Transgenic expression of interleukin 7 restores T cell populations in nude mice.

Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice.

1994 • 1,572 citations

Stimulation of B-cell progenitors by cloned murine interleukin-7

1988 • 826 citations

Negative selection of lymphocytes

1994 • 810 citations

New member of the winged-helix protein family disrupted in mouse and rat nude mutations

1994 • 651 citations

Positive selection of lymphocytes

1994 • 563 citations

Continuous proliferation of murine antigen-specific helper T lymphocytes in culture.

1979 • 522 citations

Expression and function of the interleukin 7 receptor in murine lymphocytes.

1993 • 496 citations

Inhibition of murine B and T lymphopoiesis in vivo by an anti-interleukin 7 monoclonal antibody.

1993 • 345 citations

Cutaneous lymphoproliferation and lymphomas in interleukin 7 transgenic mice.

1993 • 255 citations

T-Cell Differentiation is Influenced by Thymic Microenvironments

1991 • 239 citations

Recombinant interleukin 7, pre-B cell growth factor, has costimulatory activity on purified mature T cells.

1989 • 230 citations

Interleukin-7: a Cofactor For V(D)J Rearrangement of the T Cell Receptor β Gene

1993 • 221 citations

Interleukin 7 is a T-cell growth factor.

1989 • 206 citations

Interleukin 7 is produced by murine and human keratinocytes.

1993 • 198 citations

IL-7 is a growth and maintenance factor for mature and immature thymocyte subsets

1989 • 180 citations

Effect of IL-7 on the growth of fetal thymocytes in culture.

1989 • 179 citations

Analysis of cytokine gene expression during fetal thymic ontogeny using the polymerase chain reaction.

1991 • 175 citations

Monoclonal antibodies to murine CD3 epsilon define distinct epitopes, one of which may interact with CD4 during T cell activation.

1989 • 159 citations

Murine thymocytes proliferate in direct response to interleukin-7

1989 • 157 citations

The lymphoid tissues in mice with congenital aplasia of the thymus.

1969 • 155 citations

IL-7 promotes thymocyte proliferation and maintains immunocompetent thymocytes bearing alpha beta or gamma delta T-cell receptors in vitro: synergism with IL-2.

1989 • 119 citations

Administration of IL-7 to normal mice stimulates B-lymphopoiesis and peripheral lymphadenopathy.

1991 • 117 citations

Interleukin‐7 expression during mouse thymus development

1992 • 112 citations

IL-7 maintains the T cell precursor potential of CD3-CD4-CD8- thymocytes.

1991 • 100 citations

Thymic Requirement for Clonal Deletion During T Cell Development

1989 • 95 citations

Administration of IL-7 to mice with cyclophosphamide-induced lymphopenia accelerates lymphocyte repopulation.

1991 • 88 citations

Extrathymic T cell maturation. Phenotypic analysis of T cell subsets in nude mice as a function of age.

1992 • 79 citations

Failure of T Cell Receptor V _β Negative Selection in an Athymic Environment

1989 • 76 citations

Interleukin 7-induced expression of specific T cell receptor gamma variable region genes in murine fetal liver cultures.

1993 • 69 citations

Constitutive Expression of Interleukin-7 mRNA and Production of IL-7 by a Cloned Murine Thymic Stromal Cell Line

1990 • 68 citations

Interleukin 7 (murine pre‐B cell growth factor/lymphopoietin 1) stimulates thymocyte growth: regulation by transforming growth factor beta

1989 • 66 citations

Thymic epithelium and the induction of transplantation tolerance in nude mice

1985 • 64 citations

Heterogeneity of thymic epithelial cells in promoting T-lymphocyte differentiation in vivo.

1991 • 56 citations

Extrathymic Pathways of T‐Cell Differentiation: A Primitive and Fundamental Immune System

1993 • 54 citations

T cell antigen receptor phosphorylation induced by an anti-receptor antibody.

1987 • 53 citations

Extrathymic positive selection of αβ T-cell precursors in nude mice

1992 • 36 citations

Thymus‐derived cytokine(s) including interleukin‐7 induce increase of T cell receptor α/β⁺ CD4⁻CD8⁻ T cells which are extrathymically differentiated in athymic nude mice

1993 • 36 citations

Interleukin 7 preferentially supports the growth of γδ T cell receptor-bearing T cells from fetal thymocytes in vitro

1991 • 35 citations

Murine thymocytes proliferate in direct response to interleukin-7

1989 • 20 citations

Alterations in lymphopoiesis after hematopoietic reconstitution with IL-7 virus-infected bone marrow.

1993 • 19 citations

New member of the winged-helix protein family disrupted in mouse and rat nude mutations

1995 • 15 citations

Dual role of IL-7 in the growth and differentiation of immature thymocytes.

1992 • 12 citations