Microtubules Remodel Actomyosin Networks in Xenopus Egg Extracts via Two Mechanisms of F-Actin Transport

Identification of a novel force-generating protein, kinesin, involved in microtubule-based motility

1985 • 1,930 citations

The Cell in Development and Heredity

1925 • 1,750 citations

Actin-Based Cell Motility and Cell Locomotion

1996 • 1,536 citations

ER-to-Golgi transport visualized in living cells

1997 • 1,169 citations

A Complex of NuMA and Cytoplasmic Dynein Is Essential for Mitotic Spindle Assembly

1996 • 565 citations

Cortical Flow in Animal Cells

1988 • 554 citations

Retrograde transport by the microtubule-associated protein MAP 1C

1987 • 547 citations

Force Generation by Microtubule Assembly/Disassembly in Mitosis and Related Movements

1995 • 531 citations

Localization of cytoplasmic dynein to mitotic spindles and kinetochores

1990 • 508 citations

Microtubule growth activates Rac1 to promote lamellipodial protrusion in fibroblasts

1999 • 491 citations

Functional cooperation between the microtubule and actin cytoskeletons

2000 • 473 citations

Actomyosin-based Retrograde Flow of Microtubules in the Lamella of Migrating Epithelial Cells Influences Microtubule Dynamic Instability and Turnover and Is Associated with Microtubule Breakage and Treadmilling

1997 • 470 citations

Microtubules Orient the Mitotic Spindle in Yeast through Dynein-dependent Interactions with the Cell Cortex

1997 • 468 citations

Cytoplasmic dynein and dynactin in cell division and intracellular transport

1999 • 454 citations

THE ROLE OF THREE CYTOPLASMIC FIBERS IN BHK-21 CELL MOTILITY

1971 • 453 citations

Microtubule Targeting of Substrate Contacts Promotes Their Relaxation and Dissociation

1999 • 452 citations

Real-time visualization of cell cycle-dependent changes in microtubule dynamics in cytoplasmic extracts

1990 • 444 citations

A model for the proposed roles of different microtubule-based motor proteins in establishing spindle bipolarity

1998 • 408 citations

Plectin sidearms mediate interaction of intermediate filaments with microtubules and other components of the cytoskeleton.

1996 • 406 citations

Cytokinesis in Animal Cells

1990 • 373 citations

Dynactin Is Required for Microtubule Anchoring at Centrosomes

1999 • 354 citations

Endoplasmic reticulum membrane tubules are distributed by microtubules in living cells using three distinct mechanisms

1998 • 351 citations

Evidence for actin filament-microtubule interaction mediated by microtubule-associated proteins

1978 • 346 citations

Fluorescent speckle microscopy, a method to visualize the dynamics of protein assemblies in living cells

1998 • 338 citations

Video Microscopy

1986 • 334 citations

Behavior of centrosomes during fertilization and cell division in mouse oocytes and in sea urchin eggs.

1986 • 330 citations

Direct interaction of microtubule- and actin-based transport motors

1999 • 329 citations

Targeting, Capture, and Stabilization of Microtubules at Early Focal Adhesions

1998 • 323 citations

Identification of Novel Graded Polarity Actin Filament Bundles in Locomoting Heart Fibroblasts: Implications for the Generation of Motile Force

1997 • 312 citations

Myosin is involved in postmitotic cell spreading.

1995 • 306 citations

Fibroblast contractility and actin organization are stimulated by microtubule inhibitors

1989 • 303 citations

Opposing motor activities are required for the organization of the mammalian mitotic spindle pole.

1996 • 301 citations

Taxol-induced microtubule asters in mitotic extracts of Xenopus eggs: requirement for phosphorylated factors and cytoplasmic dynein.

1991 • 300 citations

Effect of colcemid on the locomotory behaviour of fibroblasts

1970 • 296 citations

Cortical and cytoplasmic flow polarity in early embryonic cells of Caenorhabditis elegans.

1993 • 293 citations

Astral Microtubule Dynamics in Yeast: A Microtubule-based Searching Mechanism for Spindle Orientation and Nuclear Migration into the Bud

1997 • 284 citations

Positive feedback interactions between microtubule and actin dynamics during cell motility

1999 • 256 citations

The Road Less Traveled: Emerging Principles of Kinesin Motor Utilization

1999 • 254 citations

Microtubule release from the centrosome

1997 • 252 citations

An Essential Role for Katanin in Severing Microtubules in the Neuron

1999 • 247 citations

NuMA is required for the organization of microtubules into aster-like mitotic arrays.

1995 • 242 citations

Distribution of microtubule organizing centers in migrating sheets of endothelial cells.

1981 • 238 citations

Cytokinesis in eukaryotes: a mechanistic comparison

1999 • 238 citations

Contraction due to microtubule disruption is associated with increased phosphorylation of myosin regulatory light chain.

1995 • 229 citations

Coronin Promotes the Rapid Assembly and Cross-linking of Actin Filaments and May Link the Actin and Microtubule Cytoskeletons in Yeast

1999 • 222 citations

Corequirement of Specific Phosphoinositides and Small GTP-binding Protein Cdc42 in Inducing Actin Assembly in Xenopus Egg Extracts

1998 • 219 citations

The role of actin in the temperature-dependent gelation and contraction of extracts of Acanthamoeba.

1976 • 216 citations

Microtubule Disruption Induces the Formation of Actin Stress Fibers and Focal Adhesions in Cultured Cells: Possible Involvement of the Rho Signal Cascade.

1996 • 214 citations

Wound-induced assembly and closure of an actomyosin purse string in Xenopus oocytes

1999 • 210 citations

Mammalian cells express three distinct dynein heavy chains that are localized to different cytoplasmic organelles.

1996 • 203 citations

Cytokinesis in Animal Cells

1996 • 201 citations

Cell division without mitotic apparatus in sea urchin eggs

1956 • 196 citations

New horizons for cytokinesis

1995 • 196 citations

The dynactin complex is required for cleavage plane specification in early Caenorhabditis elegans embryos

1998 • 195 citations

Mitosis in vertebrate somatic cells with two spindles: Implications for the metaphase/anaphase transition checkpoint and cleavage

1997 • 170 citations

Feedback Interactions between Cell–Cell Adherens Junctions and Cytoskeletal Dynamics in Newt Lung Epithelial Cells

2000 • 167 citations

Xenopus nonmuscle myosin heavy chain isoforms have different subcellular localizations and enzymatic activities.

1996 • 167 citations

An Epidermal Plakin That Integrates Actin and Microtubule Networks at Cellular Junctions

2000 • 165 citations

Cell cycle regulation of dynein association with membranes modulates microtubule-based organelle transport.

1996 • 163 citations

Microtubule Treadmilling in Vivo

1997 • 159 citations

Mechanism of the formation of contractile ring in dividing cultured animal cells. I. Recruitment of preexisting actin filaments into the cleavage furrow.

1990 • 157 citations

Cell cycle control of microtubule-based membrane transport and tubule formation in vitro.

1991 • 142 citations

A Class VI Unconventional Myosin Is Associated with a Homologue of a Microtubule-binding Protein, Cytoplasmic Linker Protein–170, in Neurons and at the Posterior Pole of Drosophila Embryos

1998 • 130 citations

Dynein motor regulation stabilizes interphase microtubule arrays and determines centrosome position

1999 • 120 citations

Tyrosine phosphorylation is required for actin-based motility of vaccinia but not Listeria or Shigella

1999 • 112 citations

Membrane/microtubule tip attachment complexes (TACs) allow the assembly dynamics of plus ends to push and pull membranes into tubulovesicular networks in interphase Xenopus egg extracts.

1995 • 109 citations

Pseudopodial activity at the active edge of migrating fibroblast is decreased after drug‐induced microtubule depolymerization

1991 • 104 citations

[26] Isolation of mammalian centrosomes

1986 • 96 citations

Microtubules suppress actomyosin-based cortical flow in Xenopus oocytes

1997 • 95 citations

Dynein Intermediate Chain Mediated Dynein–Dynactin Interaction Is Required for Interphase Microtubule Organization and Centrosome Replication and Separation inDictyostelium

1999 • 91 citations

Chapter 23 Preparation and Purification of Dynein

1982 • 82 citations

Cleavage Furrows Formed between Centrosomes Lacking an Intervening Spindle and Chromosomes Contain Microtubule Bundles, INCENP, and CHO1 but Not CENP-E

1999 • 78 citations

Localization of myosin-V in the centrosome

1998 • 75 citations

Myosin Va associates with microtubule-rich domains in both interphase and dividing cells

1998 • 74 citations

The Cell in Development and Heredity

2015 • 65 citations

Direct observation of microtubule-f-actin interaction in cell free lysates

1999 • 60 citations

Analysis of Cortical Flow Models In Vivo

2000 • 57 citations

A High‐Resolution Multimode Digital Microscope System

2007 • 49 citations

Centrosome dynamics in early embryos of Caenorhabditis elegans

1998 • 47 citations

Cdc42 is required for membrane dependent actin polymerization in vitro

1998 • 44 citations

Chapter 10 A High-Resolution Multimode Digital Microscope System

1998 • 42 citations

Chapter 9 Fluorescent Speckle Microscopy of Spindle Microtubule Assembly and Motility in Living Cells

1998 • 36 citations

Cytochalasin effects on BALB/3T3 fibroblasts: Dose-dependent, reversible alteration of motility and cytoplasmic cleavage

1971 • 33 citations

The Interaction of Mip-90 with Microtubules and Actin Filaments in Human Fibroblasts

1998 • 28 citations

[43] Preparation and purification of dynein

1982 • 28 citations

Interaction of Chicken Gizzard Smooth Muscle Calponin with Brain Microtubules

1997 • 27 citations

Effects of cytochalasin and colcemid on cortical flow in coelomocytes

1993 • 24 citations

Centrosome dynamics in early embryos of Caenorhabditis elegans

1998 • 12 citations

Production and presentation of digital movies

1997 • 11 citations

Xenopus Egg Extracts as a Model System for Analysis of Microtubule, Actin Filament, and Intermediate Filament Interactions

2003 • 10 citations

Contribution of actomyosin to microtubule transport in motile and non-motile cells.

1999 • 1 citations