Rare occurrence of P53 gene mutations in multiple myeloma

Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction

1989 • 3,557 citations

Mutations in the p53 gene occur in diverse human tumour types

1989 • 2,765 citations

The p53 proto-oncogene can act as a suppressor of transformation

1989 • 2,019 citations

Generation of single-stranded DNA by the polymerase chain reaction and its application to direct sequencing of the HLA-DQA locus.

1988 • 1,582 citations

p53: A Frequent Target for Genetic Abnormalities in Lung Cancer

1989 • 1,214 citations

p53 mutations in human lymphoid malignancies: association with Burkitt lymphoma and chronic lymphocytic leukemia.

1991 • 915 citations

p53: oncogene or anti-oncogene?

1990 • 812 citations

Detection of p53 Gene Mutations in Human Brain Tumors by Single-strand Conformation Polymorphism Analysis of Polymerase Chain Reaction Products

1991 • 556 citations

Localization of gene for human p53 tumour antigen to band 17p13

1986 • 498 citations

Frequent Mutations in the p53 Tumor Suppressor Gene in Human Leukemia T-Cell Lines

1990 • 296 citations

Detection of ras gene mutations in human lung cancers by single-strand conformation polymorphism analysis of polymerase chain reaction products.

1990 • 213 citations

Loss of chromosome 17p13 sequences and mutation of p53 in human breast carcinomas.

1991 • 200 citations

Frequent mutations in the p53 tumor suppressor gene in human leukemia T-cell lines.

1990 • 195 citations

P53 gene mutations in acute myeloid leukemia with 17p monosomy

1991 • 184 citations

The spectrum of molecular alterations in the evolution of chronic myelocytic leukemia.

1991 • 171 citations

Mutations of the p53 gene in B-cell chronic lymphocytic leukemia: a report on 39 cases with cytogenetic analysis.

1992 • 147 citations

Rearrangement and expression of p53 in the chronic phase and blast crisis of chronic myelogenous leukemia

1990 • 138 citations

Mutations in the p53 gene in myelodysplastic syndromes.

1991 • 123 citations

Mutations of the P53 gene in acute myeloid leukaemia

1992 • 117 citations

Rearrangement and expression of p53 in the chronic phase and blast crisis of chronic myelogenous leukemia

1990 • 108 citations

Mutations of the p53 gene in lymphoid leukemia

1991 • 104 citations

Identification and characterization of a p53 gene mutation in a human osteosarcoma cell line.

1989 • 94 citations

Neoplastic Diseases of the Blood

1991 • 78 citations

Mutations of the p53 gene in B-cell lymphoblastic acute leukemia: a report on 60 cases.

1992 • 68 citations

P53 gene mutations in acute myeloid leukemia with 17p monosomy

1991 • 16 citations