Cerebrovascular permeability to peptides: manipulations of transport systems at the blood-brain barrier.

An in situ brain perfusion technique to study cerebrovascular transport in the rat

1984 • 538 citations

Capillary Depletion Method for Quantification of Blood–Brain Barrier Transport of Circulating Peptides and Plasma Proteins

1990 • 454 citations

Blood-brain barrier transcytosis of insulin in developing rabbits

1987 • 348 citations

Macromolecular permeability across the blood-nerve and blood-brain barriers.

1994 • 343 citations

Blood-Brain Barrier Penetration and in Vivo Activity of an NGF Conjugate

1993 • 316 citations

Peptide Drug Delivery to the Brain

1992 • 309 citations

CNS effects of peripherally administered brain peptides

1979 • 278 citations

Comparison of in vitro and in vivo models of drug transcytosis through the blood-brain barrier.

1990 • 263 citations

Entry of Opioid Peptides into the Central Nervous System

1980 • 247 citations

Recent Advances in Blood-Brain Barrier Transport

1988 • 230 citations

Blood-Brain Barrier Restriction of Peptides and the Low Uptake of Enkephalins*

1978 • 225 citations

Rapid appearance of intraventricularly administered neuropeptides in the peripheral circulation

1982 • 224 citations

Characterization of Apolipoprotein J-Alzheimer's Aβ Interaction

1995 • 194 citations

Transcytotic pathway for blood-borne protein through the blood-brain barrier.

1988 • 188 citations

Blood—Brain Barrier and Peptides

1985 • 186 citations

Blood-Brain Barrier Transport of Circulating Alzheimer′s Amyloid β

1993 • 170 citations

Evidence for carrier-mediated transport of glutathione across the blood-brain barrier in the rat.

1990 • 163 citations

Pharmacologic effects in vivo in brain by vector-mediated peptide drug delivery.

1993 • 153 citations

Measurement of Solute Transport Across the Blood–Brain Barrier in the Perfused Guinea Pig Brain: Method and Application to N‐Methyl‐α‐Aminoisobutyric Acid

1986 • 152 citations

The Soluble Form of Alzheimer′s Amyloid β Protein Is Complexed to High Density Lipoprotein 3 and Very High Density Lipoprotein in Normal Human Plasma

1994 • 139 citations

Brain Uptake of Circulating Apolipoproteins J and E Complexed to Alzheimer′s Amyloid β

1994 • 133 citations

Permeability of the Blood‐Brain Barrier to the Immunosuppressive Cyclic Peptide Cyclosporin A

1990 • 128 citations

Transport of Leucine‐Enkephalin Across the Blood‐Brain Barrier in the Perfused Guinea Pig Brain

1987 • 120 citations

Plasma protein-mediated transport of steroid and thyroid hormones

1987 • 119 citations

Differential expression of Na,K-ATPase alpha and beta subunit isoforms at the blood-brain barrier and the choroid plexus.

1993 • 114 citations

Blood-brain barrier permeability to leucine-enkephalin,d-Alanine2-d-leucine5-enkephalin and their N-terminal amino acid (tyrosine)

1985 • 112 citations

Enkephalin and Blood-Brain Barrier: Studies of Binding and Degradation in Isolated Brain Micro vessels*

1981 • 106 citations

Carrier‐mediated transport of vasorpressin across the blood‐brain barrier of the mouse

1987 • 102 citations

Central Regulation of Intestinal Motility by Somatostatin and Cholecystokinin Octapeptide

1982 • 98 citations

Kinetics of arginine-vasopressin uptake at the blood-brain barrier

1990 • 98 citations

Blood-brain barrier, half-time disappearance, and brain distribution for labeled enkephalin and a potent analog

1976 • 94 citations

Permeability of the blood-cerebrospinal fluid and blood-brain barriers to thyrotropin-releasing hormone

1985 • 93 citations

Slow Penetration of Thyrotropin‐Releasing Hormone Across the Blood‐Brain Barrier of an In Situ Perfused Guinea Pig Brain

1988 • 89 citations

Blood-brain barrier permeability to peptides: Pitfalls in measurement

1981 • 88 citations

Kinetic Analysis of Leucine-Enkephalin Cellular Uptake at the Luminal Side of the Blood-Brain Barrier of an In Situ Perfused Guinea-Pig Brain

1989 • 86 citations

βEndorphin Chimeric Peptides: Transport through the Blood-Brain Barrierin Vivoand Cleavage of Bisulfide Linkage by Brain*

1990 • 67 citations

A saturable mechanism for transport of immunoglobulin G across the blood-brain barrier of the guinea pig

1990 • 67 citations

Blood-brain barrier transport of neuropeptides: analysis with a metabolically stable dermorphin analogue

1994 • 65 citations

Evidence for Transcapillary Transport of Reduced Glutathione in Vascular Perfused Guinea-Pig Brain

1994 • 63 citations

Unifying features of systemic and cerebral amyloidosis

1994 • 62 citations

Low permeability of the blood-brain barrier to nanomolar concentrations of immunoreactive alpha-melanotropin

1988 • 62 citations

Aluminum alters the permeability of the blood-brain barrier to some non-peptides

1985 • 61 citations

Use of neutral avidin improves pharmacokinetics and brain delivery of biotin bound to an avidin-monoclonal antibody conjugate.

1994 • 57 citations

Central nervous system effects of peptides, 1980–1985: A cross-listing of peptides and their central actions from the first six years of the journal Peptides

1986 • 56 citations

Delivering peptides to the central nervous system: dilemmas and strategies.

1991 • 54 citations

Transport of glutathione at blood-brain barrier of the rat: inhibition by glutathione analogs and age-dependence.

1992 • 49 citations

Expression cloning of a rat hepatic reduced glutathione transporter with canalicular characteristics.

1994 • 49 citations

The Blood-Brain Barrier, Amino Acids and Peptides

1989 • 47 citations

Radioactively iodinated cyclo(His-Pro) crosses the blood-brain barrier and reverses ethanol-induced narcosis

1993 • 45 citations

Receptor-mediated Transport of Therapeutics across the Blood-Brain Barrier

1994 • 45 citations

Transport, uptake, and metabolism of blood-borne vasopressin by the blood-brain barrier

1992 • 45 citations

Some Relationships Between Addiction and Drug Delivery to the Brain

1992 • 44 citations

Adamantane as a brain-directed drug carrier for poorly absorbed drug: Antinociceptive effects of [D-Ala2] Leu-enkephalin derivatives conjugated with the 1-adamantane moiety

1991 • 39 citations

Blood-brain barrier permeability to dipeptides and their constituent amino acids

1983 • 39 citations

Clearance of Vasopressin from Cerebrospinal Fluid to Blood in Chronically Cannulated Brattleboro Rats

1983 • 35 citations

Saturable efflux of the peptides RC-160 and Tyr-MIF-1 by different parts of the blood-brain barrier

1994 • 33 citations

Saturable mechanism for delta sleep-inducing peptide (DSIP) at the blood-brain barrier of the vascularly perfused guinea pig brain

1989 • 31 citations

Unidirectional uptake of enkephalins at the blood-tissue interface of the blood-cerebrospinal fluid barrier: a saturable mechanism

1988 • 30 citations

Passage of delta sleep-inducing peptide (DSIP) across the blood-cerebrospinal fluid barrier

1988 • 29 citations

Kinetics of circulating vasopressin uptake by choroid plexus

1991 • 23 citations

In vivo approaches for studying peptide interactions at the blood — brain barrier

1990 • 21 citations

CBG does not restrict blood-brain barrier corticosterone transport in rabbits

1986 • 13 citations

Neuroactive Peptides and Amino Acids at the Blood-Brain Barrier: Possible Implications for Drug Abuse

1992 • 12 citations

Vasopressin uptake by hypothalamopituitary axis and pineal gland in guinea pigs

1991 • 8 citations

Deleted Work

1955 • 0 citations