Cbl promotes clustering of endocytic adaptor proteins

[20] Processing of X-ray diffraction data collected in oscillation mode

1997 • 33,348 citations

Coot: model-building tools for molecular graphics

2004 • 29,122 citations

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1998 • 15,791 citations

Refinement of Macromolecular Structures by the Maximum-Likelihood Method

1997 • 14,729 citations

Image processing with ImageJ

2004 • 11,866 citations

AMoRe: an automated package for molecular replacement

1994 • 4,990 citations

Rho GTPases in cell biology

2002 • 4,662 citations

Rapid measurement of binding constants and heats of binding using a new titration calorimeter

1989 • 2,603 citations

XtalView/Xfit—A Versatile Program for Manipulating Atomic Coordinates and Electron Density

1999 • 2,108 citations

Signals for Sorting of Transmembrane Proteins to Endosomes and Lysosomes

2003 • 1,999 citations

Main-chain Bond Lengths and Bond Angles in Protein Structures

1993 • 1,204 citations

Ligand-Induced, Receptor-Mediated Dimerization and Activation of EGF Receptor

2002 • 972 citations

Clathrin- and non-clathrin-mediated endocytic regulation of cell signalling

2005 • 852 citations

Clathrin-independent endocytosis of ubiquitinated cargos

2005 • 818 citations

Two Binding Orientations for Peptides to the Src SH3 Domain: Development of a General Model for SH3-Ligand Interactions

1994 • 800 citations

Multiple monoubiquitination of RTKs is sufficient for their endocytosis and degradation

2003 • 794 citations

SH3 domains: complexity in moderation

2001 • 778 citations

PAK Kinases Are Directly Coupled to the PIX Family of Nucleotide Exchange Factors

1998 • 745 citations

An approach to multi-copy search in molecular replacement

2000 • 700 citations

Cbl–CIN85–endophilin complex mediates ligand-induced downregulation of EGF receptors

2002 • 571 citations

MODULAR PEPTIDE RECOGNITION DOMAINS IN EUKARYOTIC SIGNALING

1997 • 558 citations

Structural determinants of peptide-binding orientation and of sequence specificity in SH3 domains

1994 • 519 citations

The endophilin–CIN85–Cbl complex mediates ligand-dependent downregulation of c-Met

2002 • 468 citations

ARP/wARP and molecular replacement

2001 • 465 citations

Distinct monoubiquitin signals in receptor endocytosis

2003 • 436 citations

Molecular Basis of Phosphorylation-Induced Activation of the NADPH Oxidase

2003 • 393 citations

The Structure and Function of Proline Recognition Domains

2003 • 358 citations

Endocytosis of Receptor Tyrosine Kinases Is Driven by Monoubiquitylation, Not Polyubiquitylation

2003 • 334 citations

Negative receptor signalling

2003 • 333 citations

A Novel Regulator of p21-activated Kinases

1998 • 313 citations

Activated Cdc42 Sequesters c-Cbl and Prevents EGF Receptor Degradation

2003 • 201 citations

Mechanisms controlling EGF receptor endocytosis and degradation

2003 • 169 citations

SH3 domains and drug design: Ligands, structure, and biological function

1997 • 164 citations

CIN85 Participates in Cbl-b-mediated Down-regulation of Receptor Tyrosine Kinases

2002 • 137 citations

Identification of a Novel Proline-Arginine Motif Involved in CIN85-dependent Clustering of Cbl and Down-regulation of Epidermal Growth Factor Receptors

2003 • 131 citations

CIN85 Associates with Multiple Effectors Controlling Intracellular Trafficking of Epidermal Growth Factor Receptors

2004 • 126 citations

How SH3 domains recognize proline

2002 • 109 citations

Characterization of the CIN85 Adaptor Protein and Identification of Components Involved in CIN85 Complexes

2000 • 80 citations

Atypical Recognition Consensus of CIN85/SETA/Ruk SH3 Domains Revealed by Target-assisted Iterative Screening

2003 • 69 citations

Leucine Zipper-mediated Homodimerization of the Adaptor Protein c-Cbl

1999 • 69 citations

Cargo- and compartment-selective endocytic scaffold proteins

2004 • 56 citations

The Cbl proteins are binding partners for the Cool/Pix family of p21‐activated kinase‐binding proteins

2003 • 39 citations