Peroxynitrite Mediated Oxidation of Purine Bases of Nucleosides and Isolated DNA

Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide.

1990 • 7,068 citations

Biochemistry of Nitric Oxide and Its Redox-Activated Forms

1992 • 2,725 citations

A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds

1993 • 2,423 citations

Peroxynitrite-induced membrane lipid peroxidation: The cytotoxic potential of superoxide and nitric oxide

1991 • 2,215 citations

Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide dismutase

1992 • 1,499 citations

Nitric oxide regulation of superoxide and peroxynitrite-dependent lipid peroxidation. Formation of novel nitrogen-containing oxidized lipid derivatives

1994 • 1,348 citations

Peroxynitrite, a cloaked oxidant formed by nitric oxide and superoxide

1992 • 1,319 citations

Oxidants in Cigarette Smoke Radicals, Hydrogen Peroxide, Peroxynitrate, and Peroxynitritea

1993 • 1,142 citations

Peroxynitrite formation from macrophage-derived nitric oxide

1992 • 1,118 citations

Hydroxylation of deoxyguanosine at the C-8 position by ascorbic acid and other reducing agents

1984 • 941 citations

Kinetics of superoxide dismutase- and iron-catalyzed nitration of phenolics by peroxynitrite

1992 • 758 citations

A radical hypothesis for neurodegeneration

1993 • 727 citations

Superoxide and peroxynitrite inatherosclerosis.

1994 • 674 citations

Hydroxyl Free Radical Adduct of Deoxyguanosine: Sensitive Detection and Mechanisms of Formation

1986 • 660 citations

Reaction of superoxide with nitric oxide to form peroxonitrite in alkaline aqueous solution

1985 • 512 citations

Kinetics of nitric oxide and hydrogen peroxide production and formation of peroxynitrite during the respiratory burst of human neutrophils

1994 • 369 citations

The chemistry of pernitrites. Part I. Kinetics of decomposition of pernitrous acid

1968 • 348 citations

2,2-Diamino-4-[(3,5-di-O-acetyl-2-deoxy-.beta.-D-erythro- pentofuranosyl)amino]-5-(2H)-oxazolone: a Novel and Predominant Radical Oxidation Product of 3',5'-Di-O-acetyl-2'-deoxyguanosine

1994 • 337 citations

One- and two-electron oxidations of methionine by peroxynitrite.

1994 • 318 citations

Photosensitized formation of 7,8-dihydro-8-oxo-2'-deoxyguanosine (8-hydroxy-2'-deoxyguanosine) in DNA by riboflavin: a nonsinglet oxygen-mediated reaction

1992 • 295 citations

The Comparative Toxicity of Nitric Oxide and Peroxynitrite to Escherichia coli

1995 • 286 citations

Nitric Oxide Induces Oxidative Damage in Addition to Deamination in Macrophage DNA

1995 • 258 citations

Inactivation of .alpha.1-proteinase inhibitor by peroxynitrite

1992 • 253 citations

A stable solid that generates hydroxyl radical upon dissolution in aqueous solutions: reaction with proteins and nucleic acid

1992 • 229 citations

Formation of 8-hydroxyguanine moiety in deoxyribonucleic acid on .gamma.-irradiation in aqueous solution

1985 • 224 citations

On the pH-dependent yield of hydroxyl radical products from peroxynitrite

1994 • 202 citations

Radiation-induced Decomposition of the Purine Bases within DNA and Related Model Compounds

1985 • 193 citations

Peroxynitrite Causes DNA Nicks in Plasmid pBR322

1995 • 185 citations

Photosensitized reactions of nucleic acids

1986 • 180 citations

Reaction of Singlet Oxygen with 2'-Deoxyguanosine and DNA. Isolation and Characterization of the Main Oxidation Products

1995 • 179 citations

Spin-Trapping Studies of Peroxynitrite Decomposition and of 3-Morpholinosydnonimine N-Ethylcarbamide Autooxidation: Direct Evidence for Metal-Independent Formation of Free-Radical Intermediates

1994 • 171 citations

Singlet molecular oxygen production in the reaction of peroxynitrite with hydrogen peroxide

1994 • 159 citations

Mechanisms and Products of Photosensitized Degradation of Nucleic Acids and Related Model Compounds

1983 • 139 citations

Kinetics of N-Nitrosation in Oxygenated Nitric Oxide Solutions at Physiological pH: Role of Nitrous Anhydride and Effects of Phosphate and Chloride

1995 • 121 citations

Role of Conformation of Peroxynitrite Anion (ONOO-) with Its Stability and Toxicity

1994 • 118 citations

Peroxynitrite and atherosclerosis

1993 • 99 citations

Induction of mutations and chromosome aberrations in lung cells following in vivo exposure of rats to nitrogen oxides

1984 • 98 citations

PHTHALOCYANINE AND NAPHTHALOCYANINE PHOTOSENSITIZED OXIDATION OF 2′‐DEOXYGUANOSINE

1992 • 93 citations

8-Substituted guanosine and 2'-deoxyguanosine derivatives as potential inducers of the differentiation of Friend erythroleukemia cells

1985 • 89 citations

Evidence for the formation of hydroxyl radicals in the isomerization of pernitrous acid to nitric acid in aqueous solution

1970 • 88 citations

Free radical yields from the homolysis of peroxynitrous acid

1992 • 86 citations

Does peroxynitrite generate hydroxyl radical?

1995 • 75 citations

[8] Singlet oxygen DNA damage: Chromatographic and mass spectrometric analysis of damage products

1994 • 70 citations

High Performance Liquid Chromatography-Electrochemical Assay for Monitoring the Formation of 8-Oxo-7,8-dihydroadenine and its Related 2′-Deoxyribonucleoside

1990 • 54 citations

PHTHALOCYANINE AND NAPHTHALOCYANINE PHOTOSENSITIZED OXIDATION OF 2′‐DEOXYGUANOSINE: DISTINCT TYPE I AND TYPE II PRODUCTS

1984 • 30 citations

Water Radiolysis Products and Nucleotide Damage in γ-irradiated DNA

1981 • 23 citations

Water Radiolysis Products and Nucleotide Damage in γ-irradiated DNA

1981 • 12 citations