Angiopoietin-2 sensitizes endothelial cells to TNF-α and has a crucial role in the induction of inflammation

Angiopoietin-2, a Natural Antagonist for Tie2 That Disrupts in vivo Angiogenesis

1997 • 3,470 citations

Lymphocyte Homing and Homeostasis

1996 • 2,934 citations

Requisite Role of Angiopoietin-1, a Ligand for the TIE2 Receptor, during Embryonic Angiogenesis

1996 • 2,844 citations

Isolation of Angiopoietin-1, a Ligand for the TIE2 Receptor, by Secretion-Trap Expression Cloning

1996 • 1,969 citations

Leakage-Resistant Blood Vessels in Mice Transgenically Overexpressing Angiopoietin-1

1999 • 1,372 citations

Angiopoietin-1 protects the adult vasculature against plasma leakage

2000 • 1,271 citations

The role of angiogenesis in tumor growth.

1992 • 1,267 citations

Angiopoietin-2 Is Required for Postnatal Angiogenesis and Lymphatic Patterning, and Only the Latter Role Is Rescued by Angiopoietin-1

2002 • 993 citations

Heterogeneity of angiogenesis and blood vessel maturation in human tumors: implications for antiangiogenic tumor therapies.

2000 • 750 citations

The Tie-2 ligand Angiopoietin-2 is stored in and rapidly released upon stimulation from endothelial cell Weibel-Palade bodies

2004 • 695 citations

Endothelial proliferation in tumours and normal tissues: Continuous labelling studies

1984 • 562 citations

Angiopoietin-1 Is an Antipermeability and Anti-Inflammatory Agent In Vitro and Targets Cell Junctions

2000 • 496 citations

Cell Type-Specific Expression of Angiopoietin-1 and Angiopoietin-2 Suggests a Role in Glioblastoma Angiogenesis

1998 • 491 citations

Suppression of angiogenesis and tumor growth by selective inhibition of angiopoietin-2

2004 • 473 citations

Tie2 Expression and Phosphorylation in Angiogenic and Quiescent Adult Tissues

1997 • 410 citations

The Tie-2 ligand Angiopoietin-2 destabilizes quiescent endothelium through an internal autocrine loop mechanism

2005 • 367 citations

Tumor-derived vascular endothelial growth factor up-regulates angiopoietin-2 in host endothelium and destabilizes host vasculature, supporting angiogenesis in ovarian cancer.

2003 • 261 citations

Staphylococcus aureus extracellular adherence protein serves as anti-inflammatory factor by inhibiting the recruitment of host leukocytes

2002 • 257 citations

Clinical applications of TNF-α in cancer

1998 • 243 citations

Microtumor growth initiates angiogenic sprouting with simultaneous expression of VEGF, VEGF receptor-2, and angiopoietin-2

2002 • 222 citations

Microtumor growth initiates angiogenic sprouting with simultaneous expression of VEGF, VEGF receptor-2, and angiopoietin-2

2002 • 173 citations

Characterization of Angiogenesis and Microcirculation of High–Grade Glioma: An Intravital Multifluorescence Microscopic Approach in the Athymic Nude Mouse

1998 • 116 citations

Angiopoietin-1 Protects Against the Development of Cardiac Allograft Arteriosclerosis

2003 • 108 citations

Getting Tie(2)d up in angiogenesis

2002 • 69 citations

Dysmorphogenesis of Kidney Cortical Peritubular Capillaries in Angiopoietin-2-Deficient Mice

2004 • 55 citations

Intravital fluorescence microscopy for the study of leukocyte interaction with platelets and endothelial cells

1999 • 23 citations