Tie2 Expression and Phosphorylation in Angiogenic and Quiescent Adult Tissues

Patterns and Emerging Mechanisms of the Angiogenic Switch during Tumorigenesis

1996 • 6,878 citations

Requisite Role of Angiopoietin-1, a Ligand for the TIE2 Receptor, during Embryonic Angiogenesis

1996 • 2,844 citations

Angiogenesis.

1992 • 2,581 citations

Clinical Applications of Research on Angiogenesis

1995 • 2,300 citations

Isolation of Angiopoietin-1, a Ligand for the TIE2 Receptor, by Secretion-Trap Expression Cloning

1996 • 1,969 citations

Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation

1995 • 1,808 citations

Growth factor signaling by receptor tyrosine kinases

1992 • 1,450 citations

Receptor Protein-Tyrosine Kinases and Their Signal Transduction Pathways

1994 • 1,309 citations

Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryo.

1994 • 979 citations

Hypothesis: Vasa Vasorum and Neovascularization of Human Coronary Arteries

1984 • 852 citations

Vascular Dysmorphogenesis Caused by an Activating Mutation in the Receptor Tyrosine Kinase TIE2

1996 • 779 citations

Synergistic Effect of Vascular Endothelial Growth Factor and Basic Fibroblast Growth Factor on Angiogenesis In Vivo

1995 • 605 citations

Endothelial proliferation in tumours and normal tissues: Continuous labelling studies

1984 • 562 citations

Endothelial receptor tyrosine kinases involved in angiogenesis.

1995 • 537 citations

Salvage of Infarcted Myocardium by Angiogenic Action of Basic Fibroblast Growth Factor

1992 • 519 citations

Tie-1 and tie-2 define another class of putative receptor tyrosine kinase genes expressed in early embryonic vascular system.

1993 • 470 citations

Vascular endothelial growth factor receptor expression during embryogenesis and tissue repair suggests a role in endothelial differentiation and blood vessel growth.

1993 • 460 citations

tek, a novel tyrosine kinase gene located on mouse chromosome 4, is expressed in endothelial cells and their presumptive precursors.

1992 • 410 citations

The Wound Healing Process

1993 • 400 citations

Recombinant fibroblast growth factor-1 promotes intimal hyperplasia and angiogenesis in arteries in vivo

1993 • 367 citations

A novel endothelial cell surface receptor tyrosine kinase with extracellular epidermal growth factor homology domains.

1992 • 351 citations

Angiogenesis in female reproductive system

2001 • 338 citations

Enhanced angiogenesis and growth of collaterals by in vivo administration of recombinant basic fibroblast growth factor in a rabbit model of acute lower limb ischemia: Dose-response effect of basic fibroblast growth factor

1992 • 325 citations

Cell turnover of capillaries.

1967 • 294 citations

Expression of tie-2, a member of a novel family of receptor tyrosine kinases, in the endothelial cell lineage

1993 • 275 citations

Biology of Dermal Wound Repair

1993 • 266 citations

Effects of Chronic Systemic Administration of Basic Fibroblast Growth Factor on Collateral Development in the Canine Heart

1995 • 245 citations

Molecular Cloning and Characterization of Mouse TIE and TEK Receptor Tyrosine Kinase Genes and Their Expression in Hematopoietic Stem Cells

1993 • 224 citations

Phosphotyrosine phosphatases with SH2 domains: regulators of signal transduction

1994 • 182 citations

The GRB2/Sem‐5 adaptor protein

1994 • 182 citations

The endothelial-specific receptor tyrosine kinase, tek, is a member of a new subfamily of receptors.

1993 • 179 citations

Physiological assessment of augmented vascularity induced by VEGF in ischemic rabbit hindlimb

1994 • 156 citations

Cell autonomous functions of the receptor tyrosine kinase TIE in a late phase of angiogenic capillary growth and endothelial cell survival during murine development

1996 • 145 citations

Recovery of Disturbed Endothelium-Dependent Flow in the Collateral-Perfused Rabbit Ischemic Hindlimb After Administration of Vascular Endothelial Growth Factor

1995 • 145 citations

Distinct rat genes with related profiles of expression define a TIE receptor tyrosine kinase family.

1993 • 129 citations

Structure and function of SH2-domain containing tyrosine phosphatases

1993 • 118 citations

Maintenance of Vascular Endothelial Cell-Specific Properties after Immortalization with an Amphotrophic Replication-Deficient Retrovirus Containing Human Papilloma Virus 16 E6/E7 DNA

1995 • 110 citations

Molecular cloning and characterization of a novel receptor protein tyrosine kinase from human placenta.

1993 • 107 citations

Time Course of Cellular Proliferation, Intimal Hyperplasia, and Remodeling Following Angioplasty in Monkeys With Established Atherosclerosis

1996 • 102 citations

GRB2 and SH-PTP2: potentially important endothelial signaling molecules downstream of the TEK/TIE2 receptor tyrosine kinase.

1995 • 88 citations

Angiogenesis and the skin: A primer

1996 • 86 citations

Structure and function of vasa vasorum

1996 • 65 citations

Angiogenesis in atherosclerosis.

1992 • 63 citations

Stimulation of coronary collateral growth: Current developments in angiogenesis and future clinical applications

1992 • 40 citations

PDGF and FGF receptors in health and disease

1996 • 3 citations