occupational Physical Activities and Risk of Breast Cancer

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Diet and prostatic cancer: A case‐control study in northern Italy

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Effect of Dietary Protein Deprivation on Insulin-Like Growth Factor (IGF)-I and -II, IGF Binding Protein-2, and Serum Albumin Gene Expression in Rat*

1990 • 148 citations

A meta-analysis of hormone replacement therapy and colon cancer in women.

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Presence of somatomedin receptors on primary human breast and colon carcinomas

1987 • 141 citations

Clinical Uses of Insulin-like Growth Factor I

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Net Energy Effects of Dietary Fat on Chemically Induced Mammary Carcinogenesis in F344 Rats<xref ref-type="fn" rid="FN2">2</xref>

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Dietary Fat and Carbohydrates Are Independently Associated With Circulating Insulin-Like Growth Factor 1 and Insulin-Like Growth Factor–Binding Protein 3 Concentrations in Healthy Adults

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Reduced mammary gland carcinogenesis in transgenic mice expressing a growth hormone antagonist

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Differential effects of oral conjugated estrogens and transdermal estradiol on insulin-like growth factor 1, growth hormone and sex hormone binding globulin serum levels

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Down-Regulation of the Serum Stimulatory Components of the Insulin-like Growth Factor (IGF) System (IGF-I, IGF-II, IGF Binding Protein [BP]-3, and IGFBP-5) in Age-Related (Type II) Femoral Neck Osteoporosis

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Age, Sex, and Smoking Are Predictors of Circulating Insulin-Like Growth Factor 1 and Insulin-Like Growth Factor–Binding Protein 3

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Age-Related Changes in Serum Insulin-Like Growth Factor-Binding Proteins in Women*

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The growth hormone: insulin-like growth factor 1 axis is a mediator of diet restriction-induced inhibition of mononuclear cell leukemia in Fischer rats.

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Association of Insulin‐Like Growth Factor‐I with Body Composition, Weight History, and Past Health Behaviors in the Very Old: The Framingham Heart Study

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Low somatomedin-C levels in older men rise in response to growth hormone administration.

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Reproductive factors and risk of brain, colon, and other malignancies in Iowa (United States)

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Insulin-like growth factors and their binding proteins in plasma and milk after growth hormone-stimulated galactopoiesis in normally lactating women

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Circulating Insulin-Like Growth Factor II and Colorectal Adenomas*

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Dietary Fat Intake and Endogenous Sex Steroid Hormone Levels in Postmenopausal Women

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Dairy Products and the Risk of Prostatic Cancer

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Growth of artificially fed infant rats: effect of supplementation with insulin-like growth factor I

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Nutritional regulation of IGF-I and IGFBPs.

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Effect of replacement estrogen on insulin-like growth factor-I in postmenopausal women: the Rancho Bernardo Study.

1996 • 50 citations

Insulin-like growth factor-I and insulin-like growth factor binding protein-3 inhibit involution of the mammary gland following lactation: Studies in transgenic mice

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Quantitative assessment of fat and calorie as risk factors in mammary carcinogenesis in an experimental model.

1990 • 36 citations

Differential effects of estrogen and medroxyprogesterone on basal and stress-induced growth hormone release, IGF-1 levels, and cellular immunity in postmenopausal women

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Parity and Colorectal Cancer Risk in Women<xref ref-type="fn" rid="fn2">2</xref>

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Metabolic Effects of Hypopituitarism and Acromegaly<sup>1</sup>

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Plasma Insulin-Like Growth Factor-I and Its Binding Proteins 1 and 3 During Continuous Nonoral and Oral Combined Hormone Replacement Therapy

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Recent progress in research on nutrition and cancer : proceedings of a workshop sponsored by the International Union Against Cancer, held in Nagoya, Japan, November 1-3, 1989

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Secretion of Insulin-Like Growth Factor-II into Bile of Rats of Different Ages

2000 • 1 citations