Cannabinoids Enhance Subsecond Dopamine Release in the Nucleus Accumbens of Awake Rats

Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats.

1988 • 4,617 citations

Predictive Reward Signal of Dopamine Neurons

1998 • 4,446 citations

Role of Endogenous Cannabinoids in Synaptic Signaling

2003 • 1,535 citations

The role of nucleus accumbens dopamine in motivated behavior: a unifying interpretation with special reference to reward-seeking

1999 • 1,420 citations

Endocannabinoid Signaling in the Brain

2002 • 1,240 citations

Subsecond dopamine release promotes cocaine seeking

2003 • 1,086 citations

Cannabinoid and Heroin Activation of Mesolimbic Dopamine Transmission by a Common µ ₁ Opioid Receptor Mechanism

1997 • 1,078 citations

Brain Reward Circuitry

2002 • 875 citations

Low doses of ethanol activate dopaminergic neurons in the ventral tegmental area

1985 • 788 citations

Dopamine Operates as a Subsecond Modulator of Food Seeking

2004 • 686 citations

Modulation of transmitter release via presynaptic cannabinoid receptors

2001 • 670 citations

Nonlinear relationship between impulse flow and dopamine released by rat midbrain dopaminergic neurons as studied by in vivo electrochemistry

1988 • 663 citations

Firing modes of midbrain dopamine cells in the freely moving rat

2002 • 494 citations

Burst firing in midbrain dopaminergic neurons

1997 • 482 citations

Endocannabinoids Mediate Presynaptic Inhibition of Glutamatergic Transmission in Rat Ventral Tegmental Area Dopamine Neurons through Activation of CB1 Receptors

2004 • 466 citations

Real-time characterization of dopamine overflow and uptake in the rat striatum

1988 • 420 citations

Cannabinoids excite dopamine neurons in the ventral tegmentum and substantia nigra

1997 • 366 citations

Overoxidation of carbon-fiber microelectrodes enhances dopamine adsorption and increases sensitivityElectronic supplementary information (ESI) available: National Instruments Data Acquisition System. See http://www.rsc.org/suppdata/an/b3/b307024g/

2003 • 364 citations

Cannabinoids activate mesolimbic dopamine neurons by an action on cannabinoid CB1 receptors

1998 • 363 citations

Dissociation of dopamine release in the nucleus accumbens from intracranial self-stimulation

1999 • 326 citations

Regulation of dopamine release by impulse flow and by autoreceptors as studied by in vivo voltammetry in the rat striatum

1985 • 317 citations

Frequency of Dopamine Concentration Transients Increases in Dorsal and Ventral Striatum of Male Rats during Introduction of Conspecifics

2002 • 279 citations

Real‐time decoding of dopamine concentration changes in the caudate–putamen during tonic and phasic firing

2003 • 276 citations

Cannabinoids: reward, dependence, and underlying neurochemical mechanisms?a review of recent preclinical data

2003 • 275 citations

SHORT COMMUNICATION Inhibition of GABAergic neurotransmission in the ventral tegmental area by cannabinoids

2002 • 265 citations

Δ9-Tetrahydrocannabinol excites rat VTA dopamine neurons through activation of cannabinoid CB1 but not opioid receptors

1997 • 227 citations

The absolute configuration of δ1-tetrahydrocannabinol, the major active constituent of hashish.

1967 • 214 citations

Activational role of cannabinoids on movement

2000 • 205 citations

Real‐Time Measurement of Electrically Evoked Extracellular Dopamine in the Striatum of Freely Moving Rats

1997 • 192 citations

Dynamic Gain Control of Dopamine Delivery in Freely Moving Animals

2004 • 177 citations

Correlation of local changes in extracellular oxygen and pH that accompany dopaminergic terminal activity in the rat caudate–putamen

2003 • 156 citations

Endogenous cannabinoids as an aversive or counter-rewarding system in the rat

1997 • 152 citations

Cannabinoid receptors and reward in the rat: a conditioned place preference study

2000 • 144 citations

Addictive potential of cannabinoids: the underlying neurobiology

2002 • 136 citations

Cannabinoid pharmacological properties common to other centrally acting drugs

2003 • 134 citations

Strain-specific facilitation of dopamine efflux by Δ9-tetrahydrocannabinol in the nucleus accumbens of rat: An in vivo microdialysis study

1991 • 133 citations

Increase in meso-prefrontal dopaminergic activity after stimulation of CB1 receptors by cannabinoids

1998 • 130 citations

Effects of Cannabinoids on Dopamine Release in the Corpus Striatum and the Nucleus Accumbens In Vitro

1999 • 121 citations

From neurobiology to treatment: progress against addiction

2002 • 118 citations

Effects of chronic Δ9-tetrahydrocannabinol on rat midbrain dopamine neurons: an electrophysiological assessment

2000 • 114 citations

Critical guidelines for validation of the selectivity of in-vivo chemical microsensors

2003 • 113 citations

Effect of acute ethanol on striatal dopamine neurotransmission in ambulatory rats.

2001 • 104 citations

CB1 cannabinoid receptor agonist WIN 55, 212-2 decreases intravenous cocaine self-administration in rats

1999 • 100 citations

Dependence of mesolimbic dopamine transmission on Δ9-tetrahydrocannabinol

1999 • 89 citations

Improving Data Acquisition for Fast-Scan Cyclic Voltammetry

1999 • 88 citations

Lack of response suppression follows repeated ventral tegmental cannabinoid administration: an in vitro electrophysiological study

2000 • 73 citations

Stereochemistry of the π-route to 2,4-disubstituted adamantanes

1971 • 67 citations

Differential cannabinoid-induced electrophysiological effects in rat ventral tegmentum

2003 • 59 citations

Cannabinoid CB1 receptors colocalize with tyrosine hydroxylase in cultured fetal mesencephalic neurons and their activation increases the levels of this enzyme

2000 • 58 citations

Clozapine-Induced Increase in Plasma Levels of Soluble Interleukin-2 Receptors-Reply

1995 • 19 citations