The zta transactivator involved in induction of lytic cycle gene expression in Epstein-Barr virus-infected lymphocytes binds to both AP-1 and ZRE sites in target promoter and enhancer regions

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

The Steroid and Thyroid Hormone Receptor Superfamily

1988 • 7,590 citations

The Leucine Zipper: A Hypothetical Structure Common to a New Class of DNA Binding Proteins

1988 • 3,479 citations

Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor

1987 • 3,057 citations

Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements

1987 • 2,107 citations

Fos and jun: The AP-1 connection

1988 • 1,597 citations

Human Proto-Oncogene c- jun Encodes a DNA Binding Protein with Structural and Functional Properties of Transcription Factor AP-1

1987 • 1,353 citations

The c-fos protein interacts with c-JunAP-1 to stimulate transcription of AP-1 responsive genes

1988 • 1,352 citations

Elution of proteins from sodium dodecyl sulfate-polyacrylamide gels, removal of sodium dodecyl sulfate, and renaturation of enzymatic activity: Results with sigma subunit of Escherichia coli RNA polymerase, wheat germ DNA topoisomerase, and other enzymes

1980 • 1,256 citations

The jun proto-oncogene is positively autoregulated by its product, Jun/AP-1

1988 • 1,256 citations

Cloning and structural analysis of cDNAs for bcl-2 and a hybrid bcl-2/immunoglobulin transcript resulting from the t(14;18) translocation

1986 • 1,232 citations

c-Jun dimerizes with itself and with c-Fos, forming complexes of different DNA binding affinities

1988 • 1,084 citations

Isolation of a recombinant copy of the gene encoding C/EBP.

1988 • 1,003 citations

DNA binding activities of three murine Jun proteins: Stimulation by Fos

1988 • 850 citations

The role of the leucine zipper in the fos–jun interaction

1988 • 836 citations

Cyclic AMP-Responsive DNA-Binding Protein: Structure Based on a Cloned Placental cDNA

1988 • 772 citations

A gene activated by growth factors is related to the oncogene v-jun.

1988 • 771 citations

Activation of transcription by two factors that bind promoter and enhancer sequences of the human metallothionein gene and SV40

1987 • 762 citations

Fos-Associated Protein p39 Is the Product of the jun Proto-Oncogene

1988 • 643 citations

Persisting oncogenic herpesvirus induced by the tumour promoter TPA

1978 • 632 citations

Identification of a rat liver nuclear protein that binds to the enhancer core element of three animal viruses.

1987 • 631 citations

Identification of a cellular transcription factor involved in E1A trans-activation

1986 • 551 citations

fos-associated cellular p39 is related to nuclear transcription factor AP-1

1988 • 508 citations

Sequence-specific DNA binding of the Epstein-Barr virus nuclear antigen (EBNA-1) to clustered sites in the plasmid maintenance region

1985 • 502 citations

GCN4 protein, synthesize in vitro, binds HIS3 regulatory sequences: Implications for general control of amino acid biosynthetic genes in yeast

1985 • 496 citations

Direct interaction between fos and jun nuclear oncoproteins: role of the 'leucine zipper' domain

1988 • 455 citations

Activation of expression of latent Epstein-Barr herpesvirus after gene transfer with a small cloned subfragment of heterogeneous viral DNA.

1985 • 454 citations

Complete nucleotide sequence of a human c-onc gene: deduced amino acid sequence of the human c-fos protein.

1983 • 446 citations

Transactivation of a bovine papilloma virus transcriptional regulatory element by the E2 gene product

1985 • 402 citations

Identification and characterization of oriLyt, a lytic origin of DNA replication of Epstein-Barr virus

1988 • 386 citations

A herpesvirus trans-activating protein interacts with transcription factor OTF-1 and other cellular proteins.

1988 • 381 citations

Herpes simplex virus regulatory elements and the immunoglobulin octamer domain bind a common factor and are both targets for virion transactivation

1988 • 377 citations

trans activation of an Epstein-Barr viral transcriptional enhancer by the Epstein-Barr viral nuclear antigen 1.

1986 • 363 citations

A complex formed between cell components and an HSV structural polypeptide binds to a viral immediate early gene regulatory DNA sequence

1988 • 360 citations

Both Epstein-Barr virus (EBV)-encoded trans-acting factors, EB1 and EB2, are required to activate transcription from an EBV early promoter.

1986 • 359 citations

Epstein-Barr virus BZLF1 trans-activator specifically binds to a consensus AP-1 site and is related to c-fos.

1989 • 334 citations

Synchronous and sequential activation of latently infected Epstein-Barr virus genomes

1989 • 333 citations

Bovine papillomavirus E2 trans-activating gene product binds to specific sites in papillomavirus DNA

1987 • 330 citations

Use of a protein-blotting procedure and a specific DNA probe to identify nuclear proteins that recognize the promoter region of the transferrin receptor gene.

1985 • 290 citations

Functional domains of adenovirus type 5 E1a proteins

1987 • 283 citations

Homology between the DNA-binding domain of the GCN4 regulatory protein of yeast and the carboxyl-terminal region of a protein coded for by the oncogene jun.

1987 • 279 citations

trans activation of the latent Epstein-Barr virus (EBV) genome after transfection of the EBV DNA fragment

1986 • 278 citations

A new Epstein-Barr virus transactivator, R, induces expression of a cytoplasmic early antigen

1988 • 261 citations

The DNA-binding domains of the jun oncoprotein and the yeast GCN4 transcriptional activator protein are functionally homologous

1987 • 260 citations

A TATA box implicated in E1A transcriptional activation of a simple adenovirus 2 promoter

1987 • 227 citations

Activation of transcription factor IIIC by the adenovirus E1A protein

1988 • 197 citations

Identification of an Epstein-Barr virus early gene encoding a second component of the restricted early antigen complex

1987 • 183 citations

trans Activation of an Epstein-Barr Viral Transcriptional Enhancer by the Epstein-Barr Viral Nuclear Antigen 1

1986 • 176 citations

Epstein-Barr virus RNA. V. Viral RNA in a restringently infected, growth-transformed cell line

1980 • 175 citations

Structure and function of the adenovirus origin of replication

1984 • 163 citations

An enhancer within the divergent promoter of Epstein-Barr virus responds synergistically to the R and Z transactivators

1990 • 156 citations

Epstein-Barr virus gene expression in P3HR1-superinfected Raji cells

1987 • 142 citations

The Epstein-Barr virus (EBV) BZLF1 immediate-early gene product differentially affects latent versus productive EBV promoters

1989 • 141 citations

Promiscuous trans activation of gene expression by an Epstein-Barr virus-encoded early nuclear protein

1986 • 128 citations

Epstein-Barr virus with heterogeneous DNA disrupts latency

1984 • 128 citations

Overlapping octamer and TAATGARAT motifs in the VF65-response elements in herpes simplex virus immediate-early promoters represent independent binding sites for cellular nuclear factor III

1989 • 114 citations

Adenovirus E1a Gene Product Expressed at High Levels in Escherichia coli Is Functional

1984 • 111 citations

Organization of the Epstein-Barr virus DNA molecule. III. Location of the P3HR-1 deletion junction and characterization of the NotI repeat units that form part of the template for an abundant 12-O-tetradecanoylphorbol-13-acetate-induced mRNA transcript

1983 • 104 citations

The E2 "gene" of bovine papillomavirus encodes an enhancer-binding protein.

1987 • 98 citations

Responsiveness of the Epstein-Barr virus NotI repeat promoter to the Z transactivator is mediated in a cell-type-specific manner by two independent signal regions

1989 • 92 citations

The Epstein-Barr virus (EBV) DR enhancer contains two functionally different domains: domain A is constitutive and cell specific, domain B is transactivated by the EBV early protein R

1989 • 85 citations

Properties of a high-affinity DNA binding site for estrogen receptor.

1988 • 76 citations

Carboxyl-terminal domain of the Epstein-Barr virus nuclear antigen is highly immunogenic in man.

1985 • 58 citations

Structure and evolution of two related transcription units of Epstein-Barr virus carrying small tandem repeats

1985 • 55 citations

The Epstein-Barr virus (EBV) early promoter DR contains a cis-acting element responsive to the EBV transactivator EB1 and an enhancer with constitutive and inducible activities

1989 • 54 citations

Structure of defective DNA molecules in Epstein-Barr virus preparations from P3HR-1 cells

1984 • 49 citations

The palindromic series I repeats in the simian cytomegalovirus major immediate-early promoter behave as both strong basal enhancers and cyclic AMP response elements

1990 • 49 citations

Two distant clusters of partially homologous small repeats of Epstein-Barr virus are transcribed upon induction of an abortive or lytic cycle of the virus

1983 • 40 citations

TPA-inducible Epstein-Barr virus genes in Raji cells and their regulation

1988 • 40 citations