Endothelin-1 from prostate cancer cells is enhanced by bone contact which blocks osteoclastic bone resorption

LNCaP model of human prostatic carcinoma.

1983 • 1,749 citations

Identification of endothelin–1 in the pathophysiology of metastatic adenocarcinoma of the prostate

1995 • 627 citations

Resorption of bone by isolated rabbit osteoclasts

1984 • 423 citations

Resorption of dentine by isolated osteoclasts in vitro

1984 • 296 citations

Histomorphometric analysis of sclerotic bone metastases from prostatic carcinoma with special reference to osteomalacia

1983 • 207 citations

Expression of endothelin 1 and endothelin A receptor in ovarian carcinoma: evidence for an autocrine role in tumor growth.

1999 • 205 citations

Design and Testing of β-Actin Primers for RT-PCR that Do Not Co-amplify Processed Pseudogenes

1997 • 182 citations

An amino-terminal fragment of urokinase isolated from a prostate cancer cell line (PC-3) is mitogenic for osteoblast-like cells

1990 • 177 citations

New bone formation in an osteoblastic tumor model is increased by endothelin-1 overexpression and decreased by endothelin A receptor blockade

1999 • 169 citations

Endothelin inhibits osteoclastic bone resorption by a direct effect on cell motility: implications for the vascular control of bone resorption.

1992 • 122 citations

Characteristics of prostate-derived growth factors for cells of the osteoblast phenotype.

1987 • 107 citations

Biological activity of chicken calcitonin: Effects on neonatal rat and embryonic chick osteoclasts

1987 • 75 citations

Massive amounts of immunoreactive endothelin in human seminal fluid.

1992 • 58 citations

Endothelin modulates osteopontin and osteocalcin messenger ribonucleic acid expression in rat osteoblastic osteosarcoma cells

1993 • 58 citations

Establishment of new human prostatic cancer cell line (JCA-I)

1990 • 49 citations

Massive amounts of immunoreactive endothelin in human seminal fluid

1992 • 40 citations

Prostate-derived soluble factors block osteoblast differentiation in culture

1996 • 29 citations

Involvement of prostate specific antigen in the stimulation of LNCaP cell growth

1996 • 9 citations

Antiproliferative Effect of a Prostatic Cell-Derived Activity on the Human Androgen-Dependent Prostatic Carcinoma Cell Line LNCaP

1995 • 6 citations

Soluble factors produced by PC-3 prostate cells decrease collagen content and mineralisation rate in fetal rat osteoblasts in culture

1996 • 5 citations

Detection of an inhibiting activity for osteoclast bone resorption from human prostatic cancer cells

1998 • 2 citations