Effect of Endothelin-A Receptor Blockade With Atrasentan on Tumor Progression in Men With Hormone-Refractory Prostate Cancer: A Randomized, Phase II, Placebo-Controlled Trial

The European Organization for Research and Treatment of Cancer QLQ-C30: A Quality-of-Life Instrument for Use in International Clinical Trials in Oncology

1993 • 14,121 citations

SF-36 health survey: Manual and interpretation guide

2003 • 11,679 citations

Toxicity and response criteria of the Eastern Cooperative Oncology Group

1982 • 10,605 citations

Cancer Statistics, 2001

2001 • 3,342 citations

Chemotherapy with mitoxantrone plus prednisone or prednisone alone for symptomatic hormone-resistant prostate cancer: a Canadian randomized trial with palliative end points.

1996 • 1,584 citations

STUDIES ON PROSTATIC CANCER

1941 • 1,498 citations

Eligibility and Response Guidelines for Phase II Clinical Trials in Androgen-Independent Prostate Cancer: Recommendations From the Prostate-Specific Antigen Working Group

1999 • 994 citations

Hydrocortisone With or Without Mitoxantrone in Men With Hormone-Refractory Prostate Cancer: Results of the Cancer and Leukemia Group B 9182 Study

1999 • 907 citations

Endothelins

1995 • 682 citations

Measuring quality of life in men with prostate cancer using the Functional Assessment of Cancer Therapy-prostate instrument

1997 • 657 citations

Identification of endothelin–1 in the pathophysiology of metastatic adenocarcinoma of the prostate

1995 • 627 citations

Endothelin-1 production and decreased endothelin B receptor expression in advanced prostate cancer.

1996 • 330 citations

Phase II Study of Docetaxel, Estramustine, and Low-Dose Hydrocortisone in Men With Hormone-Refractory Prostate Cancer: A Final Report of CALGB 9780

2001 • 327 citations

Phase I Trial of Docetaxel With Estramustine in Androgen-Independent Prostate Cancer

1999 • 318 citations

Phase II trial of 96-hour paclitaxel plus oral estramustine phosphate in metastatic hormone-refractory prostate cancer.

1997 • 274 citations

Pharmacological characterization of A-127722: an orally active and highly potent ETA-selective receptor antagonist.

1996 • 207 citations

Expression of endothelin 1 and endothelin A receptor in ovarian carcinoma: evidence for an autocrine role in tumor growth.

1999 • 205 citations

New bone formation in an osteoblastic tumor model is increased by endothelin-1 overexpression and decreased by endothelin A receptor blockade

1999 • 169 citations

Behavioral signs of acute pain produced by application of endothelin-1 to rat sciatic nerve

1998 • 147 citations

The effects of the endothelin family peptides on cultured osteoblastic cells from rat calvariae

1990 • 131 citations

Clinical Trials in Relapsed Prostate Cancer: Defining the Target

1996 • 129 citations

Endothelin-1 in the Human Prostate: Tissue Levels, Source of Production and Isometric Tension Studies

1993 • 120 citations

EXPRESSION OF ENDOTHELIN RECEPTOR A ASSOCIATED WITH PROSTATE CANCER PROGRESSION

2001 • 116 citations

Endothelin-1 from prostate cancer cells is enhanced by bone contact which blocks osteoclastic bone resorption

2000 • 115 citations

Correlation of Endothelin-1 and Transforming Growth Factor β1 with Malignancy and Vascularity in Human Gliomas

1997 • 109 citations

Orchiectomy versus goserelin and flutamide in the treatment of newly diagnosed metastatic prostate cancer. Analysis of the criteria of evaluation used in the european organization for research and treatment of cancer–-genitourinary group study 30853

1993 • 86 citations

Endothelin messenger RNA and receptors are differentially expressed in cultured human breast epithelial and stromal cells.

1990 • 81 citations

Expression and localization of endothelin-1 and endothelin receptors in human meningiomas. Evidence for a role in tumoral growth.

1995 • 79 citations

Methylation of the neutral endopeptidase gene promoter in human prostate cancers.

2000 • 79 citations

Economic evaluation of chemotherapy with mitoxantrone plus prednisone for symptomatic hormone-resistant prostate cancer: based on a Canadian randomized trial with palliative end points.

1998 • 78 citations

Cost-Utility Analysis of Chemotherapy Using Paclitaxel, Docetaxel, or Vinorelbine for Patients With Anthracycline-Resistant Breast Cancer

1999 • 61 citations

Expression of endothelin 1 and endothelin A receptor in HPV‐associated cervical carcinoma: new potential targets for anticancer therapy

2000 • 57 citations

Abundant expression of immunoreactive endothelin 1 in mammary phyllodes tumor: possible paracrine role of endothelin 1 in the growth of stromal cells in phyllodes tumor.

1992 • 41 citations

Paracrine regulation of ovarian cancer by endothelin

1999 • 35 citations

The Role of the Endothelin Axis in Prostate Cancer

1999 • 13 citations

Multiple-Dose Pharmacokinetics of Atrasentan, an Endothelin-A Receptor Antagonist

2001 • 13 citations