Expression of adenovirus E1a and E1b gene products and the Escherichia coli XGPRT gene in KB cells

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

Selective extraction of polyoma DNA from infected mouse cell cultures

1967 • 5,357 citations

Characteristics of a Human Cell Line Transformed by DNA from Human Adenovirus Type 5

1977 • 4,801 citations

Screening λgt Recombinant Clones by Hybridization to Single Plaques in Situ

1977 • 4,696 citations

Amino Acid Metabolism in Mammalian Cell Cultures

1959 • 4,025 citations

Efficient transfer of large DNA fragments from agarose gels to diazobenzyloxymethyl-paper and rapid hybridization by using dextran sulfate.

1979 • 3,525 citations

Transformation of mammalian cells with genes from procaryotes and eucaryotes

1979 • 1,474 citations

Transfer of purified herpes virus thymidine kinase gene to cultured mouse cells

1977 • 1,411 citations

Selection for animal cells that express the Escherichia coli gene coding for xanthine-guanine phosphoribosyltransferase.

1981 • 1,048 citations

An adenovirus type 5 early gene function regulates expression of other early viral genes.

1979 • 791 citations

Expression of a Bacterial Gene in Mammalian Cells

1980 • 788 citations

Isolation of adenovirus type 5 host range deletion mutants defective for transformation of rat embryo cells

1979 • 785 citations

A new dominant hybrid selective marker for higher eukaryotic cells

1981 • 662 citations

Mechanism of activation of early viral transcription by the adenovirus E1A gene product

1981 • 604 citations

Transcriptional control in the production of liver-specific mRNAs

1981 • 593 citations

Structure of the adenovirus 2 early mRNAs

1978 • 591 citations

Complex splicing patterns of RNAs from the early regions of adenovirus-2

1979 • 560 citations

GENETICS OF HUMAN CELL LINES, IV. DNA-MEDIATED HERITABLE TRANSFORMATION OF A BIOCHEMICAL TRAIT

1962 • 493 citations

Mapping temperature-sensitive and host-range mutations of adenovirus type 5 by marker rescue

1978 • 408 citations

The transfer and stable integration of the HSV thymidine kinase gene into mouse cells

1978 • 382 citations

Effect of Growth Conditions on the Formation of the Relaxation Complex of Supercoiled ColE1 Deoxyribonucleic Acid and Protein in Escherichia coli

1972 • 351 citations

Host-range mutants of adenovirus type 5 defective for growth in HeLa cells

1977 • 330 citations

Gene Amplification and Drug Resistance in Cultured Murine Cells

1978 • 317 citations

Transfer of Thymidine Kinase to Thymidine Kinaseless L Cells by Infection with Ultraviolet-Irradiated Herpes Simplex Virus

1971 • 268 citations

Selection and Preliminary Characterization of Temperature-Sensitive Mutants of Type 5 Adenovirus

1972 • 248 citations

Transfer of the gene for thymidine kinase to thymidine kinase-deficient human cells by purified herpes simplex viral DNA.

1977 • 246 citations

Integrated simian virus 40 sequences in transformed cell DNA: analysis using restriction endonucleases.

1976 • 229 citations

Mechanisms and applications of DNA-mediated gene transfer in mammalian cells — a review

1981 • 188 citations

Translation of rabbit globin mRNA introduced by liposomes into mouse lymphocytes

1978 • 184 citations

The structure of adenovirus 2 early nuclear and cytoplasmic RNAs

1980 • 177 citations

Characteristics of an SV40-plasmid recombinant and its movement into and out of the genome of a murine cell

1980 • 164 citations

Enhancement of Adenovirus Plaque Formation on HeLa Cells by Magnesium Chloride

1970 • 164 citations

Functional Analysis of Adenovirus-5 Host-range Deletion Mutants Defective for Transformation of Rat Embryo Cells

1980 • 162 citations

Transformation of mammalian cells with an amplifiable dominant-acting gene.

1980 • 158 citations

Intracellular Uncoating of Type 5 Adenovirus Deoxyribonucleic Acid

1967 • 141 citations

Parameters governing the transfer of the genes for thymidine kinase and dihydrofolate reductase into mouse cells using metaphase chromosomes or DNA

1980 • 139 citations

[70] Definition and mapping of adenovirus 2 nuclear transcription

1980 • 136 citations

Proteins and messenger RNAs of the transforming region of wild-type and mutant adenoviruses

1980 • 132 citations

Analysis of type 5 adenovirus transformation with a cloned rat embryo cell line (CREF).

1982 • 126 citations

Factors governing the expression of a bacterial gene in mammalian cells.

1981 • 126 citations

Transformation-defective mutant of adenovirus type 5 containing a single altered E1a mRNA species

1981 • 123 citations

Mapping of early SV40-specific functions by microinjection of different early viral DNA fragments

1978 • 113 citations

Conversion of bacteriophage fd into an efficient single-stranded DNA vector system

1980 • 111 citations

Transformation-deficient adenovirus mutant defective in expression of region 1A but not region 1B

1982 • 78 citations

Co-expression and amplification of dihydrofolate reductase cDNA and the Escherichia coli XGPRT gene in Chinese hamster ovary cells.

1981 • 75 citations

Expression of unselected adenovirus genes in human cells co-transformed with the HSV-1 tk gene and adenovirus 2 DNA

1980 • 66 citations

Intraspecies transfer via total cellular DNA of the gene for hypoxanthine phosphoribosyltransferase into cultured mouse cells

1979 • 62 citations

DNA-mediated gene transfer of a circular plasmid into murine cells.

1979 • 54 citations

Non-Chromosomal Antibiotic Resistance in Bacteria, III: Isolation of the Discrete Transfer Unit of the R-Factor R1

1970 • 50 citations

CHROMOSOME-MEDIATED GENE TRANSFER IN MAMMALIAN CELLS

1980 • 48 citations

Factors Governing the Expression of a Bacterial Gene in Mammalian Cells

1981 • 45 citations

Proteins containing only half of the coding information of early region 1b of adenovirus are functional in human cells transformed with the herpes simplex virus type 1 thymidine kinase gene and adenovirus type 2 DNA

1982 • 10 citations

Red cell-mediated microinjection.

1978 • 10 citations

FORMATION OF β-GLOBIN FOLLOWING INFECTION WITH RECOMBINANTS CONTAINING RABBIT β-GLOBIN cDNA AT DIFFERENT LOCATIONS OF SV40's LATE REGION

1980 • 5 citations